Victors

SP_0314
Victor ID	3177
Gene Name	SP_0314
Sequence Strain (Species/Organism)	Streptococcus pneumoniae TIGR4
NCBI Gene ID	930127
NCBI Protein GI	15900247
Locus Tag	SP_0314
Protein Accession	NP_344851.1
Other Database IDs	UniProtKB-ID: HYSA_STRPN UniRef100: UniRef100_Q54873 UniRef90: UniRef90_Q54873 UniRef50: UniRef50_Q54873 UniParc: UPI000012D052 EMBL: AE005672 EMBL: L20670 EMBL-CDS: AAK74491.1 EMBL-CDS: AAA53685.1 EMBL-CDS: AAA53686.1 RefSeq_NT: NC_003028.3 PDB: 1C82 PDB: 1EGU PDB: 1F9G PDB: 1LOH PDB: 1LXK PDB: 1N7N PDB: 1N7O PDB: 1N7P PDB: 1N7Q PDB: 1N7R PDB: 1OJM PDB: 1OJN PDB: 1OJO PDB: 1OJP PDB: 1W3Y PDB: 2BRP PDB: 2BRV PDB: 2BRW EnsemblGenome: EBSTRG00000025915 EnsemblGenome_TRS: EBSTRT00000025915 EnsemblG
Taxonomy ID	170187
Gene Starting Position	287482
Gene Ending Position	290682
Gene Strand (Orientation)	+
Protein Name	hyaluronidase
DNA Sequence	>gi\|194172857:287482-290682 Streptococcus pneumoniae TIGR4 chromosome, complete genome CATGCAAACAAAAACAAAGAAGCTCATTGTGAGTTTGTCTTCACTTGTTTTATCAGGATTTTTATTAAAC CATTATATGACAATTGGAGCGGAAGAAACGACTACGAATACCATTCAGCAAAGCCAGAAGGAAGTTCAGT ATCAGCAAAGGGATACAAAAAATTTAGTTGAAAATGGTGATTTTGGTCAGACGGAGGACGGAAGCAGTCC GTGGACAGGAAGCAAAGCTCAGGGGTGGTCAGCTTGGGTAGACCAGAAGAATAGTGCAGATGCCTCAACT CGAGTCATTGAGGCTAAGGATGGGGCTATCACTATCTCAAGCCATGAGAAATTAAGGGCAGCGCTTCACC GTATGGTTCCTATTGAAGCTAAGAAAAAGTATAAACTGCGTTTCAAGATTAAAACAGATAATAAAATCGG GATTGCCAAAGTTCGTATCATTGAGGAAAGTGGTAAGGACAAGCGATTGTGGAATTCTGCAACGACGTCA GGAACAAAGGACTGGCAGACCATTGAAGCAGACTATAGCCCGACTTTAGATGTTGATAAAATCAAGCTGG AGTTATTCTATGAAACAGGAACTGGGACTGTTTCCTTTAAGGATATTGAGCTGGTAGAGGTAGCAGACCA GCTTTCTGAGGATTCTCAAACAGATAAACAGCTTGAGGAAAAGATTGATTTACCAATTGGAAAAAAACAT GTTTTTTCTCTTGCGGACTATACTTATAAGGTAGAAAATCCTGACGTTGCTTCAGTCAAAAATGGAATTT TAGAACCTCTTAAGGAAGGGACAACCAATGTCATTGTCAGTAAAGATGGCAAGGAAGTGAAAAAGATTCC TTTGAAGATTCTGGCCTCTGTTAAGGATGCATACACAGACCGTTTGGATGACTGGAATGGCATCATCGCT GGGAATCAATACTATGATTCTAAAAATGAACAGATGGCCAAATTAAACCAGGAATTGGAAGGAAAGGTAG CTGATAGCCTATCCAGTATTTCAAGTCAGGCGGACCGCACCTATTTGTGGGAAAAATTTTCAAATTATAA AACGTCTGCAAATCTGACTGCCACTTATCGGAAATTGGAGGAGATGGCCAAGCAAGTGACCAATCCTTCT TCTCGTTATTATCAAGATGAAACTGTCGTTCGAACAGTCAGGGATTCCATGGAATGGATGCATAAACATG TCTACAATAGTGAAAAGAGCATTGTTGGGAACTGGTGGGATTATGAAATCGGTACACCTCGTGCCATCAA CAATACCTTGTCTCTGATGAAAGAATACTTCTCTGATGAGGAAATTAAAAAATATACAGATGTGATTGAA AAATTTGTACCAGATCCCGAACATTTCCGAAAGACGACTGATAACCCATTCAAGGCTCTAGGTGGAAACT TAGTTGATATGGGAAGGGTAAAAGTAATAGCTGGTTTACTGCGTAAGGATGATCAAGAAATTTCTTCTAC CATTCGCTCGATTGAGCAAGTGTTCAAGTTGGTAGACCAAGGTGAAGGTTTTTATCAAGATGGATCCTAT