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SP_0892

Victor ID 3245
Gene Name SP_0892
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930845
NCBI Protein GI 15900775
Locus Tag SP_0892
Protein Accession NP_345379.1
Other Database IDs UniProtKB-ID: Q97RD0_STRPN
UniRef100: UniRef100_Q97RD0
UniRef90: UniRef90_B1IB61
UniRef50: UniRef50_Q04L29
UniParc: UPI00000C9CAD
EMBL: AE005672
EMBL-CDS: AAK75019.1
RefSeq_NT: NC_003028.3
HSSP: Q56243
REBASE: 5196
EnsemblGenome: EBSTRG00000025222.
EnsemblGenome_TRS: EBSTRT00000025222
EnsemblGenome_PRO: EBSTRP00000024314
GenomeReviews: AE005672_GR
KEGG: spn:SP_0892
TIGR: SP_0892
HOGENOM: HBG286970
OMA: IFYTNGY
ProtClustDB: CLSK559947
BioCyc: SPNE170187-1:SP_0892-MONOMER
Taxonomy ID 170187
Gene Starting Position 840199
Gene Ending Position 843474
Gene Strand (Orientation) +
Protein Name type I restriction-modification system, R subunit, putative
DNA Sequence 
>gi|194172857:840199-843474 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGATTGCTACATCAACTGTGGCTACTGCCTTTATGGCGCGTCGTGCTTTAGAGCAGGCTGTCCATTGG
ATATATAGTCACGATTCATATTTAGAAGCTCCCTATCGTGCTACTCTATCTTCTTTAGTATGGGATGATG
ATTTTAGGGATATCGTAGATTCTGAACTCCACAAGCAGATAGTTCTGTTGATTCGGTGGGGAAACCATGC
TGCTCATGGTGGTGAAATTAAGGAACGAGAAGCGATTTTAGCTTTGCATCATTTGTATCAGTTTGTTAAT
TTTATCGATTATTGTTACAGCAATGAGTTTGTGGAGCGTTATTTTGATGAGAAGTGCTTACCACTTTCAG
CAAACATCAAATACCGAGAAACTCCACAATCTATGATAAAGTTACAAGACAGTTTACCAGAACTGCCTGA
TTTTCATGAACAGATGGCTGCTCAGTCCGTAGAAGTTCAAGAGACTTATACTGAAAAACGTGAGACTGCA
GCGCAACGGCAAGATGTGCCTTTCCATATTGATCAATTATCTGAGGCAGAGACAAGAAAGCTCTTTATTG
ATATCGATCTCCGTTTAGCAGGATGGATATTTGAAGAAAACTGTCGTGTTGAGATAGCCGTTGATGGTCT
CAAGCACGGTTCAGGAATTGGTTACTGTGACTATGTACTTTATGGTAAAAATGGGAAAATTTTAGCGATT
GTGGAGGCTAAAAAAGCCTCTGTCAATCCAGAAGTAGGGGAAGTACAGGTCAAAGAATATGCTGAAGCTT
TGGAGAAACATATCGGCTATCAGCCAATTTGCTTTATTACAAATGGGTTGAAGCACTATATACTTGATGG
TCCGAACCGCCGCCAGATTGCAGGCTTTTACTCTCAAGAAGAATTGCAATTAGTGATGGATAGACGTCAT
CTTCAAAAACCGCTTGAGGATATTTCTAGTAAAATTAGGGACGATATTTCCGGGCGTCACTACCAAAAAC
ATGCCATTGCAAGCGTTTGTGAAGCTTTCTCTGATCATCGTAGACAGGCACTTTTGGTTATGGCAACTGG
GGCGGGGAAAACTCGTACAGCAGTTTCTCTAGTTGATATCTTATCACGTCATAACTGGGTAAAAAACGTT
CTCTTCTTAGCCGATAGAACTTCCTTGGTTAAGCAAGCATATGATTCGTTTAGAAAATTACTCCCAGATC
TTTCCGTTTGTAACTTCTTAGAAGATAAAGAAGGAGCTCAATCAAGTCGCATGGTCTTTTCAACTTATCC
GACCATGATTGGAGCGATTAGTGGTCAAGAAGAAGTAAATCAACGCCCTTTCACTGTTGGGCATTTTGAC
CTTATCATAATTGACGAATCTCACCGTTCTATTTATCAGAAATACAAGTCCATTTTTGATTATTTTGATG
CAAGAATTGTAGGCTTAACAGCTACTCCGCGTCAAGATTTAGATAAAAACACCTATGGATTCTTTAATTT
GGAGAATGGGGTTCCAACATATGCATATGATTTGGAAGAGGCTGTTAAAGACGGATATTTAGTAGCCTAT
CATTCTATCGAAACCAAACTGAAACTACCTACGGATGGTCTACATTATGATGATTTGTCCGAAGAAGAAA
AGGAACATTTTGATAGCAAATTTGAAGACAATAGCTGTGAAAAAGATATTGATGGGAGTGTATTTAATTC
CTTTATTTTCAATAAAAGTACAGTAGAAATTGTTTTAAATGAACTCATGACAAGAGGAATTCAGACAGCC
