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SP_0320

Victor ID 3178
Gene Name SP_0320
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930133
NCBI Protein GI 15900252
Locus Tag SP_0320
Protein Accession NP_344856.1
Other Database IDs UniProtKB-ID: Q97SL2_STRPN
UniRef100: UniRef100_Q97SL2
UniRef90: UniRef90_E0SVG6
UniRef50: UniRef50_C5BK69
UniParc: UPI00000513B9
EMBL: AE005672
EMBL-CDS: AAK74496.1
RefSeq_NT: NC_003028.3
HSSP: P29132
EnsemblGenome: EBSTRG00000026845.
EnsemblGenome_TRS: EBSTRT00000026845
EnsemblGenome_PRO: EBSTRP00000025937
GenomeReviews: AE005672_GR
KEGG: spn:SP_0320
TIGR: SP_0320
HOGENOM: HBG750976
OMA: CDVTDEV
ProtClustDB: PRK07097
BioCyc: SPNE170187-1:SP_0320-MONOMER
Taxonomy ID 170187
Gene Starting Position 294161
Gene Ending Position 294976
Gene Strand (Orientation) -
Protein Name gluconate 5-dehydrogenase
DNA Sequence 
>gi|194172857:294161-294976 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTACTCAGGTTGTTTTCCGATGTAGGCTAAGATACCGCCATCTACATATAGGATGTGGCCATTGACAAA
ATTGCTGGCATCACTAGCGAGAAAGACAGCAGGGCCCATCAAATCTTCAGTATTTCCCCAACGTGCAGCA
GGTGTTTTTGCAATGATGAACTGGTCAAATGGGTGGCGAGAACCATCTTCTTGCAATTCACGAAGAGGTG
CTGTTTGAGGAGTGGCAATATAACCCGGTCCAATTCCGTTACATTGGATATTGGCTCCACCGTATTCAGA
CGCAATGTTGCGGGTCAACATTTTCAAGCCCCCTTTAGCAGCAGCATAAGCGCTAACTGTTTCACGTCCC
AGTTCGCTCATCATCGAACAAATATTGATAATCTTTCCATGCCCTTTCTTTATCATAGAAGGAATAACTG
CCTTTGAAACGATAAATGGTGCGTTTAAGTCAATATCGATGACCTTACGGAAATCAGCGGCGCTCATTTC
GCACATTGGAACTCGGCGGATAATACCAGCGTTATTAACGAGGATGTCAATGACACCAACCTCTTGTTCG
ATTTGCTTGACCATGGCTTGGATACCGTCCTCGTCTGTCACGTCACAGACATATCCATGGGCTTGGATGC
CAACTTCACGATAAGCTTCAATCCCTTTATTGACCAGATCTTGATTGATATCGTTAAAGACAATAGTAGC
GCCGGCTTCAGCGTAGGATTTGGCAATAGCAAATCCAATTCCATAAGAAGCGCCGGTGATGAGAGCAATT
TTTCCTTTTAAAGAAAACTGCTCAATTGAGAATGATGTATTTGTCA
Protein Sequence 
>gi|15900252|ref|NP_344856.1| gluconate 5-dehydrogenase [Streptococcus pneumoniae TIGR4] MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVFNDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGIIRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRETVSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFDQFIIAKTPAARWGNTEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0320 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1028IQR, under I: Lipid transport and metabolism; Q: Secondary metabolites biosynthesis, transport and catabolism; R: General function prediction only
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].