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SP_0510

Victor ID 3207
Gene Name SP_0510
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930448
NCBI Protein GI 15900424
Locus Tag SP_0510
Protein Accession NP_345028.1
Other Database IDs UniProtKB-ID: Q97S78_STRPN
UniRef100: UniRef100_Q97S78
UniRef90: UniRef90_Q04LY5
UniRef50: UniRef50_B2IMB0
UniParc: UPI000005147D
EMBL: AE005672
EMBL-CDS: AAK74668.1
RefSeq_NT: NC_003028.3
REBASE: 5713
EnsemblGenome: EBSTRG00000025993.
EnsemblGenome_TRS: EBSTRT00000025993
EnsemblGenome_PRO: EBSTRP00000025085
GenomeReviews: AE005672_GR
KEGG: spn:SP_0510
TIGR: SP_0510
HOGENOM: HBG295251
OMA: QTCKLIV
ProtClustDB: CLSK803719
BioCyc: SPNE170187-1:SP_0510-MONOMER
Taxonomy ID 170187
Gene Starting Position 491795
Gene Ending Position 494128
Gene Strand (Orientation) -
Protein Name type I restriction-modification system, R subunit
DNA Sequence 
>gi|194172857:491795-494128 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATTAAGCTACTGTAAATAGCTCTTGCTCCAATTCTTTAATTGCTTGTAAATATCGTTTTTTATCTCCAAA
ATAAGTATTGATGATTTTGAAGGTTCCACCATATATCTGAAATTCTGGAAGTTTTAATGTTTCAATGCTT
TCGAGTTCTCCAATACCTTTATCCATGTATTTGTTCAGTAAAATTTCCAAAACAGCACGCGCTTCCTCAC
TATATTTATATAAATATCCGCTTTGTTTGAGTTTATTGATACGTTCCGTTTTGGTTAATTCTTTTTGACC
ATAGGCAAGTTTTAGGAGTAAATCAAAATCATCGATTTCTTGTTCTGATATTCCCTCCGACTCTCGAATA
GCATCTAGATAAACTCCTTTTTTATAAAGTTCGTCTAAGATAAGCTTCTTCTTATCTGCCGTATGCCAAA
CTGTGATAAAATCGTTCAAAGTGGCGTAGCTACCTAAGATATTCTTTCGAGTGTAGTCGGTCAGGCTTTC
GGTAATCAGTTTCCCGTTTTCATCCAATACTTGAACAGTAGAATTAAGAATGGTAACCTGCTTGTCTGTA
ACGATATATTTTTCTACTGGGTCACCTTCCTCATCTACGAAACCGGGCGTAGAACCACTGACTGTTTTCG
CACCTGTTTCTAGCACCTTCACTGGATCACCATCAAAATCAGGGTCAGCAAACAAATTGGTAACATTTCG
AAAATCAATAATCGTAAAAAATTCTTTCCCCTTTTGAGGATAAAGACGTGTGCCACGACCAATAATTTGT
TTAAATTCAGTCATGGATTGGATATTAGAGTCTAAAACAATCAAACGACATGTTTTAGCATTAACTCCTG
TCGTTAATAATTTAGACGTTGTTACAATAGCGGGAAAATTAGAATTGACATCCATAAAGTTATCCAGTTG
AGCTTTTCCTTCAGCGTTGTCACCAGTTACTTGCATGACATAACGATAGTCTTCTTGGACTAAGTCTAGA
TTCTCTTTTACAAGTGCAGCACGCATTCGCTCGGCATGGTCAATATCAACACAAAAAACAATTGTTTTAT
CAAATCGTGCATTGTTTTGCTTCATATAATCAGAAACAAACTTGGCAACTCTTTGCGTTCTATCATCAAT
GACAATGGTTTTATCAAAATCTTTCCTGCCGTAGTACCTATCTTCTATTAATTGTCCGTTAGCATCAACT
TTTCCAGTTTCTGGACGATAACCATCCACATCCACATCTAAATTAACCCTCATAACACGATATGGAGCCA
AAAAACCATCCTCGATTCCCTGTTTTAAACTATAAGTATAGATTGGCTCACCAAAGTATTCCGTATTGGA
AGCATTCTTGGTTTCTTTAAGAGTAGCGGTCATCCCAATCTGTGTCGCAGAACTGAAATAATCAATTACC
TTACGCCAGTTACTGTTTTCCTTAGCTGAACCACGGTGCGCTTCATCAATTACGATTAAATCAAAGAAGT
CTTTGTCAAATTTTTGATAATGTGTTTCAGTTCCATCTTCACCAGTTAGTTGCTGATAAAGCCCTAGATA
AATTTCAAAAGAATTTAATTTTTCAGGAGCAGTCAAAAGTTTTGGTGTAATTTTCGTCATTACCTTTTCG
AATGGCCTAAAGTCTTCAGCCATCGTTTGGTCTACTAAGATGTTTCTATCTGCTAAGAATAAAACTCGTT
TAGCCAAACCAGCTTTTCGAAGGCGATGAATAATTTGAAAAGCCATGAACGTTTTCCCCGTTCCTGTTGC
CATCACAAACATTACTCGTTTTTGTCCTCTGGCAACTGTTTCAATAGTACGGTTGATAGCTATTTGCTGA
TAATAGCGTGGCGTTTTCATTGAGAAGGCGTCTGTATAGTATGGAGTTGAGATAGCTTCTGTAATTTCGT
ACGTCAATCCTTTTTCCTTCGTCATACGAGAAAATAATTCTTCACGAGTAGGGAATTCGTCTAACTCCAG
CTCACGTTCTTCTCTCGTGATACGGTCGTGTTCAATAAAGCCATCACCATTCGAAGAATAAACAAATGGA
ACATCTAAAATCTCTCCATATTCAATAGCTTGTTGTAATCCTGCTCGAACGCTGTGTTTATTATCCTTTG
CCTCAACAATTGCAATTCGAGTTCCAAATTGGTAATACAGTGAATAGTCTGATTTTTTTCCTTCTTTACG
ACGAGCCTTATCTCCTCTAACTTCAATTCGACCATCAGTGAAGTATTCTTCGTAAGCGATATGCTCACCA
TTTTTCCATCCTTTGGATACAATAGCAGGAGTGATGAAATTTGCTTTAATATCCTCCTCACTCATTTCTT
TCTTAGACTTTATAAACTCAACCA
Protein Sequence 
>gi|15900424|ref|NP_345028.1| type I restriction-modification system, R subunit [Streptococcus pneumoniae TIGR4] MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYYTDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATLKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0510 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG4096V, under V: Defense mechanisms
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].