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SP_2108

Victor ID 3188
Gene Name SP_2108
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930238
NCBI Protein GI 15901923
Locus Tag SP_2108
Protein Accession NP_346527.1
Other Database IDs UniProtKB-ID: MALX_STRPN
UniRef100: UniRef100_P59213
UniRef90: UniRef90_P59214
UniRef50: UniRef50_P59214
UniParc: UPI0000051B0B
EMBL: AE005672
EMBL-CDS: AAK76167.1
RefSeq_NT: NC_003028.3
PDB: 2XD2
PDB: 2XD3
EnsemblGenome: EBSTRG00000026595
EnsemblGenome_TRS: EBSTRT00000026595
EnsemblGenome_PRO: EBSTRP00000025687
GenomeReviews: AE005672_GR
KEGG: spn:SP_2108
TIGR: SP_2108
HOGENOM: HBG727666
OMA: SADEYGF
ProtClustDB: CLSK877195
BioCyc: SPNE170187-1:SP_2108-MONOMER
Taxonomy ID 170187
Gene Starting Position 2020749
Gene Ending Position 2022020
Gene Strand (Orientation) +
Protein Name maltose/maltodextrin ABC transporter, maltose/maltodextrin-binding protein
DNA Sequence 
>gi|194172857:2020749-2022020 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGTCATCTAAATTTATGAAGAGCGCTGCGGTGCTTGGAACTGCTACACTTGCTAGCTTGCTTTTGGTA
GCTTGCGGAAGCAAAACTGCTGATAAGCCTGCTGATTCTGGTTCATCTGAAGTCAAAGAACTCACTGTAT
ATGTAGACGAGGGATATAAGAGCTATATTGAAGAGGTTGCTAAAGCTTATGAAAAAGAAGCTGGAGTAAA
AGTCACTCTTAAAACTGGTGATGCTCTAGGAGGTCTTGATAAACTTTCTCTTGACAACCAATCTGGTAAT
GTCCCTGATGTTATGATGGCTCCATACGACCGTGTAGGTAGCCTTGGTTCTGACGGACAACTTTCAGAAG
TGAAATTGAGCGATGGTGCTAAAACAGACGACACAACTAAATCTCTTGTAACAGCTGCTAATGGTAAAGT
TTACGGTGCTCCTGCCGTTATCGAGTCACTTGTTATGTACTACAACAAAGACTTGGTGAAAGATGCTCCA
AAAACATTTGCTGACTTGGAAAACCTTGCTAAAGATAGCAAATACGCATTCGCTGGTGAAGATGGTAAAA
CTACTGCCTTCCTAGCTGACTGGACAAACTTCTACTATACATATGGACTTCTTGCCGGTAACGGTGCTTA
CGTCTTTGGCCAAAACGGTAAAGACGCTAAAGACATCGGTCTTGCAAACGACGGTTCTATCGTAGGTATC
AACTACGCTAAATCTTGGTACGAAAAATGGCCTAAAGGTATGCAAGATACAGAAGGTGCTGGAAACTTAA
TCCAAACTCAATTCCAAGAAGGTAAAACAGCTGCTATCATCGACGGACCTTGGAAAGCTCAAGCCTTTAA
AGATGCTAAAGTAAACTACGGAGTTGCAACTATCCCAACTCTTCCAAATGGAAAAGAATATGCTGCATTC
GGTGGTGGTAAAGCTTGGGTCATTCCTCAAGCCGTTAAGAACCTTGAAGCTTCTCAAAAATTTGTAGACT
TCCTTGTTGCAACTGAACAACAAAAAGTATTATATGATAAGACTAACGAAATCCCAGCTAATACTGAGGC
TCGTTCATACGCTGAAGGTAAAAACGATGAGTTGACAACAGCTGTTATCAAACAGTTCAAGAACACTCAA
CCACTGCCAAACATCTCTCAAATGTCTGCAGTTTGGGATCCAGCGAAAAATATGCTCTTTGATGCTGTAA
GTGGTCAAAAAGATGCTAAAACAGCTGCTAACGATGCTGTAACATTGATCAAAGAAACAATCAAACAAAA
ATTTGGTGAATA
Protein Sequence 
>gi|15901923|ref|NP_346527.1| maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein [Streptococcus pneumoniae TIGR4] MSSKFMKSAAVLGTATLASLLLVACGSKTADKPADSGSSEVKELTVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPYDRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVKDAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKDAKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKAQAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQKVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNMLFDAVSGQKDAKTAANDAVTLIKETIKQKFGE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2108 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2182G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].