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SP_2175

Victor ID 3181
Gene Name SP_2175
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930192
NCBI Protein GI 15901985
Locus Tag SP_2175
Protein Accession NP_346589.1
Other Database IDs UniProtKB-ID: Q97N83_STRPN
UniRef100: UniRef100_C1CNE8
UniRef90: UniRef90_B5E3R7
UniRef50: UniRef50_P35855
UniParc: UPI00000C9D0D
EMBL: AE005672
EMBL-CDS: AAK76229.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026966.
EnsemblGenome_TRS: EBSTRT00000026966
EnsemblGenome_PRO: EBSTRP00000026058
GenomeReviews: AE005672_GR
KEGG: spn:SP_2175
TIGR: SP_2175
HOGENOM: HBG338458
OMA: IIIELRD
ProtClustDB: CLSK876862
BioCyc: SPNE170187-1:SP_2175-MONOMER
Taxonomy ID 170187
Gene Starting Position 2091943
Gene Ending Position 2093184
Gene Strand (Orientation) -
Protein Name dltB protein
DNA Sequence 
>gi|194172857:2091943-2093184 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTATTTTTTAAACCATAGATTATTCAAGAATCCAGAAAAGATTAAGAATGACAACATGACAACATGGAA
AGTGACAACCATGCCAAGCAACTGAATCCAGCGATTCTCAGGTAGGGCAGCCTTCCCTGCTTTTTTCCGT
TCCTTATTGAGCGTTTTTTTCTTGCGAACCCAGGCATCATTGATGACCAAGCCTAGTCCATGAAAGAGTC
CATAGGCGATATAGTACCAGGTCACACCATGCCAAAATCCCATAATCAGCATATTTACAATGTAGGCCAT
GCTTGAGGTTACATTACGATTTTTAAAGACTTTCTTTCTGGTTAACACCATCACCATTCGCATAAAGACA
AAGTCACGGAACCAGAAGGACAGACTCATATGCCAGCGATTCCAAAACTCCTTTAAATCCCTTGATAAAA
AGGGCTTGTTAAAGTTGATAGGGCTACGGATTCCCATCAAGTTTGAGATGGCCAAAGCAAACATAGAATA
ACCTGCAAAGTCAAAGAAGAGTTCCAGACCAAAAGTATACATAACTGCCAAGGCATAGAGATTAAAGAAG
CCACCTGACTGCAAGGCTAAATTCTTCAGAGGAGGTAGTAAGGTCTCTCCTAAAACATGAGCTAGGATAA
ACTTATACAAAAAGCCCCACATGATATAGCGGACAGATTCATCCAGCATATCCATCAACTCATCTCGCTC
AGGAATAGCCTGATAATTTTCATTAAATCGCTTAAAGCGATCGATTGGACCACTCGAGAAAGTTGGCATG
AAGAGAAGGAAACGGAGGAATTCCCAGAGGGTAAAATCCTTAATCACTCCATCTCTCAGCTCGATGACAA
TTCCAACCGAACGAAAGGTCAGGTAAGAAATTCCCAAGAACCCAAGCAAAGACTGCGTTCCATTGATAGC
TGGTTGCACCTTGACAAAGATAATCGGAAGTAGGGACAGAAAACTAACTAAGTAGAAGACCCACTTGCCA
TCCTTGCTTTTTCGATAATGCTTGTAGAAAAGCAGGAGCAATATTTCCCAGCAAAGGTAAATACCCAAGG
CAGCTAGTTGATTGGTCTTTCCACCCACCAACATGGTGACAATAAAGAAGAGACTTACCAACACTTCATA
CCAGGCAAAGCGTTTCTTGAAAAAGAGACCTATAAAGATGGGCAAGGTTGCAGCAATCACATAAACAAAA
TACTGAGGATTGCCATATGGCTCTAAATGAGGAAGCTGTTGAAAAAACTCCA
Protein Sequence 
>gi|15901985|ref|NP_346589.1| dltB protein [Streptococcus pneumoniae TIGR4] MEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYEVLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSLLPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFMPTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLPPLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPFLSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGFWHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVTFHVVMLSFLIFSGFLNNLWFKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dltB mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1696M, under M: Cell wall/membrane/envelope biogenesis
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].