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SP_1855

Victor ID 3260
Gene Name SP_1855
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930979
NCBI Protein GI 15901683
Locus Tag SP_1855
Protein Accession NP_346287.1
Other Database IDs UniProtKB-ID: Q97NZ4_STRPN
UniRef100: UniRef100_E0TTB3
UniRef90: UniRef90_E0TTB3
UniRef50: UniRef50_C6A5X1
UniParc: UPI00000519FF
EMBL: AE005672
EMBL-CDS: AAK75927.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025616.
EnsemblGenome_TRS: EBSTRT00000025616
EnsemblGenome_PRO: EBSTRP00000024708
GenomeReviews: AE005672_GR
KEGG: spn:SP_1855
TIGR: SP_1855
HOGENOM: HBG753318
OMA: ASQIVLM
ProtClustDB: CLSK884166
BioCyc: SPNE170187-1:SP_1855-MONOMER
Taxonomy ID 170187
Gene Starting Position 1762943
Gene Ending Position 1763980
Gene Strand (Orientation) -
Protein Name alcohol dehydrogenase, zinc-containing
DNA Sequence 
>gi|194172857:1762943-1763980 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTATTCGATTACAATCATAGACTTAATTGTCTTACGTTCATCCATATCTTTATAGGCTTGGTCGATATC
TTCCAGTTTATAACTTGAAGTAAAGACGCGACCTGGATTGATATCACCATCAAGGACGGCTTTTAGTAAA
AATTGCTTATCGTATGTTGTAGCAGAAGCTGCCCCACCTGCTACAGAGATATTTTGCATAAATGTCGAAC
CAAGAGCACGATTATTATAGTGTGGGACTCCTACAAAGCCCATACGCCCTCCATTATGAAGAACACCTAG
CGCCTGTTCTATAGCAGCCTCCGTACCAACACATTCAAGTGCTGCATCTGCTCCTCCACCGAGGATTTCA
CGCACCTTGGTAATTCCTTCTTGACCACGTTCTGCAACAACAGCTGTCGCACCTGACTCCATAGCCATCT
TTTGACGGTCTTCATGACGGCTCATAAGGATAATTTGTGATGCTCCACGCATCTTAGCCGCGATGACAGC
ACATTGACCAACAGCCCCATCACCGATAACAACAACCTTGTCCCCTTTTTGAACATTTGCAACACGCGCC
GCATGATAGCCTGTCGGCATGACATCTGCAAGAGTCAAAAGGGACTTGAGCATCCCTTCTGTATAGTCAG
AAGGTTGACCAGGGATTTTAACCAGCGCCCAGTTTGCATAGTGGAAGCGAATATATTCTGCCTGAAAATC
ACCCCCCAAATTATTGCCAATATGATTGTCGCAAGAACCGTCAAATCCAGCAAGACAGGCATCACACTCA
CCACATCCATGTGTAAAAGGGACAATCACAAAATCACCTGGTTTCACCGTCGTAATGGCTTCCCCAGCTT
CTTCAACAATCCCAATCGCTTCGTGTCCACTATTTTTGTGTCCAGCTTTCGTTTCTGGATTACGGTACCT
CCATAAATCTGAACCACAAACGCACGCACGAACCACACGAATAATCACATCATCCGCTTCTATTATTTGC
GGACGTTCAATGCTAGCAAGTCCAACCTGACCTGCCTTTGTATATACTGCTGATTTCA
Protein Sequence 
>gi|15901683|ref|NP_346287.1| zinc-containing alcohol dehydrogenase [Streptococcus pneumoniae TIGR4] MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWRYRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGSCDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHAARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVVAERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRALGSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDERKTIKSMIVIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1855 mutation is attenuated in mice (Hava and Camilli, 2002).
COG COG1063ER, under E: Amino acid transport and metabolism; R: General function prediction only
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].