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SP_2145

Victor ID 3185
Gene Name SP_2145
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930213
NCBI Protein GI 15901958
Locus Tag SP_2145
Protein Accession NP_346562.1
Other Database IDs UniProtKB-ID: Q97NA7_STRPN
UniRef100: UniRef100_D9N9Y0
UniRef90: UniRef90_C1CAZ1
UniRef50: UniRef50_C1CNB9
UniParc: UPI0000051B39
EMBL: AE005672
EMBL-CDS: AAK76202.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026324.
EnsemblGenome_TRS: EBSTRT00000026324
EnsemblGenome_PRO: EBSTRP00000025416
GenomeReviews: AE005672_GR
KEGG: spn:SP_2145
TIGR: SP_2145
HOGENOM: HBG697252
OMA: HEIREMQ
ProtClustDB: CLSK876882
BioCyc: SPNE170187-1:SP_2145-MONOMER
Taxonomy ID 170187
Gene Starting Position 2057585
Gene Ending Position 2059669
Gene Strand (Orientation) +
Protein Name antigen, cell wall surface anchor family
DNA Sequence 
>gi|194172857:2057585-2059669 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGAAACCACTACTTGAAACCATCGATACCCGCTTTGGAACTACCAACAAGCATGCCTTTTCTCGGGGA
AATACCCTGCCATACACAGGCGTGCCTTTTGGGATGAATTACTTTGTGCCCCAGACCAGTGACCAGGATG
GATCTTGGTTTTTTGATCCACATCTGCCTATCTTTCAGGGGATTCGATTAACTCACCAGCCCAGTCCTTG
GATTGGGGACTACTCTTGGCTCCTTCTGACACCTGTCACCAGTCAACTGGGGGGAGACAGCCTCTTTCAC
CGCCAGTCTTCTTATGATATAGATAAAGCTTGCTTCCAGCCTCACTATTTGAAGCTCTTTTCTCTGCGTT
ATCAGATTGAAACCCAGCTCACACCGACTTGCTATGGTGCTTCTATTCGTTTGAATCAAAAGCAAGGCAA
AGCCCTCTCCCTCTATCTTCACGCAGCAGATGAACTGACAGTAGAGCAAGTAGATAAGCGGACTCTTGCC
CTGCGACAAGAAGGTAAAACTGAAACTAACAAAAATTCGCTAACGATGTTCACTGCCCTGCAAATGAACA
CGGATATTCTTGCTATCAGCCAAGAAGCTGGAGACTGGCGAATTGACTTAGCAAGTAGTCAAACCGAGAT
GCAACTAGCCACTTCTTTCATCTCTCCTTCTCAAGCTCTAATCAATCTACCTCAAGAAGATTTTGATAGC
TGTAAATCAAGTGCCCAAGTGGATTGGGAAAATCTCCTCCATCGTTTTGACATTATAGAGACAGGAGAGG
CTGACCGAACCTTCTTTGACCACTGCCTCTACAGACTCTTCCTCTTCCCACAGACTTTTTATGAGATTAA
TGAATCAGGGCAAGCCATCCACATGGATCTGGCTACTGGTACTGTCAAGCCTGGTGTCCTCTTTAGCAAC
AATGGTTTCTGGGATACCTTCCGCACCACCTTCCCCCTCTTTGCCCTTATCATACCGGAGCACTATCAAC
GCTTTTTAGAAGGTTTCCTCAATAGCTACCGCGATACTGGTTTCCTTCCAAAATGGCTGGCTCCAGATGA
ACGGGGTATGATGCCAGGTACACTTTTAGACGGTATTATCGCAGATAGCGCCTGCAAGGACATGACCCCC
GACCTAGAAGGAGAACTCTTCCAAGCCATGCTCGAAACAGCCAGCAAAGCCGACCCTCTCGGCATCAATG
GCCGCCACGGACTAGCCCAATACCAAGAACTAGGTTACCTCTCTACCGACCACCACGAAAGTGTTAGCCA
TACTCTAGACTATGCCTATAGTGACTTTTGTATCGCCAGCTGTGCCAAAAAACTAGAGAACATAGAAATC
GCTGAAACCTACAAGGCTGCTTCACAAAATTACCGCCAGCTATTTGACGCTGAGACAGGTTACATGCGAG
CACGAGACAATCAAGGAAACTTTCACCCTGACTTCTCTCCTTATAGTTGGGGGCGAGACTACGCTGAATG
CTCTGCCATTCAAGCTACTTTAGGCGTTCTCCACGACATCCCTGGCTTAATCCAACTGATGGGTGGAAAA
GAAACCTTTAGCAACTATCTTTTGAAAGCCTGTCAAGATGCTCCCCTCTTTGAAACAACAGGCTATGGTT
ACGAAATTCACGAAATGAGCGAGATGGCTACTGCTCCTTTTGGACAAATAGCCATTTCCAACCAGCCTAG
TTTCCACATTCCTTATCTCTTCCGTTACAGCGATTACCCTGACTACACTGCCCTTCTTATCAAGACGCTC
CGTCAGAAAGCTTTTCACCCAAGTTGGGAAGCCTATCCTGGAGATGAAGACAATGGTAGTCTCTCTGCTT
GGTACATCTGGTCAGCTCTCGGATTTTATCCAACCTGTCCAGGAAAACCAAGCTATGACCTCGGAATCCC
TCTCTTTGACCATCTACGAGTCTACCTCGCTAAAGAAGATAAATGGCTGGATATCCATACTAAACAAAAC
CACAACCATTTTAACTTTGTCAAAGAATGCCGACTGGACAAAACACTCGTATCAACTATTCAACACCAAG
ACCTCTTAAAAGCTGAACAACTAACTTTCACCCTCAGCTGGTTACCAAGTCACTA
Protein Sequence 
>gi|15901958|ref|NP_346562.1| cell wall antigen [Streptococcus pneumoniae TIGR4] MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSDQDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDKACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKRTLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFISPSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTFYEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADPLGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAASQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQLMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYLFRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAEQLTFTLSWLPSH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2145 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG3537G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].