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SP_2143

Victor ID 3186
Gene Name SP_2143
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930214
NCBI Protein GI 15901956
Locus Tag SP_2143
Protein Accession NP_346560.1
Other Database IDs UniProtKB-ID: Q97NA9_STRPN
UniRef100: UniRef100_Q97NA9
UniRef90: UniRef90_Q04I29
UniRef50: UniRef50_Q04I29
UniParc: UPI0000051B37
EMBL: AE005672
EMBL-CDS: AAK76200.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026579.
EnsemblGenome_TRS: EBSTRT00000026579
EnsemblGenome_PRO: EBSTRP00000025671
GenomeReviews: AE005672_GR
KEGG: spn:SP_2143
TIGR: SP_2143
HOGENOM: HBG532911
OMA: NTAKDHR
ProtClustDB: CLSK2518149
BioCyc: SPNE170187-1:SP_2143-MONOMER
Taxonomy ID 170187
Gene Starting Position 2053397
Gene Ending Position 2056057
Gene Strand (Orientation) -
Protein Name hypothetical protein
DNA Sequence 
>gi|194172857:2053397-2056057 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATTAAATTTCTTCTTTTTTGATGAATTCTGTACGAATCTCTTGTGGAGCCAATAGTCCTGAATGAACTGG
GTATGGTCGTTCAAGTAGGTCAAGGAAGAGATGTTGACTTTCTGGCACACGTACATTTTCACTACACATA
TTGTAGTAACGAAGCACATAGCCTTCTTCATTTTCAGCTACCTTAAAGGCTGTTGGACAAACTTGCGGTA
TGCTGAGAACAGAATGGCTCAAGAGGCTACCAGTCGCAACCACGCTTCCTTCCTGTCTAGCAAGCTGAAG
GCTGGTAAACGGTGTCTGCAAGGCTTTGGCACGACGATAGGCTGAGAAGCGTTCTTGGGCTTGGTGGCAT
TCAAGTGCAAACTCGACTTCAAACTCCCGCAAGCATTGTGCTTCTGGCGTTGGGAAGTAGCCCCAGTCAC
CTAGCTCACCTGATGCACGCAAAATGGTCACGGCAATGGTGTTATCCCCAAGGATTTCGTATTCATTCAA
TCCCTTGTTGGATACAGTCACCCCTTTTTCATCGTCATACAGACTGACAAAAGCTTGTTGGTGTTGAGGA
TTTTCAGGGTTTTCCCATGAAGCAGCTGGTTTGTTTGGTCGTGTCACCACCTCATAGATACTTTCAGAAT
CATTGCTTGGACGCGTGTTATGAGTCTTGACCAAGAGACGGATACGGTGATCCTTGGCAGTGTTAGTAAA
GCGAGTCTTGAAGCGGATTTGTGGATTGTCAACGAAGACAGTCAACTCAGTTTCCAGAGGAATGTTTGTC
AATTCTTCTGACCGTCCAGCCTCACGCTTCATAAACTCGATGATACCTTGTTGCTCTTCTTCTAGCTTTT
CATCCGCACTGACAGGCACGGTCAATTCATGTTTGAGCAAGATTTTAGCATAGCAAGCTGTGTTTTCCAA
GACCTCGTGGCCCTTAAGCTCTGCAAAGATTGGCTCTGTTCCTTTTGGTTGGAAATAGATATACTCGTTT
CCGATGTCCCCACGGTCTTCAAAGCGGATAAAGTCTTCATAGGCTTCGTGAGTTGTCTTGTCATAGACTG
TGATGTTGTCATCCACACTCACCGTTACGAATGGTGTATCAATCACTCCGTTTTGGTAAATACCCTCACG
GTGTTCTTGTTTTCCTTCCAGCAATTGGAAGGTTGTCCAAGAAAGCGGCGCTAGGTGAACTGGAATGGTC
ACGCGCACTTGACGAGCAATACGAGCTTGGCGGAACTTGTCTTTTGGTAAATTATACTCAAAATTAGCTC
CGAGGTCTTCGATTGTAGCCTCTACAGGACGACCATCCAAGTCCTCCACACGGTAACTTGGCAAGATAAG
AGCAGCCATCTTTTTGTAGCCTTCTGTTGGGTGCAATTCCTTGAAATCACAAGTCGCCACATCAATCACT
GTGCTGACAGTATCGACCTTATCATGCAAGCCTGTGTTAATGACAGTAAAGAGATAGTCACTTTGAGCCT
TATCCGTAGCAATTTTACCCTTCCACTCGTTGAGCAAGTTACTTTTAACAAAGTTTCCTACTTGGTTGAC
CTTGGCAAAACGCGTTTCCATCTCGCGGTGAACTTCGTCCACGCTACAGCCACAGATACTATCATGTGGC
GCATTCTGCAAAAGTGTTTTCCAAGCATAGGTCAACTGGTCCTTGTGGTTGTGTCCACCAGTGATAATAG
TCAAGGGTTCTACCACTTGCTCTAGGAGGTTGCTATTTTCTTGGAAGGCTTGTTTTAGGTAAATGCGGGA
TGAAGAAGTGTTGGCAAGTGTGTACCAGCCATCTGTTTCCTGACTGGTCAACTCGCCTGTAACAGTTGAT
AAGTGTTCAGGAAGCGCACCTTCTACAGCTTGAACATATTCATCAAAAGAACTATGAACAAAGATTACAT
CCGGGAAGAGTTCATTTGCCACACGAATGGCTTCGCTCAGATTTTTCTGTACAGGCTGGTGGTCACAGCC
GTTCATCATCAACCATTGGTTGGTCGAAGCGTAGGCACGCACATCTGACAATTTTTGTTTCCAGAAGGTC
AAGGCCTCATCTTTGTCAACTGGAATTTCATTCCCGTTACTGTACCAGTTGGCAAAGAGAATACCTAAAA
CACGACTACCATCCACACCCTGCCAGTACATTTCTGAAAACTGAGACGTAAACTGCTCATCTTCAAGGAC
TTGGTTGTCAAATCCAATCGGCTTCACACCACGACCAAAGGCCGCCACGTGAATGCCTGATTTTTGAAGA
ATTTGAGGCGCTTGTCCCATATTTCCAAAGGTATCTGGAAAGTAGCCAATCTGGGTTGATTTACCCCATT
TGGCAGCTTCTTGTTGACCAATCAAGGTATTGCGGACATTGGCTTCACTGGAGATCAAGTAGTCATCCTG
CAAGATGTAAAAGGGACCAATTTTAAGTTTGCCCTCGTCAATGTAGCGTTGGACCTTGTCGCGATTTTCA
GGGCGAATTTGTAAGTAGTCATCAAGGACAATAGTTTGTCCATCCAAGTGGAAACTCTTGAACTCAGGGT
CATTTTCAAAGAGATCAAAGAGATTGTCAAACAATTCCACCAACTGCATACGATGGCTTTCAAAAGGCAA
GTACCACTCACGATCCCAGTGACTATGTGAGATAATATGTACAACAACATTTTCCATGAAGTAAAACCTC
A
Protein Sequence 
>gi|15901956|ref|NP_346560.1| hypothetical protein SP_2143 [Streptococcus pneumoniae TIGR4] MRFYFMENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDPEFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVRNTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQVLEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRAYASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHLSTVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQLTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATDKAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDLDGRPVEATIEDLGANFEYNLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQEHREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKGTEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSEELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVTRPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASGELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGSVVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMCSENVRVPESQHLFLDLLERPYPVHSGLLAPQEIRTEFIKKEEI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2143 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0383G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].