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SP_1861

Victor ID 3257
Gene Name SP_1861
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930972
NCBI Protein GI 15901689
Locus Tag SP_1861
Protein Accession NP_346293.1
Other Database IDs UniProtKB-ID: Q9XBN6_STRPN
UniRef100: UniRef100_E0SXC0
UniRef90: UniRef90_E0SXC0
UniRef50: UniRef50_A5I2A6
UniParc: UPI0000051A05
EMBL: AF162655
EMBL: AE005672
EMBL-CDS: AAD45529.1
EMBL-CDS: AAK75933.1
RefSeq_NT: NC_003028.3
HSSP: Q58206
EnsemblGenome: EBSTRG00000025371.
EnsemblGenome_TRS: EBSTRT00000025371
EnsemblGenome_PRO: EBSTRP00000024463
GenomeReviews: AE005672_GR
KEGG: spn:SP_1861
TIGR: SP_1861
HOGENOM: HBG758042
OMA: NELDLEC
ProtClustDB: CLSK877158
BioCyc: SPNE170187-1:SP_1861-MONOMER
Taxonomy ID 170187
Gene Starting Position 1768968
Gene Ending Position 1769696
Gene Strand (Orientation) -
Protein Name choline transporter
DNA Sequence 
>gi|194172857:1768968-1769696 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATTAGTCATGAACACTACCTCCAAACAAGTCTGCTACAAAGTCTGTTGCAGGCGCTTTTAAAATTGTCTC
GGGATTCGCTACCTGGCGAATTTCTCCATCCTGCAAGACAGCAATACGGTCCGCCAACTTCAAGGCTTCA
TCCGTATCATGGGTTACAAAAATCGTTGTCATCCCAAACTCTTTATGCAATTCTTTTGTCAGAACCTGCA
ACTGTTTTCTCGAAATAGCATCCAAGGCCGAAAAGGGTTCATCCATGAGGAAAATCTTGGGCTGACCAAT
CATAGCTCGGACAATACCGACCCGTTGCTGTTCTCCACCAGATAATTCACTAGGTAAGCGATGCCCATAC
TCGGCTACTGGTAAACCAACCTTAGCCAAAAGCTCTTCTGTTTTCTTCGTAATTTCTTCCTTGCTCCACC
CCTTCATTTCAGGAATGAGAGCAATATTTTCCGCAACTGTTAGATTTGGAAAAAGAGCAATAGCCTGTAA
AACATAACCAGTAGAAAGACGAAGTTCACGCTCATCATAGTCTTTGATGCGCTTCCCATCCATATAAATA
TTTCCATCAGTTGGTTCCAAAAGACGGTTAATCATCTTGAGCATGGTCGTCTTACCTGACCCAGAAGGCC
CTACTAAAACCATAAATTCCCCATCCTCAATCTGTAAGTTGACATCTCTCAAGACATCCTTTTCTGTGTA
GCGCAGTGCTACATTTTTGTATTCAATCA
Protein Sequence 
>gi|15901689|ref|NP_346293.1| choline transporter [Streptococcus pneumoniae TIGR4] MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTMLKMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEMKGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMDEPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVANPETILKAPATDFVADLFGGSVHD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1861 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1125E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].