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ipaB from Shigella flexneri 5a

Victor ID 32
Gene Name ipaB from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876451
NCBI Protein GI 13449074
Locus Tag pWR501_p135
Protein Accession NP_085290.1
Other Database IDs UniProtKB-ID: IPAB_SHIFL
UniRef100: UniRef100_P18011
UniRef90: UniRef90_Q03945
UniRef50: UniRef50_P18011
UniParc: UPI000012D7D2
EMBL: J04117
EMBL: M34849
EMBL: AL391753
EMBL: AF348706
EMBL: X15319
EMBL: AF386526
EMBL-CDS: AAA26522.1
EMBL-CDS: AAA98424.1
EMBL-CDS: CAC05803.1
EMBL-CDS: AAK18446.1
EMBL-CDS: CAA33381.1
EMBL-CDS: AAL72352.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
PDB: 3GZ1
PDB: 3GZ2
EnsemblGenome: EBESCG00000093197
EnsemblGenome_TRS: EBESCT00000094153
EnsemblGenome_PRO: EBESCP0
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 104272
Gene Ending Position 106014
Gene Strand (Orientation) -
Protein Name invasion protein
DNA Sequence 
>gi|13448939:104272-106014 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
ATCAAGCAGTAGTTTGTTGCAAAATTGCTTTTGCAACATCAGTTCTATTAGCCTGAGAGTTGGACATTGA
GGCTAATAGATCTGCAATTACTTCCTGCAATTGGCCGAATTTTTCTATTGCTTCACTGATATATTTTGAC
AGTTGTTCAACTTGATATTTCGATAATGTCAGGTCTGCTAGATTTGTCGACGCGCTGTTCTGGAAAACAG
CAGAAGCGACACTTCCTCCCGCTTGTGTGGCAGAGTTAACACTTTCTCCTAATAAAACTGCTTGGTTTAA
ATGGGTGGAAATAATTTGTTTGGATATTACTTCATCACCCGCTGCACCAAGAAATTTATTTAATCTGGCA
ACAGCATTAGTGATTAAATCGTCCAGTTGAGAAGAAAAATTCTTGAGAAACTTTGGTATAAGGTCTGTGA
GGGTTTTACCTATTATTTTGCCAATATTTTCTGCAAGTTTTGCTGCTGCCTGTTTACCAACAGTGGCTAC
GAGAACGACTGCTGCAACTAGGACAAGAGCGCCTGCGATTGCCCCCAGAATAGAGCCAATCATTTTGGCT
TTTTTCGAGTCGACGCCCAAGCCTTCGAGCATTTTTGTAAATGCATCTGAAAGGAGTTTGATTAAGGGTT
CAATGACTGCTTTCATGATCGGATTCAGGGCTTGTTCCATGAAGGAATTGCCGGTCGCTGCTTGTACTAT
AGCATCCGTAACCATAAGAGCTAAACCAACAGCTGCCAGTGCTAGAGAGGCTCCTCCAGAAAAAGCTGCT
GCAACAACACTAACGATAGTTAAAAGTGCCCCAAGTATTTTCCCAACACAACCCATTACTCTGTTGAGTT
CTTCTGCTTTACGTACTTCAGCAGCATACTCATCAGATTTTCTCTCCATTTCAGTTTTTCTTGATTCTTG
GAGAGACTGGAATAGAGCCAGATCATTTTTTAAAGATTCTTCATTATTTTTTCCAACTAGTTGAATAAAG
GTTGCCATCAATTGAGTAACACTGGCAAGTCCGGTTAATGATTTCTGCTGGGTTGATAGCTGTTCAGCAG
ATGCTGTGTTTGAAAATGCAGAAAAAGAGTCTATTTCTTTTTCGAGTTGCATTGATTTATCTGTAAGTTT
GCTATGAATTGACAGGGTTTTCTGCTCAATCAATGTCCTGTCTTTAACTGCTGCGTCTTTTTTGATAGTG
AGTTGTATTTCTTCCCGGCTTAATTTTTTCTTTTCTGGTGACTCTGGATCGAGTTCGGATAATCTTGTTT
GAATTTGGTTAATTTTATTTTCTAGGTCTTTTATTTTAGAATCTGCGTTTTTTAGTTTATTAATTTGTTT
TTCATAGTCTCTGGTTAGTCCTTCAGTTTCAGATAGAAGAGTGTTAATTTTATCGGAGAATTCTAGGTTT
TTTTGCTGTCTTGCCTGTTGCTGGGACTTCCAAGCAGTAATTTTATTTGTTAATGCAGTTAAAGATTTTT
CACCGAGTATTTGAATAAGGTTTCCAATTAAAAGCGTTAGTTGGGAACTTGCATTTAATGACTTTGGTGC
TTTAAGTTCAGGGATTAATATATTTGAAGTTGAGTGTGCATTAGTTGTATTAATATTTTGGTTAGCAGTA
AGATCAGCAATTGTAAGAGAAAATAATTTGTTAGCTGCATCATTTGCAGCTTGGATAGTATTGTCTCCAA
GCTCAGTGGAAGTCAATATTTTGGCAAGAGGAAAACCAGTGGTTGTGGTGCTTACATTATGCA
Protein Sequence 
>gi|13449074|ref|NP_085290.1| invasion protein [Shigella flexneri 5a str. M90T] MHNVSTTTTGFPLAKILTSTELGDNTIQAANDAANKLFSLTIADLTANQNINTTNAHSTSNILIPELKAPKSLNASSQLTLLIGNLIQILGEKSLTALTNKITAWKSQQQARQQKNLEFSDKINTLLSETEGLTRDYEKQINKLKNADSKIKDLENKINQIQTRLSELDPESPEKKKLSREEIQLTIKKDAAVKDRTLIEQKTLSIHSKLTDKSMQLEKEIDSFSAFSNTASAEQLSTQQKSLTGLASVTQLMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKAEELNRVMGCVGKILGALLTIVSVVAAAFSGGASLALAAVGLALMVTDAIVQAATGNSFMEQALNPIMKAVIEPLIKLLSDAFTKMLEGLGVDSKKAKMIGSILGAIAGALVLVAAVVLVATVGKQAAAKLAENIGKIIGKTLTDLIPKFLKNFSSQLDDLITNAVARLNKFLGAAGDEVISKQIISTHLNQAVLLGESVNSATQAGGSVASAVFQNSASTNLADLTLSKYQVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQANRTDVAKAILQQTTA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ipaB mutant is unable to infect HeLa cells (Roehrich et al., 2010).
References
Roehrich et al., 2010: Roehrich AD, Martinez-Argudo I, Johnson S, Blocker AJ, Veenendaal AK. The extreme C terminus of Shigella flexneri IpaB is required for regulation of type III secretion, needle tip composition, and binding. Infection and immunity. 2010; 78(4); 1682-1691. [PubMed: 20086081].