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SP_0478

Victor ID 3202
Gene Name SP_0478
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930416
NCBI Protein GI 15900393
Locus Tag SP_0478
Protein Accession NP_344997.1
Other Database IDs UniProtKB-ID: Q97SA8_STRPN
UniRef100: UniRef100_A5LK37
UniRef90: UniRef90_E0TSM1
UniRef50: UniRef50_B5E1T1
UniParc: UPI000005145C
EMBL: AE005672
EMBL-CDS: AAK74637.1
RefSeq_NT: NC_003028.3
PDB: 3NBM
EnsemblGenome: EBSTRG00000026127.
EnsemblGenome_TRS: EBSTRT00000026127
EnsemblGenome_PRO: EBSTRP00000025219
GenomeReviews: AE005672_GR
KEGG: spn:SP_0478
TIGR: SP_0478
HOGENOM: HBG337916
OMA: NDIILEE
ProtClustDB: CLSK877288
BioCyc: SPNE170187-1:SP_0478-MONOMER
Taxonomy ID 170187
Gene Starting Position 457342
Gene Ending Position 459021
Gene Strand (Orientation) +
Protein Name PTS system, lactose-specific IIBC components
DNA Sequence 
>gi|194172857:457342-459021 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGGATAAGCTAGTCGCTGCCATTGAAAAGCAACAAGGGAAATTTGAAAAAATTTCTACTAATAACTAT
ATGATGGCTATTAAAGATGGATTCATTGCTACTATGCCTTTAATTATGTTTTCAAGCTTTTTGATGATTA
TTATTATGATTCCTAAAAATTTCGGAGTAGAGTTACCGAGTCCAGCTATTGTCTGGATGAGAAAAGTGTA
TATGTTAACCATGGGAGTTTTGGGTATTATTGTTTCAGGGACTGTTGGAAAGTCATTAGTTGGAAATGTT
AACAGAAAAATGCCTCACGGAAAGGTAATAAATGATATTTCTGCAATGTTGGCAGCCATATGTAGTTATC
TGGTATTAACTGTAACGCTTGTAGTTGATGAGAAGACGGGATCTACAAGTTTGTCGACAAACTATTTAGG
ATCTCAAGGATTGATAACTTCGTTTGTCAGTGCCTTTATTACTGTAAATGTTTACCGATTCTGTATTAAG
CGAGACATTACTATTCATTTACCTAAGGAAGTTCCTGGGGCTATATCACAAGCTTTTAGAGATATTTTCC
CTTTTTCTTTTGTTTTACTTATTAGTGGTTTGTTAGATATTGTATCTCGGTTTAGTTTAGATGTTCCTTT
TGCCCAAGTATTTCAACAACTATTGACTCCTATTTTTAAGGGGGCAGAATCATATCCTGCTATGATGTTG
ATTTGGTTTATGTGTGCTTTGCTTTGGTTTGTTGGAATTCATGGACCATCTATTGTCTTACCTGCTGTTA
CAGCTTTGCAACTGAGCAATATGGAAGAGAATGCTCAACTTCTTGCAAATGGGCAGTTCCCTTATCATTC
TTTAACACCTAATTTCGGGAATTATATCGCTGCTATTGGAGGAACGGGGGCTACCTTTGTTGTACCATTT
ATTTTGATTTTCTTTATGCGGTCTAAACAATTAAAATCGGTAGGTAAAGCTACAATTACTCCTGTTTTAT
TTGCGGTAAATGAACCTCTTCTATTTGGTATGCCTGTTATTTTGAATCCCTATCTTTTTGTCCCTTTTTT
GATGACTCCACCAGTGAATGTATTTCTAGGAAAGGTCTTTATTGATTTCTTTGGAATGAATGGATTTTAT
ATCCAGTTACCTTGGACCTTTCCTGGTCCCTTGGGATTGTTAATTGGAACGAATTTTCAACTTATCTCCT
TTGTATTTTTATCTTTGATTTTAGTTGTCGACATATTGATTTATTTGCCATTCTGTAGAGCGTATGATAG
ACAGTTACTGGTGAAAGAAGATATTGCAAGCTCAAATGATATTATTTTAGAGGAGGATACAAGTGAAATA
ATTCCTGGTGAGATAGATGAAATAAAAAGTAAGGAGTTGAAAGTACTGGTTCTTTGTGCAGGGTCTGGAA
CAAGTGCGCAATTAGCCAATGCAATTAACGAGGGGGCTAACTTAACAGAGGTTAGAGTGATTGCGAATTC
AGGAGCGTACGGAGCTCATTATGATATTATGGGTGTTTATGATTTAATTATTCTGGCCCCACAAGTTCGG
AGTTATTATAGAGAGATGAAGGTGGATGCAGAAAGATTAGGTATTCAGATAGTTGCTACCAGAGGAATGG
AATATATTCATTTAACAAAGAGTCCAAGTAAAGCCTTACAATTTGTATTGGAGCATTACCAAGCTGTGTA
Protein Sequence 
>gi|15900393|ref|NP_344997.1| PTS system lactose-specific transporter subunit IIBC [Streptococcus pneumoniae TIGR4] MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFLMIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKVINDISAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRFCIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLLTPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQFPYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLLFGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWTFPGPLGLLIGTNFQLISFVFLSLILVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIIPGEIDEIKSKELKVLVLCAGSGTSAQLANAINEGANLTEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0478 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1455G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].