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SP_0916

Victor ID 3246
Gene Name SP_0916
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930869
NCBI Protein GI 15900796
Locus Tag SP_0916
Protein Accession NP_345400.1
Other Database IDs UniProtKB-ID: Q97RA9_STRPN
UniRef100: UniRef100_A5LC78
UniRef90: UniRef90_E0SYR9
UniRef50: UniRef50_D3QZK4
UniParc: UPI0000051635
EMBL: AE005672
EMBL-CDS: AAK75040.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026411.
EnsemblGenome_TRS: EBSTRT00000026411
EnsemblGenome_PRO: EBSTRP00000025503
GenomeReviews: AE005672_GR
KEGG: spn:SP_0916
TIGR: SP_0916
HOGENOM: HBG634412
OMA: WNTLVTE
ProtClustDB: CLSK884022
BioCyc: SPNE170187-1:SP_0916-MONOMER
Taxonomy ID 170187
Gene Starting Position 869868
Gene Ending Position 871343
Gene Strand (Orientation) +
Protein Name lysine decarboxylase
DNA Sequence 
>gi|194172857:869868-871343 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTGAAAGAGTTAGATCAAAACCAAGCCCCAATTTATGAGGCCTTGGTGAAGTTACGCAAGAAAAGGATT
GTTCCCTTTGATGTTCCAGGTCACAAGCGTGGACGGGGAAATCCAGAACTTGTCGAACTCTTAGGAGAAA
AATGTGTAGGCATTGATGTCAATTCGATGAAACCTTTGGATAATTTAGGCCATCCTATTTCGATTATTCG
TGATGCAGAGGAGCTGGCTGCAGATGCTTTTGGAGCTAGCCATGCCTTTCTAATGATTGGTGGAACAACT
TCATCGGTGCAGACTATGATTCTGGCAACCTGCAAGGCAGGAGATAAGATTATTCTGCCACGAAATGTCC
ATAAATCTGCTATCAATGCGTTGGTTCTATGTGGTGCCATTCCCATCTATATCGAGATGAGTGTAGATCC
TAAGATTGGTATCGCTTTAGGTCTTGAAAATGACCGAGTAGCACAGGCCATAAAGGACCATCCAGATGCT
AAGGCTATCCTAATCAACAATCCTACTTACTACGGCATCTGTTCAGACCTAAAGGGGTTGACAGAAATGG
CTCATGAAGCTGGCATGATGGTTTTAGTAGATGAAGCCCACGGAGCGCATTTGCATTTCACTGATAAACT
TCCAATTTCTGCTATGGATGCAGGGGCTGATATGGCAGCAGTTTCCATGCATAAGTCTGGTGGGAGTTTG
ACCCAAAGCTCCATTTTACTTATCGGGGAGCAGATGAATTCTGAATACGTTCGTCAGATAATTAACCTGA
CCCAGTCTACATCTGCCTCTTACTTGTTGATGGCTAGTTTGGATATTTCACGTCGCAACTTGGCCCTTCG
TGGTAAAGAGTCGTTTGAGAAAGTCATTGAGCTATCTGAGTATGCCCGCCGTGAAATCAATGCTATCGGT
GGCTACTATGCCTACTCAAAAGAGTTAATAGACGGTGTTTCGGTTTGCGATTTTGACGTAACTAAGCTGT
CAGTTTACACTCAGGGTATTGGCTTAACAGGTATCGAGGTTTATGACCTCTTGCGAGACGAATACGACAT
TCAGATCGAGTTTGGTGATATCGGCAATATCTTGGCCTATATTTCCATCGGCGACCGCATCCAAGACATC
GAGCGCTTGGTTGGTGCTCTGGCTGATATTAAGAGACTCTATTCAAGAGATGGAAAAGATTTGATAGCAG
GAGAATATATTCAGCCCGAGTTAGTGCTGTCTCCGCAAGAAGCCTTCTATTCAGAAAGAAAAAGTTTAAC
TTTGGATGATTCTGTTGGACAGGTCTGTGGAGAATTTGTTATGTGTTACCCTCCAGGTATTCCTATCTTG
GCTCCTGGTGAACGCATTACACGAGAAATTGTCGACTATATCCAATTCGCCAAGGAACGTGGTTGCTCCC
TCCAAGGGACGGAAGATCCAGAGGTCAATCATATCAACGTTATTAAGAGAAAGACAAACTATAAGAAAAG
TCAATA
Protein Sequence 
>gi|15900796|ref|NP_345400.1| lysine decarboxylase [Streptococcus pneumoniae TIGR4] MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELLGEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILATCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDHPDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAGADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRNLALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIGLTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGKDLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERITREIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0916 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1982E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].