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clpP from Streptococcus pneumoniae TIGR4

Victor ID 3231
Gene Name clpP from Streptococcus pneumoniae TIGR4
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930696
NCBI Protein GI 15900641
Locus Tag SP_0746
Protein Accession NP_345245.1
Other Database IDs UniProtKB-ID: CLPP_STRPN
UniRef100: UniRef100_Q04LF4
UniRef90: UniRef90_Q1JDA9
UniRef50: UniRef50_Q8YQX8
UniParc: UPI000005157D
EMBL: AE005672
EMBL-CDS: AAK74885.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025854
EnsemblGenome_TRS: EBSTRT00000025854
EnsemblGenome_PRO: EBSTRP00000024946
GenomeReviews: AE005672_GR
KEGG: spn:SP_0746
TIGR: SP_0746
HOGENOM: HBG558421
OMA: SPMEAQD
ProtClustDB: PRK00277
BioCyc: SPNE170187-1:SP_0746-MONOMER
Taxonomy ID 170187
Gene Starting Position 706881
Gene Ending Position 707471
Gene Strand (Orientation) +
Protein Name ATP-dependent Clp protease proteolytic subunit
DNA Sequence 
>gi|194172857:706881-707471 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTC
AAAGACCGCATCATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGC
TTTTCTTGGATGCCCAAGATAGTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTC
AGCTGGTTTGGCAATCGTAGATACCATGAACTTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATG
GCTGCATCTATGGGGACTGTCATCGCATCAAGTGGAGCAAAAGGCAAACGTTTCATGCTTCCAAATGCTG
AATACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAAACTGATATGGCTATCGCTGC
AGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAGTCAATGGAA
AAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTG
ATGAAATTATGGCCAACAATTCATTGAACTA
Protein Sequence 
>gi|15900641|ref|NP_345245.1| ATP-dependent Clp protease proteolytic subunit [Streptococcus pneumoniae TIGR4] MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: clpP mutant is attenuated in mice (Ibrahim et al., 2005).
COG COG0740OU, under O: Posttranslational modification, protein turnover, chaperones; U: Intracellular trafficking, secretion, and vesicular transport
References
Ibrahim et al., 2005: Ibrahim YM, Kerr AR, Silva NA, Mitchell TJ. Contribution of the ATP-dependent protease ClpCP to the autolysis and virulence of Streptococcus pneumoniae. Infection and immunity. 2005; 73(2); 730-740. [PubMed: 15664911].