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SP_0655

Victor ID 3219
Gene Name SP_0655
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930604
NCBI Protein GI 118090028
Locus Tag SP_0655
Protein Accession NP_345160.2
Other Database IDs UniProtKB-ID: Q97RX8_STRPN
UniRef100: UniRef100_B1RZN7
UniRef90: UniRef90_B5E2P8
UniRef50: UniRef50_Q5M2Z8
UniParc: UPI0000558285
EMBL: AE005672
EMBL-CDS: AAK74800.2
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025964.
EnsemblGenome_TRS: EBSTRT00000025964
EnsemblGenome_PRO: EBSTRP00000025056
GenomeReviews: AE005672_GR
KEGG: spn:SP_0655
TIGR: SP_0655
HOGENOM: HBG697820
ProtClustDB: CLSK697197
BioCyc: SPNE170187-1:SP_0655-MONOMER
Taxonomy ID 170187
Gene Starting Position 625663
Gene Ending Position 627717
Gene Strand (Orientation) +
Protein Name sodium/hydrogen exchanger family protein
DNA Sequence 
>gi|194172857:625663-627717 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CGTGGAATTACTGATTTACCTCATCCTATTTTTACTGGTTTTGATTGTCTCAAGTACAACCAATAAGCTC
CTGCCCTTTTTGCCTCTCCCTTTGGTGCAAATTCTTTTGGGAATTGTGATTGGTCTCTTTTTACCCAATA
CTGACTTTCACCTTAATACGGAGTTGTTTTTGGCACTGGTTATCGGACCCTTGCTTTTCCGAGAGGCTGA
AGAAGCAGATGTTACGGCTATTTTAAAACACTGGCGAATCATTGTTTATCTCATATTTCCAGTGATTTTT
ATCTCGACCCTGAGTTTGGGTGGCTTGGCCCATCTTCTTTGGTTCAGCCTTCCCTTGGCAGCTTGCTTGG
CTGTTGGGGCAGCCCTTGGTCCTACGGACTTGGTGGCCTTTGCCTCTCTTTCGGAGCGTTTTAGCTTTCC
TAAGCGCGTGTCCAATATTCTTAAGGGCGAAGGACTCTTGAATGATGCTTCTGGTTTGGTGGCTTTTCAG
GTAGCTTTGACAGCTTGGACAACTGGAGCTTTTTCTCTGGGGCAAGCTAGCAGTTCGCTCATCTTTTCAA
TCCTAGGCGGTTTTTTAATTGGATTTTTAACAGCCATGACCAACCGCTTCCTCCATACCTTCTTGCTAAG
TGTGCGCGCAACGGATATTGCCAGTGAACTTTTATTAGAATTGAGTTTGCCTCTAGTGACCTTCTTTCTG
GCAGAAGAAGTTCATGTTTCAGGTATTATTGCCGTCGTAGTTGCTGGAATTTTAAAGGCAAGTCGCTTCA
AGAAAATCACGCTCCTCGAAGCCCAAGTGGATACGGTGACCGAGACGGTCTGGCATACAGTGACCTTTAT
GCTCAACGGTTCTGTCTTTGTGATTTTAGGGATGGAGTTGGAAATGATAGCAGAACCTATCTTGACCAAT
CCAATCTATAATCCTCTACTTTTATTGCTATCTCTTATCGCCCTTACCTTTGTCCTTTTTGTCATTCGTT
TTATTATGATCTATGGCTATTATGCCTATAGAACCCGACGCCTCAAGAAAAAGCTAAATAAGTATATGAA
GGACATGTTTCTCTTGACCTTTTCAGGTGTTAAGGGAACGGTGTCGATTGCTACGATTCTCTTGATACCA
AGTAATCTAGAACAGGAGTATCCTCTTTTGCTTTTCCTTGTTGCAGGTGTGACGCTTGTTAGCTTTTTAA
CAGGTCTCTTGGTCTTGCCTCATCTTTCTGATGAAGAGGAAGAAAGCAAGGATTATCTTATGCATATCGC
CATTTTGAATGAAGTAACGCTAGAGTTGGAAAAAGAGTTGGAAGACACCAGAAATAAACTTCCCCTCTAT
GCGGCTATTGACAATTATCATGGACGTATTGAAAATCTCATTTTAAGCCAAGAAAACCAGGATGATCAAG
AAGACTGGGCTGCTTTGAAACTCTTGATTCTTAGTATTGAAAGTGATGGTTTGGAACAGGCCTATGAAGA
GGGGAACATTAGCAATCGTGCTTACCGAGTTTACCAACGTTATCTGAAAAATATAGAACAAGGAATCAAT
CGTAAACTTGCCTCAAGACTGACCTATTATTTTCTTGTTTCCTTGAGGATTTTACGTTTTCTCCTTCATG
AAGTTTTTACTCTCGGAAAGACCTTCCGTAGCTGGAAGAACAAGGAGCAAAGCCGTCTCCGTGCTCTTGA
TTATGACCAAATTGCAGAGCTCTATCTTGCCAATACAGAGATGATTATTGAAAGTTTGGAAAACCTGAAG
GGAGTCTACAGACGCTCTTTGATTAGTTTTATGCAGGAGTCTCGTCTTCGAGAAACAGCTATTATCAGCA
GTGGTGCCTTTGTCGAACGGGTTATCAATCGTGTCAAACCCAACAATATCGATGAAATGCTGAGAGGCTA
TTATCTGGAGCGCAAGTTGATTTTCGAATACGAAGAAAAACGATTGATTACGACTAAGTATGCCAAGAAA
TTACGACAAAATGTAAATAACTTAGAGAACTATTCCTTGAAGGAAGCTGCCAATACCCTACCGTATGATA
TGGTGGAATTGGTAAGAAGAAATTA
Protein Sequence 
>gi|118090028|ref|NP_345160.2| sodium/hydrogen exchanger family protein [Streptococcus pneumoniae TIGR4] MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFLPNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGLAHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLVAFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIASELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHTVTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYYAYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTLVSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYHGRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNIEQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAELYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNIDEMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVRRN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0655 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0025P, under P: Inorganic ion transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].