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SP_0856

Victor ID 3241
Gene Name SP_0856
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930806
NCBI Protein GI 15900741
Locus Tag SP_0856
Protein Accession NP_345345.1
Other Database IDs UniProtKB-ID: Q97RG4_STRPN
UniRef100: UniRef100_E0TPU4
UniRef90: UniRef90_E0SY24
UniRef50: UniRef50_Q9ZJF1
UniParc: UPI00000515EE
EMBL: AE005672
EMBL-CDS: AAK74985.1
RefSeq_NT: NC_003028.3
HSSP: P00510
EnsemblGenome: EBSTRG00000026294.
EnsemblGenome_TRS: EBSTRT00000026294
EnsemblGenome_PRO: EBSTRP00000025386
GenomeReviews: AE005672_GR
KEGG: spn:SP_0856
TIGR: SP_0856
HOGENOM: HBG617123
OMA: YIKTDYR
ProtClustDB: PRK13357
BioCyc: SPNE170187-1:SP_0856-MONOMER
Taxonomy ID 170187
Gene Starting Position 803302
Gene Ending Position 804324
Gene Strand (Orientation) +
Protein Name branched-chain amino acid aminotransferase
DNA Sequence 
>gi|194172857:803302-804324 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGACAGTAACGATTGATTGGGAAAACCTCGGTTTTTCCTATATGAAATTACCTTATCGCTATCTTGCT
CATTTCAAAAATGGACAATGGGATCAAGGAGAGCTTACAGAGGATGCAACTTTGCATATTTCAGAGTCTT
CTCCAAGTCTTCACTATGGACAACAAGCATTTGAAGGTTTGAAAGCTTATCGTACTAAGGATGGCAGTGT
TCAACTGTTCCGTCCTGATGAAAATGCTAAACGTCTGCAACGTACATGTGACCGTCTCTTGATGCCACAA
GTTCCGACAGACATGTTTGTAGAAGCTTGTAAAGCAGTTGTCCGTGCGAATGAAGAATACGTACCACCAT
ACGGAACAGGTGGAACCTTATATCTTCGCCCTCTTTTGATTGGTGTCGGAGATATTATCGGGGTAAAACC
GGCAGAAGAGTACATTTTCACCATCTTTGCTATGCCAGTTGGAAATTACTTTAAAGGTGGTTTGGTCCCA
ACCAACTTCTTGATTCAGGATGAGTACGACCGTGCAGCACCAAATGGTACAGGTGCGGCTAAGGTTGGTG
GAAACTATGCTGCAAGTCTCTTACCAGGAAAAATGGCCAAGTCACGTCATTTCTCAGATGTTATCTATCT
GGACCCATCAACTCATACAAAGATTGAAGAAGTCGGATCAGCTAACTTCTTTGGAATTACAGCTGATAAT
GAATTTGTAACACCATTGAGTCCATCTATCTTGCCATCTATTACCAAGTATTCCTTGCTTTATTTGGCAG
AACATCGCTTGGGATTAACTCCTATTGAGGGTGATGTTCCAATTGATAATCTTGACCGTTTTGTAGAGGC
AGGTGCCTGTGGTACAGCAGCGGTTATTTCTCCAATTGGAGGTATTCAACATGGTGATGATTTCCATGTA
TTCTATAGTGAAACAGAAGTAGGTCCTGTGACGCGTAAATTATATAATGAATTGACGGGTATTCAGTTTG
GCGATATTGAAGCGCCAGAAGGTTGGATTGTAAAAGTAGATTA
Protein Sequence 
>gi|15900741|ref|NP_345345.1| branched-chain amino acid aminotransferase [Streptococcus pneumoniae TIGR4] MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHISESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEACKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGGLVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKIEEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDRFVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEGWIVKVD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0856 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0115EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].