ATCGACCACACCAATGTTGCCTATACGGGTGCTTATGGGAATGTTTTGATTGATGGCCTGTCTCAACTGT TGCCAGTCATTCAAAAGACCAAGAATCCAATCGATAAAGATAAAATGCAAACCATGTACCACTGGATTGA TAAATCGTTTGCTCCTTTGCTGGTGAATGGAGAGTTGATGGATATGAGTCGTGGACGCTCGATCAGTCGT GCAAATAGCGAGGGGCACGTGGCCGCAGTAGAAGTACTAAGAGGGATTCACCGAATAGCGGATATGTCTG AAGGAGAAACCAAACAATGTTTGCAGAGTCTTGTGAAGACCATTGTTCAATCGGATAGTTATTATGATGT CTTTAAGAATTTGAAGACTTATAAGGATATCAGTTTGATGCAATCCTTGTTAAGTGATGCAGGAGTCGCA AGTGTTCCAAGACCAAGTTACCTATCTGCCTTTAACAAGATGGATAAAACAGCCATGTACAATGCAGAGA AAGGGTTTGGATTTGGCTTGTCACTCTTTTCCAGTCGTACCTTGAATTACGAACACATGAACAAGGAAAA TAAACGTGGTTGGTATACGAGTGATGGGATGTTCTATCTTTACAATGGCGATTTGAGTCACTATAGCGAT GGCTACTGGCCAACAGTTAATCCATATAAGATGCCTGGTACAACAGAGACGGATGCTAAGAGAGCGGATA GCGATACAGGTAAAGTTTTACCGTCTGCTTTCGTTGGAACGAGCAAACTAGATGATGCCAATGCGACAGC AACCATGGATTTCACCAACTGGAATCAAACATTGACTGCTCATAAGAGCTGGTTTATGCTAAAGGATAAG ATCGCCTTTTTAGGAAGCAATATCCAAAACACTTCAACAGATACTGCTGCAACTACAATTGACCAGAGAA AACTGGAATCAGGTAATCCATATAAAGTCTATGTCAATGATAAAGAAGCCTCCCTTACAGAACAAGAAAA GGATTATCCTGAAACCCAAAGTGTCTTTTTAGAATCGTTCGATTCGAAAAAGAATATTGGTTACTTTTTC TTTAAGAAGAGTTCAATCAGTATGAGTAAGGCTTTGCAAAAGGGAGCCTGGAAGGATATCAATGAAGGAC AGTCAGACAAGGAAGTTGAAAATGAATTTCTTACGATTAGTCAGGCTCATAAGCAAAATAGAGATTCTTA TGGCTATATGCTCATTCCTAACGTGGATCGTGCCACCTTCAATCAAATGATAAAAGAGTTAGAAAGTAGC CTCATCGAAAATAACGAAACCCTTCAGTCTGTTTATGATGCTAAACAAGGAGTTTGGGGCATTGTGAAAT ATGATGATTCTGTCTCTACTATTTCCAACCAATTCCAAGTTTTGAAACGTGGAGTCTATACCATTCGAAA AGAAGGGGATGAATATAAGATTGCCTACTATAATCCTGAAACCCAGGAATCAGCTCCAGATCAGGAAGTC TTTAAAAAGCTAGAGCAAGCAGCTCAGCCACAAGTACAGAATTCAAAAGAAAAGGAAAAATCTGAAGAGG AAAAGAACCATTCGGATCAAAAGAATCTCCCTCAGACAGGAGAAGGTCAGTCAATCTTGGCAAGTCTAGG GTTCTTGCTACTTGGGGCATTTTATCTATTCCGTAGAGGAAAGAACAACTA
Protein Sequence	>gi\|15900247\|ref\|NP_344851.1\| hyaluronidase [Streptococcus pneumoniae TIGR4] MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKEVQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGAITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTDKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEVKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSISSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQCLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESGNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNRDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNHSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: SP_0314 mutant is attenuated in mice (Hava and Camilli, 2002).
References	Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].


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SP_0314