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SP_0943

Victor ID 3249
Gene Name SP_0943
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930896
NCBI Protein GI 15900822
Locus Tag SP_0943
Protein Accession NP_345426.1
Other Database IDs UniProtKB-ID: TRMFO_STRPN
UniRef100: UniRef100_B2IP98
UniRef90: UniRef90_Q04KY2
UniRef50: UniRef50_Q02YZ3
UniParc: UPI000012B4AA
EMBL: AE005672
EMBL-CDS: AAK75066.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025645
EnsemblGenome_TRS: EBSTRT00000025645
EnsemblGenome_PRO: EBSTRP00000024737
GenomeReviews: AE005672_GR
KEGG: spn:SP_0943
TIGR: SP_0943
HOGENOM: HBG285041
OMA: FEGCLPI
ProtClustDB: PRK05335
BioCyc: SPNE170187-1:SP_0943-MONOMER
Taxonomy ID 170187
Gene Starting Position 892923
Gene Ending Position 894293
Gene Strand (Orientation) +
Protein Name tRNA (uracil-5-)-methyltransferase Gid
DNA Sequence 
>gi|194172857:892923-894293 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGGACTTAGGTCCCACCCAAAGAGGTATTAGTGTCGTGTCTCAATCTTATATCAATGTTATCGGTGCT
GGTTTGGCAGGTTCTGAAGCAGCTTACCAAATCGCAGAGCGTGGTATTCCAGTTAAACTATATGAAATGC
GTGGTGTCAAGTCTACACCCCAGCATAAAACAGACAATTTTGCTGAGTTGGTTTGTTCCAATTCTTTGCG
TGGGGATGCTTTGACAAATGCAGTTGGTCTTCTCAAGGAAGAAATGCGTCGCTTGGGTTCTGTTATCTTG
GAATCTGCTGAGGCTACACGTGTTCCTGCAGGTGGTGCCCTTGCAGTGGACCGTGATGGTTTCTCTCAAA
TGGTGACCGAAAAAGTTGCCAACCACCCCTTGATTGAAGTGGTTCGTGATGAAATTACAGAATTGCCGAC
AGATGTTATTACGGTTATCGCTACTGGTCCTTTGACAAGTGATGCCTTGGCTGAAAAGATTCATGCTCTT
AATGACGGTGCTGGTTTTTATTTCTACGATGCGGCAGCGCCTATTATCGATGTCAACACTATCGATATGA
GCAAGGTCTACCTCAAATCACGTTATGATAAGGGAGAAGCGGCCTACCTCAATGCCCCTATGACCAAGCA
AGAATTTATGGATTTCCATGAAGCTTTGGTCAATGCAGAAGAAGCACCGCTTAGTTCTTTTGAAAAAGAA
AAGTACTTTGAAGGATGTATGCCTATCGAAGTCATGGCCAAACGTGGCATTAAAACTATGCTTTATGGCC
CTATGAAGCCAGTCGGTCTTGAGTACCCAGACGACTATACAGGACCTCGTGATGGAGAATTTAAAACACC
TTATGCGGTTGTGCAACTTCGTCAGGATAATGCAGCTGGTAGCCTCTACAATATTGTTGGTTTCCAGACC
CACCTCAAATGGGGAGAACAAAAGCGTGTCTTCCAAATGATTCCGGGTCTTGAAAATGCGGAGTTTGTCC
GTTATGGTGTGATGCATCGCAATTCTTACATGGATTCACCAAATCTTCTTGAGCAGACTTACCGTTCTAA
GAAACAACCAAATCTCTTCTTTGCTGGTCAAATGACGGGTGTGGAAGGCTATGTTGAGTCGGCGGCTTCA
GGCTTAGTTGCGGGAATTAACGCAGCTCGTCTCTTCAAGGAAGAAAGCGAGGCTATTTTCCCCGAGACGA
CAGCGATTGGAAGCTTAGCTCATTACATTACCCATGCCGACAGCAAACATTTCCAACCAATGAATGTCAA
TTTTGGGATCATCAAGGAGTTGGAAGGCGAGCGTATCCGTGATAAGAAGGCTCGTTATGAAAAAATTGCA
GAGCGTGCCCTTGCCGACTTAGAGGAATTTTTGACTGTCTA
Protein Sequence 
>gi|15900822|ref|NP_345426.1| tRNA (uracil-5-)-methyltransferase Gid [Streptococcus pneumoniae TIGR4] MDLGPTQRGISVVSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHKTDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGFSQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFYDAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLSSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTYRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAHYITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gid mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1206J, under J: Translation, ribosomal structure and biogenesis
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].