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SP_0494

Victor ID 3205
Gene Name SP_0494
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930432
NCBI Protein GI 15900408
Locus Tag SP_0494
Protein Accession NP_345012.1
Other Database IDs UniProtKB-ID: PYRG_STRPN
UniRef100: UniRef100_Q97S93
UniRef90: UniRef90_Q8DQY0
UniRef50: UniRef50_A8YXF8
UniParc: UPI000005146E
EMBL: AE005672
EMBL-CDS: AAK74652.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026570
EnsemblGenome_TRS: EBSTRT00000026570
EnsemblGenome_PRO: EBSTRP00000025662
GenomeReviews: AE005672_GR
KEGG: spn:SP_0494
TIGR: SP_0494
HOGENOM: HBG597806
OMA: RVTMQKL
ProtClustDB: PRK05380
BioCyc: SPNE170187-1:SP_0494-MONOMER
Taxonomy ID 170187
Gene Starting Position 470730
Gene Ending Position 472337
Gene Strand (Orientation) +
Protein Name CTP synthase
DNA Sequence 
>gi|194172857:470730-472337 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGTCTACGAAATATATTTTTGTAACTGGTGGTGTGGTATCGTCCATTGGGAAAGGGATTGTGGCAGCG
AGTCTAGGCCGTCTCTTGAAAAATCGTGGTCTCAAAGTAACCATTCAAAAGTTTGACCCTTATATCAATA
TTGATCCGGGAACCATGAGTCCTTACCAGCACGGGGAAGTTTTTGTGACAGATGACGGAGCTGAGACAGA
TTTGGACTTGGGTCACTATGAACGTTTCATCGATATCAATCTCAACAAATATTCCAACGTGACAACTGGG
AAAATTTACAGTGAAGTTCTTCGTAAAGAACGCCGTGGAGAATACCTTGGGGCAACTGTTCAAGTCATTC
CTCATATCACAGATGCTTTGAAAGAAAAAATCAAGCGTGCCGCTCTAACGACCGACTCTGATGTCATTAT
CACAGAGGTTGGTGGAACAGTAGGAGATATCGAGTCCTTGCCATTCCTAGAGGCTCTTCGTCAGATGAAG
GCAGATGTGGGTGCGGATAATGTCATGTATATCCATACAACCTTGCTTCCTTACCTCAAGGCTGCTGGTG
AAATGAAAACCAAACCAACCCAACACTCTGTCAAAGAATTGCGTGGCTTGGGAATCCAACCAAATATGTT
GGTTATTCGTACAGAAGAGCCAGCTGGTCAAGGAATTAAAAATAAACTGGCCCAGTTCTGTGATGTGGCA
CCAGAAGCCGTTATCGAATCGTTGGATGTTGAACACCTTTACCAAATTCCACTGAACTTGCAGGCACAAG
GGATGGACCAAATTGTTTGTGATCATTTGAAATTAGACGCACCAGCAGCGGATATGACAGAATGGTCAGC
CATGGTGGACAAGGTCATGAACCTCAAGAAACAAGTTAAGATTTCCCTTGTTGGTAAGTATGTGGAGTTG
CAAGATGCCTATATCTCAGTGGTCGAAGCCTTGAAACACTCTGGCTATGTCAATGATGCAGAAGTTAAAA
TCAATTGGGTCAATGCCAATGATGTGACAGCAGAGAATGTAGCAGAACTCTTGTCTGATGCGGACGGGAT
CATCGTACCAGGTGGTTTTGGTCAACGTGGTACAGAAGGGAAAATCCAAGCCATCCGCTATGCGCGTGAA
AATGATGTTCCAATGTTGGGAGTCTGCTTGGGAATGCAGTTGACATGTATCGAGTTTGCTCGTCACGTTT
TAGGTCTTGAAGGTGCCAATTCTGCAGAGCTTGCACCAGAAACAAAATACCCTATCATTGATATCATGCG
TGATCAGATTGATATTGAGGATATGGGTGGAACCCTTCGTTTGGGACTTTATCCGTCTAAGTTGAAACGT
GGCTCTAAGGCTGCTGCTGCTTATCACAATCAAGAAGTGGTGCAACGCCGTCACCGTCACCGTTATGAGT
TTAATAATGCCTTCCGTGAGCAGTTTGAGGCAGCAGGTTTTGTCTTTTCAGGAGTTTCTCCAGACAATCG
TTTGGTAGAAATCGTGGAAATTCCTGAAAATAAATTCTTTGTAGCTTGTCAGTATCACCCTGAACTGTCA
AGCCGTCCAAACCGACCAGAAGAACTCTACACTGCCTTTGTTACTGCAGCAGTTGAGAACAGCAATTA
Protein Sequence 
>gi|15900408|ref|NP_345012.1| CTP synthetase [Streptococcus pneumoniae TIGR4] MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALRQMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPAGQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMTEWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNANDVTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEFARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAAYHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQYHPELSSRPNRPEELYTAFVTAAVENSN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0494 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0504F, under F: Nucleotide transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].