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SP_0622

Victor ID 3214
Gene Name SP_0622
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930571
NCBI Protein GI 15900530
Locus Tag SP_0622
Protein Accession NP_345134.1
Other Database IDs UniProtKB-ID: Q97S03_STRPN
UniRef100: UniRef100_Q97S03
UniRef90: UniRef90_C1CJ93
UniRef50: UniRef50_Q5XCB9
UniParc: UPI00000514F9
EMBL: AE005672
EMBL-CDS: AAK74774.1
RefSeq_NT: NC_003028.3
PDB: 2B67
EnsemblGenome: EBSTRG00000025896.
EnsemblGenome_TRS: EBSTRT00000025896
EnsemblGenome_PRO: EBSTRP00000024988
GenomeReviews: AE005672_GR
KEGG: spn:SP_0622
TIGR: SP_0622
HOGENOM: HBG697552
OMA: NIQDWRI
ProtClustDB: CLSK876698
BioCyc: SPNE170187-1:SP_0622-MONOMER
Taxonomy ID 170187
Gene Starting Position 589566
Gene Ending Position 590171
Gene Strand (Orientation) +
Protein Name nitroreductase family protein
DNA Sequence 
>gi|194172857:589566-590171 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGAAATTTCTTGAATTAAATAAAAAACGTCATGCGACTAAGCATTTTACTGATAAGCTTGTTGATCCC
AAAGATGTGCGTACGGCTATCGAAATTGCAACCTTGGCGCCAAGCGCCCACAACAGCCAGCCTTGGAAAT
TTGTGGTGGTACGTGAGAAAAATGCTGAACTGGCAAAGTTAGCTTATGGTTCCAATTTTGAACAGGTATC
ATCAGCGCCTGTAACCATTGCCTTGTTTACAGATACGGACTTAGCCAAACGTGCTCGTAAGATTGCCCGT
GTTGGTGGTGCTAATAACTTTTCTGAAGAGCAACTTCAATATTTTATGAAAAATCTGCCAGCTGAGTTTG
CCCGTTACAGTGAGCAACAAGTCAGCGACTACCTAGCTCTCAATGCAGGTTTGGTTGCCATGAACTTGGT
TCTTGCATTGACAGACCAAGGAATTGGTTCTAACATTATTCTTGGTTTTGACAAATCAAAAGTTAATGAA
GTTTTGGAAATCGAAGACCGTTTCCGCCCAGAACTCTTGATCACAGTGGGTTATACAGACGAAAAATTGG
AACCAAGCTACCGCTTGCCAGTAGATGAAATCATCGAGAAAAGATA
Protein Sequence 
>gi|15900530|ref|NP_345134.1| nitroreductase [Streptococcus pneumoniae TIGR4] MKFLELNKKRHATKHFTDKLVDPKDVRTAIEIATLAPSAHNSQPWKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSEEQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSKVNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0622 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0778C, under C: Energy production and conversion
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].