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SP_0454

Victor ID 3198
Gene Name SP_0454
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930392
NCBI Protein GI 15900371
Locus Tag SP_0454
Protein Accession NP_344975.1
Other Database IDs UniProtKB-ID: Q97SD0_STRPN
UniRef100: UniRef100_Q97SD0
UniRef90: UniRef90_Q04M25
UniRef50: UniRef50_Q04M25
UniParc: UPI0000051442
EMBL: AE005672
EMBL-CDS: AAK74615.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026344.
EnsemblGenome_TRS: EBSTRT00000026344
EnsemblGenome_PRO: EBSTRP00000025436
GenomeReviews: AE005672_GR
KEGG: spn:SP_0454
TIGR: SP_0454
HOGENOM: HBG702632
OMA: RRKTTPS
ProtClustDB: CLSK625812
BioCyc: SPNE170187-1:SP_0454-MONOMER
Taxonomy ID 170187
Gene Starting Position 426441
Gene Ending Position 428333
Gene Strand (Orientation) +
Protein Name hypothetical protein
DNA Sequence 
>gi|194172857:426441-428333 Streptococcus pneumoniae TIGR4 chromosome, complete genome
GTTGATGAAAAAAACTTTTTTCTTACTGGTGTTAGGCTTGTTTTGCCTTCTTCCACTCTCTGTTTTTGCC
ATTGATTTCAAGATAAACTCTTATCAAGGGGATTTGTATATTCATGCAGACAATACGGCAGAGTTTAGAC
AGAAGATAGTTTACCAGTTTGAGGAGGACTTTAAGGGCCAAATCGTGGGACTTGGACGTGCTGGTAAGAT
GCCTAGCGGGTTTGACATTGACCCTCATCCAAAGATTCAGGCCGCGAAAAACGGTGCAGAACTAGCAGAT
GTGACTAGCGAAGTAACAGAAGAAGCGGATGGTTATACTGTGAGAGTCTATAATCCAGGTCAGGAGGGCG
ACATAGTTGAAGTTGACCTCGTCTGGAACTTAAAAAATTTACTTTTCCTTTATGATGATATCGCTGAATT
AAATTGGCAACCTCTGACAGATAGTTCAGAGTCTATTGAAAAGTTTGAATTTCATGTAAGGGGAGACAAG
GGGGCTGAAAAACTCTTTTTCCATACAGGGAAACTTTTTAGAGAGGGAACGATTGAAAAGAGTAACCTTG
ATTATACTATCCGTTTAGACAATCTTCCGGCTAAGCGTGGAGTTGAGTTGCATGCCTATTGGCCTCGGAC
CGATTTTGCTAGCGCTAGGGATCAGGGATTGAAAGGGAATCGTTTAGAAGAGTTTAATAAGATAGAAGAC
TCGATTGTTAGAGAAAAAGATCAGAGTAAACAACTCGTTACTTGGGTCCTCCCTTCGATCCTTTCCATCT
CCTTGTTATTGAGTGTCTGCTTCTATTTTATTTATAGAAGAAAGACCACTCCTTCAGTCAAATATGCCAA
AAATCATCGTCTCTATGAACCACCAATGGAATTAGAGCCTATGGTTTTATCAGAAGCAGTCTACTCGACC
TCCTTGGAGGAAGTGAGTCCCTTGGTCAAGGGAGCTGGAAAATTCACCTTTGATCAACTTATTCAAGCTA
CCTTGCTAGATGTGATAGACCGTGGGAATGTCTCTATCATTTCAGAAGGAGATGCAGTTGGTTTGAGGCT
AGTAAAAGAAGATGGTTTGTCAAGCTTTGAGAAAGACTGCCTAAATCTAGCTTTTTCAGGTAAAAAAGAA
GAAACTCTTTCCAATTTGTTTGCGGATTACAAGGTATCTGATAGTCTTTATCGTAGAGCCAAAGTTTCTG
ATGAAAAACGGATTCAAGCAAGAGGGCTTCAACTCAAATCTTCTTTTGAAGAGGTATTGAACCAGATGCA
AGAAGGAGTGAGAAAACGAGTTTCCTTCTGGGGGCTCCCAGATTATTATCGTCCTTTAACTGGTGGGGAA
AAGGCCTTGCAAGTGGGTATGGGTGCCTTGACTATCCTGCCCCTATTTATCGGATTTGGTTTGTTCTTGT
ACAGTTTAGACGTTCATGGCTATCTTTACCTCCCTTTGCCAATACTTGGTTTTCTAGGGTTAGTTTTGTC
TGTTTTCTATTATTGGAAGCTTCGACTAGATAATCGTGATGGTGTTCTAAATGAAGCGGGAGCTGAGGTC
TACTATCTCTGGACCAGTTTTGAAAATATGTTGCGTGAGATTGCACGATTGGATCAGGCTGAACTGGAAA
GTATTGTGGTCTGGAATCGCCTCTTGGTCTATGCGACCTTATTTGGCTATGCGGACAAGGTTAGTCATTT
GATGAAGGTTCATCAGATTCAAGTGGAAAATCCAGATATCAATCTCTATGTAGCTTATGGCTGGCACAGT
ACGTTTTATCATTCAACAGCACAAATGAGCCATTATGCTAGTGTCGCAAATACAGCAAGCACCTACTCTG
TATCTTCTGGAAGTGGAAGTTCTGGTGGTGGCTTCTCTGGAGGCGGAGGTGGCGGCAGTATCGGTGCCTT
TTA
Protein Sequence 
>gi|15900371|ref|NP_344975.1| hypothetical protein SP_0454 [Streptococcus pneumoniae TIGR4] MMKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEFRQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEADGYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRGDKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQGLKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVKYAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRGNVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRAKVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMGALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEAGAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQVENPDINLYVAYGWHSTFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGGSIGAF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0454 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG4907S, under S: Function unknown
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].