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SP_1854

Victor ID 3261
Gene Name SP_1854
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930980
NCBI Protein GI 15901682
Locus Tag SP_1854
Protein Accession NP_346286.1
Other Database IDs UniProtKB-ID: Q97NZ5_STRPN
UniRef100: UniRef100_E0SXB3
UniRef90: UniRef90_E0SXB3
UniRef50: UniRef50_A4VZG9
UniParc: UPI00000519FE
EMBL: AE005672
EMBL-CDS: AAK75926.1
RefSeq_NT: NC_003028.3
HSSP: P15039
EnsemblGenome: EBSTRG00000026696.
EnsemblGenome_TRS: EBSTRT00000026696
EnsemblGenome_PRO: EBSTRP00000025788
GenomeReviews: AE005672_GR
KEGG: spn:SP_1854
TIGR: SP_1854
HOGENOM: HBG753640
OMA: FRNYSQA
ProtClustDB: CLSK560226
BioCyc: SPNE170187-1:SP_1854-MONOMER
Taxonomy ID 170187
Gene Starting Position 1761890
Gene Ending Position 1762897
Gene Strand (Orientation) +
Protein Name galactose operon repressor
DNA Sequence 
>gi|194172857:1761890-1762897 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGGCTACCTTAAAAGACATTGCACAGCTAGCCTCTGTCTCTATCGCGACCGTATCCCGCGTCCTCAAC
CGCGACCAGAGCCTATCTGTTACAGAAGAAACCAGACACCGTATTTTAACCGTTGCTGAAGAGCTGGGCT
ACACCAAGCACCTCAAGACAGGCGAGTCCCACAAACCCAAGCAAAAGATTGCCATTATCCAATGGGTCAG
CGAACAAGGGGAGCTGGACGACCTCTACTACTACCAGATTCGCCTAGGAATAGAAAAAAGAGCCCAAGAG
TTGGACTATGATATCTTGCGCTATTTTAATGACCACCCTTTTACCCTAAGCGAGGAAGTGATTGGGATTC
TCTGCATCGGAAAGTTTAGTCGAGCTCAGATTTCTGCCTTTGAAGAATACCAAAAGCCTCTTGTATTTCT
AGACAGCGATACACTTTCCCTGGGACATACCTGTATTATCACGGATTTTTACACTGCTATGAAACAGGTT
GTCGATTATTTCCTCAGTCAAGGAATGGACCGTATCGGGATTCTAACAGGCCTTGAAGAAACAACAGACC
AAGAAGAAATCATTCAGGACAAGCGTCTAGAAAACTTCAAAAACTATAGTCAAGCGAGGGGAATCTATCA
TGATGAACTGGTCTTTCAAGGAAGATTTACTGCCCAGTCTGGCTATGACTTAATGAAGGAGGCCATTCAG
AGCTTGGGAGACCAACTTCCGCCAGCATTTTTCGCAGCCAGCGATAGTTTAGCTATCGGTGCCCTCCGTG
CCCTCCAAGAAGCTGGAATCAGCCTGCCAGATCGCGTCAGCCTCATTTCCTTTAACGACACTAGTCTGAC
CAAACAGGTCTATCCTCCCCTCTCTAGTATTACAGTTTATACTGAAGAAATGGGCCGAGCAGGTATGGAT
ATTCTTAACAAGGAAGTCCTCCACGGTCGGAAAATCCCTAGCCTGACCATGCTGGGAACCAGACTGACAT
TAAGAGAAAGTACCCTAAATCAAGAATA
Protein Sequence 
>gi|15901682|ref|NP_346286.1| galactose operon repressor [Streptococcus pneumoniae TIGR4] MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEELGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYFNDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAMKQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGRFTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFNDTSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1854 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1609K, under K: Transcription
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].