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SP_0726

Victor ID 3228
Gene Name SP_0726
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930676
NCBI Protein GI 15900623
Locus Tag SP_0726
Protein Accession NP_345227.1
Other Database IDs UniProtKB-ID: Q97RR7_STRPN
UniRef100: UniRef100_C1CQJ1
UniRef90: UniRef90_E0TLZ4
UniRef50: UniRef50_Q6G7L7
UniParc: UPI0000051568
EMBL: AE005672
EMBL-CDS: AAK74867.1
RefSeq_NT: NC_003028.3
HSSP: P55882
EnsemblGenome: EBSTRG00000026509.
EnsemblGenome_TRS: EBSTRT00000026509
EnsemblGenome_PRO: EBSTRP00000025601
GenomeReviews: AE005672_GR
KEGG: spn:SP_0726
TIGR: SP_0726
HOGENOM: HBG476673
OMA: LNIGHGH
ProtClustDB: PRK06427
BioCyc: SPNE170187-1:SP_0726-MONOMER
Taxonomy ID 170187
Gene Starting Position 690467
Gene Ending Position 691258
Gene Strand (Orientation) -
Protein Name phosphomethylpyrimidine kinase
DNA Sequence 
>gi|194172857:690467-691258 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CTTAATCTTTAAAAGTTGTATGGTTGACTGGACCAGAACCATGACCGAGTTGAGGGGCATCTTGAATAGC
TTTTGTGATAAAGGCCTTGGCCTTATCAACTGCCTGGTAAAGACTCTTGCCCTTGGCTAGTTCAGCAGTA
ATCACTGCAGCAAAGGTACATCCAGTACCATGGGTGTGACAGGTTTGAATTCGTGGGCTTTCCCAGACAA
ATTGTTCATTCTTGGTAAAGAGGAAATCTTTAGCACCACCTTTGAGATGTCCGCCTTTGATAACCACAGA
CTGAGGACCAAATTCTTTTAAAATCAGGCGACCAGCACGCTGCATGTCTTCGGGGTCATGGATTGAAAAA
CCAACAATCTCTTCTGCTTCAGGAAGATTTGGCGTAATAATAGTTGCTAGAGGTAGTAAGTTTGTTTTGA
GATAGTCTCTAGCATTTGAGTCAATCAAGGCATCTCCACTTGTAGCAACCATAACAGGATCAAGGACATA
GGGACAATCCAGTTTTTTAAGATAGGGTTGGATGATTTCCATGATTTCAGTAGTAGCCAACATTCCAGTT
TTTACAGCCTGAGGTGGAATATCAGAAAAGACACTCTCCAATTGGGCTTTCAACATTTGAGGAGAAACGT
GCTCGATTAGCTGAACACCTCTGGTATTTTGAGCGACAAGACTGGTTACAACAGCCATTCCATAGACATC
TCTCGCTTGGAATGACTTTAAATCTGCCATAATGCCAGCACCACCACTAGGGTCAGTCCCTGCAATGGTC
AAAGCAACGGGTAAATAAGTCA
Protein Sequence 
>gi|15900623|ref|NP_345227.1| phosphomethylpyrimidine kinase [Streptococcus pneumoniae TIGR4] MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVAQNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPYVLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRAGRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVITAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0736 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0351H, under H: Coenzyme transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].