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SP_1898

Victor ID 3251
Gene Name SP_1898
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930935
NCBI Protein GI 15901725
Locus Tag SP_1898
Protein Accession NP_346329.1
Other Database IDs UniProtKB-ID: Q97NW1_STRPN
UniRef100: UniRef100_A5MRG5
UniRef90: UniRef90_E0SXF9
UniRef50: UniRef50_E0SXF9
UniParc: UPI0000051A2B
EMBL: AE005672
EMBL-CDS: AAK75969.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026320.
EnsemblGenome_TRS: EBSTRT00000026320
EnsemblGenome_PRO: EBSTRP00000025412
GenomeReviews: AE005672_GR
KEGG: spn:SP_1898
TIGR: SP_1898
HOGENOM: HBG302872
OMA: RNDLGMM
ProtClustDB: CLSK626013
BioCyc: SPNE170187-1:SP_1898-MONOMER
Taxonomy ID 170187
Gene Starting Position 1804474
Gene Ending Position 1806636
Gene Strand (Orientation) -
Protein Name alpha-galactosidase
DNA Sequence 
>gi|194172857:1804474-1806636 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATCATAGTTTTCTAAAAATATACTGTCTACTCAAAAAATCTCCTTGGGATAAGATAACAGTTAAGCCCGC
ATACATTAGTTCTGCACCTGAGTAAACTTCGCCATTTTCCTGTAATTTATATAGTCCCTCTTCATCCAAA
TCTTTTAATTTTAAAGTTGTTTCCATGGTCTCTACAACAGATAAAACGCGAACGTAGGTTACAATCGTTT
GATTTCCGTAATTAAATTGTACAGCTGCTTCATTGGATACAGTATCAGGATTAATTAGTCTATACTGCTG
TCCTAACTGAACTACTGGTCGTAATTCTTTATACAAGTTCACCTGATTAGCAATCGTAGCTTTCTCTTCA
TCTGATAAATTTGTCAAATCAAGTTCATAGCCCAAATTTCCCATCATTGCTACAAGGCCACGTGTTTCTA
ATGGTGTCATTCGTCCCATCTGATGATTCGGTACTGCTGACACATGAGCCCCCATAGAAATGGTTGGATA
GAGATAGGATGAACCGTATTGAATTGGTAAACGTGCAATGGCATCAGTATTATCACTAGCCCAGACTTGT
GGGAAATAGCGCATCATACCAAGATCATTTCGTCCACCACCACCAGAGCAGGACTCAAAGAGAATATGGC
TGTGCTTCTCTGTCAGATAAGAAACGAGTTCATAAAGCCCCAGCATGTACTGATGAGATTGCATCTGTGT
CTCTAGATAAGTTAATCCATTCCCTAGCTTAGTGATATTGCGGTTCATATCCCATTTAATGTAATCAATA
TCATGATAAAATAGGAGTTGATCTAAGACACTTTTCAAGTATTCTACTACCTGAGGATTGGCAAGATTAA
GTACTAATTGATTCCGAGAATAAGTATGCTCATAGCCAGGAACCTGAATAGCCCAGTCAGGATGTTGACG
ATACAAATCACTATCTACAGAAATCATTTCGGGTTCTAACCAAAGTCCAAACTGCAAACCTCTTTCATGG
ATAGCTGAAATCAGACTTTCTAGACTTCCACCCAGTTTTTCCTCATTAACAACCCAATCACCTAAAGCAC
GATTATCATCAAAACGATTGCCAAACCAACCATCATCTAATACAAAAAGTTCAATGCCAACTTTCTTAGC
TTCATCTGCTAACTCTAACAGTTTTTCTCTCTGAAAGTCAAAGTAAGTAGCTTCCCAGTTATTGATTAGA
ATTGGACGTTCTTTTTTAGAAAATTCACTTAGCATAATGTGCTTCAGTACAAAATTCTGACTTTCATGAC
TAATACCAGTTAATCCCTGATCTGAATGAGTCACTAAAGCTACCGGTGTTTCAAAGTATTCCTCAGGAGC
TAACTTCCAAGAAAAGTTTTCTGGATTAATGCCAATAGCCACCCGAACTTCATTCAATTGATTTTTTTGA
ACAAAAGCTTCAAAGTTGCCACTATACATTAGTTGAATAGCAAACACATTCCCAGCATCCTCTGTGACTC
CTTGTTCGCATAGTAGAAGAGCTGGTGTTTGAGCATGACCAGAAGCACCTCGGTTTGAACTAATCGAAAA
GATTCCTTGTTCTACCTGTTGACGTCTAACAGTCTTTTCACGAGCATAAGCACCCTGCAGAGTTACTATT
TCGTAATCTGCAGCTGGAAAATCAGCCATAAAAGAAAAATCTTTATGGATGACAACTTCCTGATTACTAT
TATTATCTAATTTACTGTAGCTAGCAATAGTCGCATCATTATTAAAAGTAGTATAATACAAAGTCAGACT
AAGTTGAGCCTTAGAATCTTCTAACATTAAGACAAGAGTCTCTGTATCGTCCATGCTATGTGGAGAAGGT
AAGCCCTGTGGACCATTCTGACCTTTTAAAATCTTTGCTTCTACAAATCGAAAGTCTGTTACTTCAGTTA
CACTATGCTGAACCTGTATGGTTGGTTTCCTAAAATCTCCTAAGCCATGTTGTCCAAAAATCTGTCGCTG
AGTATCTAAACTAAAGGTTCGATTAGTAGCCGTTGGATTTCCTGAAAAGGCATGGTCTCGTTCATAAACA
CTATTGGAACCTTTATAGTTCTTAATAGTCTTTCCTAAATGTTTCAAAAGTAAGTAGCCATTTCGATTTT
CAATAATCAAACTTAGATTTTTACTCTCAACATAAAATAGATTATTCTCTATCCTAACTCCCA
Protein Sequence 
>gi|15901725|ref|NP_346329.1| alpha-galactosidase [Streptococcus pneumoniae TIGR4] MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSNSVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVEAKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLDNNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGASGHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSWKLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATYFDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLISAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVVEYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLTEKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGAHVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPVVQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLYKLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1898 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG3345G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].