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SP_0842

Victor ID 3240
Gene Name SP_0842
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930792
NCBI Protein GI 15900729
Locus Tag SP_0842
Protein Accession NP_345333.1
Other Database IDs UniProtKB-ID: Q97RH3_STRPN
UniRef100: UniRef100_Q97RH3
UniRef90: UniRef90_B8ZNP3
UniRef50: UniRef50_Q4L818
UniParc: UPI00000515DE
EMBL: AE005672
EMBL-CDS: AAK74973.1
RefSeq_NT: NC_003028.3
HSSP: P77836
EnsemblGenome: EBSTRG00000026060.
EnsemblGenome_TRS: EBSTRT00000026060
EnsemblGenome_PRO: EBSTRP00000025152
GenomeReviews: AE005672_GR
KEGG: spn:SP_0842
TIGR: SP_0842
HOGENOM: HBG288505
OMA: GCAIIGQ
ProtClustDB: PRK06078
Taxonomy ID 170187
Gene Starting Position 788996
Gene Ending Position 790273
Gene Strand (Orientation) +
Protein Name pyrimidine-nucleoside phosphorylase
DNA Sequence 
>gi|194172857:788996-790273 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGAGAGCAGTTGATTTAATCCAAAAAAAACGAGACGGTCAAGAACTGACTTCAAGTGAAATTGAATGG
CTGATAGAAGGCTATGTATCAGGAACTGTTCCTGATTATCAGATGTCTGCCTTTGCTATGGCTGTTTATT
TTAAAGGAATGACGACTCGAGAAATCTCTGATTTAACGATGAATATGGTTAAGACTGGGCAAGAGTTTGA
CCTGTCAGCCATTGATGGTGTGAAAGTTGACAAGCATTCTACTGGTGGTGTCGGCGATAAGGTAACCTTG
ATTTTAGCTCCTCTTGTTGCTAGCTTCGGTGTGCCTGTAGCAAAAATGAGTGGTCGTGGTCTTGGCCATA
CAGGCGGAACAATTGATAAATTGGAGTCCATTAAGGGCTATCAAGTAGAACGTAGTCAAGAGGATTTTAT
TCGTCAGGTTCAGGATATTGGAGTATCTGTCATTGGGCAATCAGACCAGCTGGTCAAAGCAGATAAGCTT
CTCTATGCCCTTCGTGATGTGACCGCAACTGTCGACACGATTCCTTTGATTGCGAGTTCGGTGATGAGCA
AGAAAATTGCGGCAGGGGCGGATGCTATTTTGCTAGACGTGACTGTCGGTGAGGGTGCCTTCATGAAGAC
GGTTGATGAGGCGCGTGAGTTGGCTCAAACTATGGTAGATCTTGGTAAGGTTGTTGGACGGAAGACAGTA
GCAGTGATTACGGATATGAGCCAGCCTTTGGGACGAGCGATTGGAAATCGTCTGGAAATCCTTGAAGCAT
TGGAGATTTTGCAAGGTCAAGGACGTCAGGATATTACCCACTTTATTTGTGAATTGGCTCAAATTATGCT
TGGTTTGGCAAATGTTAACAAAACTGTTGAAGAAGTTCACCAACATCTTGAGAATGGTCAAGCACTGGCT
AAGTTTGAGGAAATGGTGCAAGCCCAAGGTGGAGACTTGGAAGACCTCTATCGTCCTGTAAATGTAGCTC
ATGTGGTGGAAATCCCTGCTCAGGAAACGGGTGTCATTTCAGCTCTTCCAGCTATGGACTTTGGTCTTTA
TGCCATGAGGCTGGGTGCTGGTCGTGCAGTTAAGTCTGATGCCTTGGACTATGAAACAGGAATTGTTTTT
GAAAAGAAGATTGGAGACTCCGTTCAAAAGGGTGAAATTGTTGCAAAAGTATACACAAATGAAAAAATTC
CACCTCAACTAGTTACAGATTTCCAAAAATGTGTTAAAATAAGTGATGAAGTGAAAAAAATCCGTGAAAT
TGTAGAAATCATCTCCTA
Protein Sequence 
>gi|15900729|ref|NP_345333.1| pyrimidine-nucleoside phosphorylase [Streptococcus pneumoniae TIGR4] MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMAVYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASFGVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKADKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELAQTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELAQIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYTNEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0842 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0213F, under F: Nucleotide transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].