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SP_2101

Victor ID 3189
Gene Name SP_2101
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930243
NCBI Protein GI 15901916
Locus Tag SP_2101
Protein Accession NP_346520.1
Other Database IDs UniProtKB-ID: Q97NE2_STRPN
UniRef100: UniRef100_B2IN19
UniRef90: UniRef90_B2IN19
UniRef50: UniRef50_B2IN19
UniParc: UPI00000C9D0A
EMBL: AE005672
EMBL-CDS: AAK76160.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025226.
EnsemblGenome_TRS: EBSTRT00000025226
EnsemblGenome_PRO: EBSTRP00000024318
GenomeReviews: AE005672_GR
KEGG: spn:SP_2101
TIGR: SP_2101
HOGENOM: HBG702366
OMA: TFIFDKT
ProtClustDB: CLSK626040
BioCyc: SPNE170187-1:SP_2101-MONOMER
Taxonomy ID 170187
Gene Starting Position 2010641
Gene Ending Position 2012704
Gene Strand (Orientation) -
Protein Name cation-transporting ATPase, EI-E2 family
DNA Sequence 
>gi|194172857:2010641-2012704 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TCTATCTATTTTTAATAGACAGGCTACGCAGGACAATGCGCAAGGTTGTTAGATTATGTAAGATAGAGAG
ATTTGAAGGACTGAACCAATTAAATAAGCCAAAGCCAATCAAACTACTATTTACGACAACGGTATCCTGA
ATATTTTTCTTGATGAGTGTTTGCAAAGATGATGATAACGAATCCAACTCTTGGAAGAAATCCAAACGAT
TATCTAACAATAAGATATCACTCATCTGCTTAGAAATATCTGCACTCTCATTCATCACCACACCGATATC
TGATAGAGTTAAAGCCGCTGAGTCATTCAATCCATCTCCAACCATCAAAATAGTGTGACCTGCTTTCTGC
AGTTTCTCTACTAACTCAAATTTCCCATCAGGTTTCAAGTCTGTATAGACCTGATCAAAGGGCAAATCTT
TGACTAATTCCTCTGTCCTAATCAAGGTGTCTCCTGTTGCCAGAATCAATTTTTTCCCCTGTGCCTTAAG
TTTATCCAAGGCTGTTTTTGCTTCTTTTCTCAAAGGAGTATGAATGCAGAACATTCCAATCAATTCATTT
TGATAAGCCAAGAATAAGAGATTGTAGTGACTCTTGTACTCTTCAATTAAAGCATTTTGTTCTGAACTGA
TATGAATCTGCTCATCCTGCATCAAGACATAATTCCCAATAAGAACTGGTTGGCCATCTATATGAGATTT
GATCCCCTTGCTTGCGATATATTGGAGTTTCCCATGCATTTCCTCATGTTCAATTCCCTCTATCTCAGCT
TGCTTGACGATGGCATTAGCAATAGGATGATAAATGTGTTCCTCAAGACAGGCACTGATTCTGAGAATAT
CTTCCTCACTATAGTCTCCAAAAGGTAACACCTTTTCAACTATAGGATAACTAGTTGTGATTGTTCCTGT
CTTATCAAACAAGAAAGTATCAACTTCCAGATATTTCTCCAGAACATCTCCATCCTTAATCACCATTTCA
CGGTTCAACCCTTCCTTGATAACTGTCAAATAAGCTACAGGAGTAGAGATTTTCAAAGCGCAGGAGAAAT
CGACCAATAGGAAAGAAATAGCCTTAGAAAAAGAACCTGTCAATAGGTAAGTCAGCCCAGCCCCCAAGAA
ATTATATTTGACGACTTTATCCGCCATCTTGATGAAATAGCGTTGTTTCGTTTTCTTGTTTTCTTCAGAT
TTCTTCATCAACTCAATCAGCTGTAAAATACGGCTGTTCATCTGATTATCTGTTACACGAATGCGTAACT
CTCCAGTTTCTAATACTGTATTTGCACAAACCAAATCAGACTCTCTTTTTTCAACTGGAAAACTCTCTCC
TGTCAAGGAACTTTCGTTGACCATACCTAAACCTGAAACTACTTGTCCATCAAACAGAATTTCATTTCCT
TGAGATAAGATCAAGACATCTCCTATTTGAACATCGGAACTCTTGATACTAACAACCGTATCGCCCTGTA
CTAGGAATACATCGCTCTCTTTTGCAAGAAGACTCTGTTCTAAATCTGTTGCAGTTTTTTTCAAGGACCA
CTGATCTAAATGATTCCCCAAATCAAGCATAAACATGATATTGCTAGCTGTCTTGGATTGGTTCATAAAC
AAAGACAATAAAATAGCCGAACAGTCCAAGACTTCCATCGTTAGTTCCTTACGCGCTAGTGTTTGATAGG
CTTCTCTAATATAACCCAAAGCCTGATAACAAGTCCATATATAGCGAATAGGATACGGCACAAAACTACG
AAAAAGTACACGCTTAACCGCTGCACCTGAAACAATAGAATAAGCACTCTCTTCTCTACGAATGGGAAGA
GTCATCAACTCAGAAACTTTCCCTTTATCAATTCTTTTTAAAAAGGCTTCTGCATTATCTAATACAGAAA
AGCCTTCTTTTATGCGTAGAGTAAAGTGCTGTTGATCCATGTAAAACTGGATAGACTCAATCCCCTTTTC
ATCTCTCGCCAAGGAACGAAGATAGTCTTGAATATCCAAGGTAAGTGAAAAAGAAGATGATAGTCGGATA
TGTTGGTATCCTCTATGTAGCACTTTAAAAGACA
Protein Sequence 
>gi|15901916|ref|NP_346520.1| cation transporter E1-E2 family ATPase [Streptococcus pneumoniae TIGR4] MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQFYMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKRVLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTASNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVLILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTDNQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAISFLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTSYPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYIASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGMFCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKFELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFFQELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSLSIKNR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2101 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2217P, under P: Inorganic ion transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].