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SP_0797

Victor ID 3237
Gene Name SP_0797
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930747
NCBI Protein GI 15900690
Locus Tag SP_0797
Protein Accession NP_345294.1
Other Database IDs UniProtKB-ID: Q97RK7_STRPN
UniRef100: UniRef100_A5LS61
UniRef90: UniRef90_C1CDF3
UniRef50: UniRef50_A2RI32
UniParc: UPI00000515B5
EMBL: AE005672
EMBL-CDS: AAK74934.1
RefSeq_NT: NC_003028.3
MEROPS: M01.002
EnsemblGenome: EBSTRG00000025433.
EnsemblGenome_TRS: EBSTRT00000025433
EnsemblGenome_PRO: EBSTRP00000024525
GenomeReviews: AE005672_GR
KEGG: spn:SP_0797
TIGR: SP_0797
HOGENOM: HBG515894
OMA: EYKAFFE
ProtClustDB: CLSK876725
BioCyc: SPNE170187-1:SP_0797-MONOMER
Taxonomy ID 170187
Gene Starting Position 749306
Gene Ending Position 751852
Gene Strand (Orientation) +
Protein Name aminopeptidase N
DNA Sequence 
>gi|194172857:749306-751852 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGCAAGCAGTTGAACATTTTATTAAGCAATTTGTTCCTGAACATTATGATTTATTTTTAGATTTGAGT
CGTGAGACCAAGACTTTTTCTGGGAAAGTGACCATCACTGGTCAAGCACAGAGTGACCGCATCTCCCTCC
ACCAAAAAGATTTGGAAATCACCTCTGTAGAAGTTGCAGGTCAAGCTCGTCCATTTACAGTTGACCATGA
CAATGAAGCCCTTCATATCGAATTGGCTGAGGCTGGTCAAGTTGAATTGGTTCTTGCCTTTTCTGGTAAA
ATTACAGACAACATGACAGGGATTTACCCTTCTTATTATACAGTTGATGGAGTCAAGAAGGAGGTCTTGT
CTACTCAGTTCGAGAGCCATTTTGCGCGCGAAGCTTTCCCATGTGTGGATGAGCCTGAAGCCAAAGCAAC
TTTTGACCTCTCTCTTCGCTTTGACCAAGCAGAAGGTGAATTGGCCTTGTCAAACATGCCAGAAATCGAT
GTTGAAAACCGTAAGGAAACAGGTATCTGGAAGTTTGAGACAACACCTCGCATGTCTTCTTACTTGTTGG
CCTTTGTTGCTGGTGATTTGCAAGGGGTGACCGCTAAAACTAAAAATGGTACCCTGGTAGGTGTCTACTC
AACCAAAGCACATCCACTTTCAAATCTTGATTTCTCACTGGATATCGCTGTTCGCTCTATCGAGTTTTAC
GAAGATTACTATGGAGTTAAGTACCCAATTCCTCAATCTCTCCACATCGCCCTTCCTGACTTCTCAGCTG
GTGCTATGGAAAACTGGGGTCTTGTGACCTACCGTGAAGTTTACTTGGTTGTCGATGAGAACTCTACATT
TGCTAGCCGTCAACAAGTTGCCCTTGTTGTGGCCCATGAATTGGCTCACCAATGGTTTGGGAACCTCGTG
ACTATGAAATGGTGGGATGACCTTTGGCTCAATGAAAGTTTCGCTAATATGATGGAATACGTCTGTGTGG
ATACCATCGAACCAAGCTGGAATATCTTTGAAGATTTCCAAACAGGTGGAGTACCTCTTGCTCTTGAACG
TGACGCTACTGATGGCGTTCAGTCTGTCCACGTCGAAGTTAAACATCCAGATGAAATCAATACACTCTTT
GACGGCGCTATCGTCTATGCCAAAGGAAGCCGTCTCATGCACATGCTTCGCCGTTGGCTAGGAGATGCTG
ATTTTGCTAAAGGTTTGCACGCCTACTTTGAAAAACACCAATACAGCAACACCATTGGTAGTGACCTTTG
GGATGCCCTTGGTCAAGCGTCAGGACGTGATGTCGCAGCCTTCATGGATTCTTGGTTGGAACAGCCTGGT
TACCCAGTTCTTACTGTTAAAGTTGAAAATGATGTCTTGAAGATTTCACAAAAACAATTCTTCATCGGTG
AGAACGAAGACAAGAACCGTCTCTGGGTGGTGCCCCTCAATAGCAACTGGAAAGGCTTGCCTGATACACT
CGAAACTGAAAGTATCGAAATCCCTGGCTACGCAGCTCTTCTTGCTGAAAATGAAGGAGCTCTTCGTCTC
AACACTGAAAATACTGCCCACTATATTACCGACTATCAAGGAGACTTGTTAGCAGCTGTTCTTGCTGAGC
TAGAGACACTTGATAACACAAGCAAACTGCAAATTGTTCAAGAACGTCGTTTGTTGGCTGAGGCAGGGCA
CATTTCTTATGCAGACTTGCTTCCAGTTCTTGATAAACTTGCTAAGGAAGAGTCTTATCTGGTGGTTTCA
GCTGTTTCTCAAGTGATTTCAGCCCTTGAGCGCTTTATTGATGAAGGAACGGATGCTGAAACAGCCTTCA
AAGGACTGGTTGCTAAATTGGCTCGTCATAACTATGACCGTCTTGGTTTTGAAGCTAAAGACGGAGAATC
AGATGAGGATGAATTGGTTCGTCAGCTGGCTGTTTCGATGATGATTCGCTCAAATGATGCAGAAGCTAGT
CAAGTCGCTAGCCAAATCTTCGCAACACACAAGGAGAATCTTGCAGGACTCCCAGCAGCTATTCGCTCAC
AAGTTCTGATTAATGAGATGAAACATCATGAGACTAAAGACTTGTTAGCACTTTATCTTGATACTTATAC
TCACGCAACAGATGCTGTCTTTAAACGCCAGTTGGCAGCAGCTCTTGCATACAGTACAGATGCGGATAAT
ATCCAAAACCTGATTACTTCTTGGAAGGACAAATTTGTGGTCAAACCACAGGACTTGTCTGCTTGGTATT
ACCAATTCCTAGCTCATCAAGCAACTCAGAAAACAGCTTGGTCTTGGGCGCGTGAAAACTGGGCTTGGAT
TAAGGCAGCCCTTGGAGGAGATATGAGCTTTGATAGCTTTGTTATCCTTCCTGCTCATGTATTTAAGACT
CAGCAACGCTTGGCGGAATACAAGGAGTTCTTTGAACCGCAACTTTCTGACCTTGCTCTTAGCCGTAACA
TCGGTATGGGAATCAAGGAAATTGCAGCGCGTGTTGACTTGATTAGCCGTGAAAAAGCTGCAGTCGAAGC
AGTTGTTCTTCAATACGGAAATGCATA
Protein Sequence 
>gi|15900690|ref|NP_345294.1| aminopeptidase [Streptococcus pneumoniae TIGR4] MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRISLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIYPSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMPEIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSNLDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDENSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWNIFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRWLGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVKVENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENEGALRLNTENTAHYITDYQGDLLAAVLAELETLDNTSKLQIVQERRLLAEAGHISYADLLPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFEAKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINEMKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQDLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLAEYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0797 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0308E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].