TCGGGTGATGAAATTGGTAAAACTATTATTTTTGCTAAAAATCATGATCATGCGGAATATATCAGAGGTA
TTTTTAACAACCGCTATCCTGAAAAAGGGAGCGACTATGCTCAGGTGATTGATTATAGTATTAAGCATTA
TCAGACCTTGATTGATGATTTTAAAATTAAGGAGAAGTATCCTCAAATTGCGATTTCTGTCGATATGTTA
GATACAGGTATTGATGTACCAGAGGTTGTTAATTTAGTCTTCTTCAAGAAAGTACGCTCTAAAACTAAGT
TTTGGCAGATGATTGGTCGAGGAACCCGTCTATGTAAAGATTTATTTGGACCTGAGCAGGATAAGGAAAA
CTTCTTGGTATTTGATTATGGGGACAATTTTGATTATTTTCGTGCAGATCCAAGAGATGGAGAGGGTCGT
CACATTGTTTCGCTGACTCAGCGTTTATTTAATATCAAAGTGGACTTGATTCGAGAACTTCAGGGACTCC
AATACCAAGAAGATCAGTTTGCGAGAGCATACCGTCAGCAGCTTGTCTCGGAACTTCAAGGTCGTATAGA
GAGCTTAAATGAGTTGGACTTCAGGGTTCGTATGGTTTTAGATACAGTTTATAGCTATAGGAAATTGGAA
AGTTGGCAGAATCTAACTGCTGTTACAAGTGAAACCATTCAAAAAAATCTCTCTCCGCTTTTATTTGATG
AAGATAAAGAAGATGAGATGGCGAGGAGATTTGATTTGTGGTTGCTTCATATTCAGTTGGGGCAACTGAC
AGCTAAATCTTCCACTGTTCATATTTCCCAAGTGATGAAGACGGCTAGAGCTCTTTCTGCTATTGGCAAT
ATCCCGCAGGTTTTTGAGCAGGCTGAAATTATCAGGAAAGTACAGGAGCCTGAATTTTGGAAAGAAGTTA
ACTTGTCTGATTTGGAAAAAATTCGTCTTGCTATTCGAGATTTATTACAGTTTTTGGATAAAACAGACCG
TAAACCCTACTATGTTAACTTTGAAGATCGTATACTCTCCACTGTTCACGAGACCACAGCATTTTTGCAG
GTCAACGATCTTCGGTCTTACAATGAAAAAGTTGAGCATTATTTGAAAACTCATCTGGATGAGGAGTCCA
TTTCTAAGCTATACCATAATAAAAAGTTGACATCTGATGATATGCTTGCACTTGAAAAATTGCTTTGGGA
AAAATTAGGTAGTAAAGCAGACTACCAAAGTCATTATGAAAATAAGGCAATTCCGAGATTGGTTCGTGAG
ATTATTGGCTTAGATAGAGAGTCTGCCAATCGTATTTTTTCTAAATTTTTGTCGGATGAGAATCTTAATG
CCAGGCAGATTTCATTTGTAAAATTGATTGTAGACTACATTGTAGAAAATGGTTTTTTAGAGACGAAAGT
GTTAACGCAAGAGCCGTTTAAATCTTATGGTTCTGTTCAACTACTCTTCCAACACCAACTACCAGTACTT
CGTAATATTGTTCAAATCATTGAACTTATCAATAATCGAGCTGGAGAAGCGGCTTA
Protein Sequence 
>gi|15900775|ref|NP_345379.1| type I restriction-modification system, R subunit [Streptococcus pneumoniae TIGR4] MIATSTVATAFMARRALEQAVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIKEREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSLPELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLAGWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVKEYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLEDISSKIRDDISGRHYQKHAIASVCEAFSDHRRQALLVMATGAGKTRTAVSLVDILSRHNWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGAISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKNTYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFDSKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHDHAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGIDVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRADPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLNELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWLLHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLSDLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNIVQIIELINNRAGEAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0892 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG4096V, under V: Defense mechanisms
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].