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SP_0338

Victor ID 3180
Gene Name SP_0338
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930156
NCBI Protein GI 15900269
Locus Tag SP_0338
Protein Accession NP_344873.1
Other Database IDs UniProtKB-ID: Q97SK0_STRPN
UniRef100: UniRef100_Q97SK0
UniRef90: UniRef90_B1I958
UniRef50: UniRef50_Q6GDQ0
UniParc: UPI00000513CD
EMBL: AE005672
EMBL-CDS: AAK74513.1
RefSeq_NT: NC_003028.3
HSSP: P03815
EnsemblGenome: EBSTRG00000025264.
EnsemblGenome_TRS: EBSTRT00000025264
EnsemblGenome_PRO: EBSTRP00000024356
GenomeReviews: AE005672_GR
KEGG: spn:SP_0338
TIGR: SP_0338
HOGENOM: HBG413133
OMA: RVIEQQI
ProtClustDB: CLSK877125
BioCyc: SPNE170187-1:SP_0338-MONOMER
Taxonomy ID 170187
Gene Starting Position 310722
Gene Ending Position 312827
Gene Strand (Orientation) +
Protein Name ATP-dependent Clp protease, ATP-binding subunit, putative
DNA Sequence 
>gi|194172857:310722-312827 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGA
GGATACAGTTCTGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACT
ATCGTGCGACTGGTCAATTACCAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTAT
GAAACAAGGCGGTGTCCTTGCAAAACTAGGTCGAAACTTAACAGCAGAAGCGCGTGAGGGCAAGTTGGAT
CCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGAAATCCTCTCACGCCGCACCAAGAACAATC
CTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTCTAGCGCAAGCCATTGTGAA
CGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTTGAGGCTGGT
ACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATA
TTATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAA
AGGACTTGCGGATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAA
GACGAATACCGTAACACCATCTTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATG
CTCCTTCGGCAGAGAATACTTTTAAAATTCTTCAAGGAATTCGTGACCTCTATCAACAACACCACAATGT
CATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATTCTGTTCAATACATTCCTCAACGTAGCTTG
CCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCTCAACATCCAGTAACAGATG
TGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGCAGAAGATTT
TGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAGGAAAATCGAAAACCACACAGAAGAT
ATGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGC
AAATGGAAGCTTCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCA
AGATAAGGCCGTAGAAGTTGTAGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGC
CCAATCGGCAACTTCCTCTTTGTAGGGTCTACTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCAC
TCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTAGATATGTCTGAATACAGTGACCGCACAGCTGT
TTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAGCAATACCTTAACAGAACGT
GTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGACCCTCAAGTTATTACCC
TTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACAC
TGTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCA
GAATTGATGGACCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGT
TCTCACACTTGACTAAGGAAGACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTT
GGCTAAGAAAGACATTGACTTGGTAGTCAGTCAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGAC
GAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACAAGAAATTCGTGATAAGGTGACAGACTTCC
ACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCGTTTTGGTTATTCGTGAGAA
AGTCTA
Protein Sequence 
>gi|15900269|ref|NP_344873.1| ATP-dependent Clp protease ATP-binding subunit [Streptococcus pneumoniae TIGR4] MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQGGVLAKLGRNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTGIPVSQMEASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0338 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0542O, under O: Posttranslational modification, protein turnover, chaperones
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].