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SP_0468

Victor ID 3200
Gene Name SP_0468
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930406
NCBI Protein GI 15900384
Locus Tag SP_0468
Protein Accession NP_344988.1
Other Database IDs UniProtKB-ID: Q97SB7_STRPN
UniRef100: UniRef100_D6ZQV3
UniRef90: UniRef90_B1I9Q9
UniRef50: UniRef50_B1I9Q9
UniParc: UPI0000051450
EMBL: AE005672
EMBL: EF560626
EMBL: EF560627
EMBL: EF560628
EMBL: EF560630
EMBL: EF560637
EMBL-CDS: AAK74628.1
EMBL-CDS: ABS82083.1
EMBL-CDS: ABS82090.1
EMBL-CDS: ABS82097.1
EMBL-CDS: ABS82111.1
EMBL-CDS: ABS82160.1
RefSeq_NT: NC_003028.3
PDB: 2W1K
MEROPS: C60.001
EnsemblGenome: EBSTRG00000026228.
EnsemblGenome_TRS: EBSTRT00000026228
EnsemblGenome_PRO: EBSTRP000000253
Taxonomy ID 170187
Gene Starting Position 446563
Gene Ending Position 447414
Gene Strand (Orientation) +
Protein Name sortase, putative
DNA Sequence 
>gi|194172857:446563-447414 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CATGTCAAGGACTAAACTACGAGCCTTATTGGGATACTTGTTGATGTTGGTAGCCTGTTTGATTCCTATT
TATTGTTTTGGACAGATGGTGTTGCAGTCTCTTGGACAGGTGAAAGGTCATGCTACATTTGTGAAATCCA
TGACAACTGAAATGTACCAAGAACAACAGAACCATTCTCTCGCCTACAATCAACGCTTGGCTTCGCAAAA
TCGCATTGTAGATCCTTTTTTGGCGGAGGGATATGAGGTCAATTACCAAGTGTCTGACGACCCTGATGCA
GTCTATGGTTACTTGTCTATTCCAAGTTTGGAAATCATGGAGCCGGTTTATTTGGGAGCAGATTATCATC
ATTTAGGGATGGGCTTGGCTCATGTGGATGGTACACCGCTGCCTCTGGATGGTACAGGGATTCGCTCAGT
GATTGCTGGGCACCGTGCAGAGCCAAGCCATGTCTTTTTCCGCCATTTGGATCAGCTAAAAGTTGGAGAT
GCTCTTTATTATGATAATGGCCAGGAAATTGTAGAATATCAGATGATGGACACAGAGATTATTTTACCGT
CGGAATGGGAAAAATTAGAATCGGTTAGCTCTAAAAATATCATGACCTTGATAACCTGCGATCCGATTCC
TACCTTTAATAAACGCTTATTAGTGAATTTTGAACGAGTCGCTGTTTATCAAAAATCAGATCCACAAACA
GCTGCAGTTGCGAGGGTTGCTTTTACGAAAGAAGGACAATCTGTATCGCGTGTTGCAACCTCTCAATGGT
TGTACCGTGGGCTAGTGGTACTGGCATTTCTGGGAATCCTGTTTGTTTTGTGGAAGCTAGCACGTTTACT
ACGAGGGAAATA
Protein Sequence 
>gi|15900384|ref|NP_344988.1| sortase [Streptococcus pneumoniae TIGR4] MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFVKSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPSLEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLKVGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLVNFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKLARLLRGK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0468 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG3764M, under M: Cell wall/membrane/envelope biogenesis
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].