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sigL from Mycobacterium tuberculosis H37Rv

Victor ID 324
Gene Name sigL from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888609
NCBI Protein GI 15607875
Locus Tag Rv0735
Protein Accession NP_215249.1
Other Database IDs UniProtKB-ID: Q7D9D4_MYCTU
UniRef100: UniRef100_A1KGL6
UniRef90: UniRef90_A1KGL6
UniRef50: UniRef50_A0QSI0
UniParc: UPI00000D10AF
EMBL: AE000516
EMBL: BX842574
EMBL-CDS: AAK44993.1
EMBL-CDS: CAA17502.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 3HUG
EnsemblGenome: EBMYCG00000002872.
EnsemblGenome_TRS: EBMYCT00000002874
EnsemblGenome_PRO: EBMYCP00000002874
EnsemblGenome: EBMYCG00000071090.
EnsemblGenome_TRS: EBMYCT00000071095
EnsemblGenome_PRO: EBMYCP00000069154
GenomeReviews: AE000516_GR
Taxonomy ID 83332
Gene Starting Position 827542
Gene Ending Position 828075
Gene Strand (Orientation) +
Protein Name RNA polymerase sigma factor SigL
DNA Sequence 
>gi|57116681:827542-828075 Mycobacterium tuberculosis H37Rv, complete genome
CGTGGCTCGTGTGTCGGGCGCCGCGGCCGCTGAAGCCGCGTTGATGAGGGCGCTCTACGACGAGCATGCC
GCCGTGTTGTGGCGTTACGCGCTGCGCTTGACCGGGGATGCGGCCCAAGCCGAAGACGTCGTCCAAGAGA
CGCTGTTGCGGGCGTGGCAGCATCCGGAGGTGATCGGCGACACCGCGCGGCCGGCAAGGGCGTGGTTGTT
CACCGTCGCGCGCAACATGATCATCGACGAGCGGCGCAGCGCCCGGTTCCGCAATGTGGTCGGTTCGACC
GACCAATCGGGCACACCCGAGCAGTCGACGCCGGACGAGGTGAACGCCGCACTGGATCGGCTGCTGATCG
CCGATGCGCTGGCCCAACTGTCCGCCGAGCATAGGGCCGTGATCCAGCGGTCCTACTACCGCGGATGGTC
GACCGCACAGATTGCCACCGACCTCGGAATTGCCGAAGGAACGGTGAAGTCGCGATTGCACTACGCCGTG
CGCGCGTTGCGGCTCACTCTGCAGGAACTGGGAGTTACTCGATG
Protein Sequence 
>gi|15607875|ref|NP_215249.1| ECF RNA polymerase sigma factor SigL [Mycobacterium tuberculosis H37Rv] MARVSGAAAAEAALMRALYDEHAAVLWRYALRLTGDAAQAEDVVQETLLRAWQHPEVIGDTARPARAWLFTVARNMIIDERRSARFRNVVGSTDQSGTPEQSTPDEVNAALDRLLIADALAQLSAEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRALRLTLQELGVTR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sigL mutant is attenuated in mice (Hahn et al., 2005).
COG COG1595K, under K: Transcription
References
Hahn et al., 2005: Hahn MY, Raman S, Anaya M, Husson RN. The Mycobacterium tuberculosis extracytoplasmic-function sigma factor SigL regulates polyketide synthases and secreted or membrane proteins and is required for virulence. Journal of bacteriology. 2005; 187(20); 7062-7071. [PubMed: 16199577].