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SP_0306

Victor ID 3175
Gene Name SP_0306
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930119
NCBI Protein GI 15900239
Locus Tag SP_0306
Protein Accession NP_344843.1
Other Database IDs UniProtKB-ID: Q97SM4_STRPN
UniRef100: UniRef100_Q97SM4
UniRef90: UniRef90_A5LJM8
UniRef50: UniRef50_B2ISN0
UniParc: UPI00000513AC
EMBL: AE005672
EMBL-CDS: AAK74483.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026516.
EnsemblGenome_TRS: EBSTRT00000026516
EnsemblGenome_PRO: EBSTRP00000025608
GenomeReviews: AE005672_GR
KEGG: spn:SP_0306
TIGR: SP_0306
HOGENOM: HBG697210
OMA: NEDETAY
ProtClustDB: CLSK803695
BioCyc: SPNE170187-1:SP_0306-MONOMER
Taxonomy ID 170187
Gene Starting Position 279126
Gene Ending Position 280607
Gene Strand (Orientation) +
Protein Name transcriptional regulator, putative
DNA Sequence 
>gi|194172857:279126-280607 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGAATGTGTTAAACATTAAAGAGAAAGATATCCTTCAATTTTTAATAAAAAATAAGGAACGTTTTGTT
ACAAGCAAAGAACTGGCAGAATATTTATCCTGTTCAGATAGAACTGTCCGTAATGTACTGAAATTAATTG
AGAAGACAATGATTATTCAAGGAGTCCGGTTGATTTCAAAACAAGGTCAAGGGTATCAAATATTTTTTGA
GAATCAAGGCGCTTACCAGGAGTTTAGACAAACTTATGAACTGGAAGAAGACTATACGAAAACTGCGGTT
TCAAAAGGTGATGATCGTTTAGTATTTATCTTAAATAAATTATTATTTGAGCAAGTTCCAGTTCTTTTTG
ATGATTTAGCTGATGAACTTTACGTTAGTCGTTCAACATTATCTCATGATTTCAGAAAGATACGAGTGAT
GTTATCAGAGTATAATTTGTCCATTGAGAGTAGGGCGAATAAAGGAGTTTATGTCTCAGGCGAGGAACGT
GATAAACGACGTTTTATCATAAATTATTTCCTAGAGAATCAATTTTTTAAAACAATACATTGCTATGTAA
AATTTAACTTTTTTGATCAAACTGTTCCATTAGAAGAATTTGCTAGAATTGTTTTGGATGAATGCCAAGA
GGCCAACCTAAAACTATCTGATTTTGTACTACAGAATTTAGTAGTTCACATAGCATTGTCTGTGATTCGT
TTAAAATCCGGATTTGAAATAAAAAATATAGACTGTCAGATGACTGATGATGCAATAGAGAGAAAGGTTG
CCCAAAGAATTCTTTCTAAAGTAAGAGAAGTAACAAATCAGGAATTTCCAGTTCAGGAAATAGACTACAT
TACTTTGCATTTGTTAGCTAAGAGTCAACAATGTCAAAAAAATCAGAAGAATATTTCTGAAGAAGTTTTA
AAAAAATCTTTATTTAAAACATTTCAGAATTTAGGATTAGATGATATGTATAACTTTTCTTCAGATTTCC
AACTAATTGAAGGATTGATAACTCATCTAATGACACTACAAGTACGTTTAGAAAGCCGGATTACCTTAAA
TAACCCTTTGGTAGATGAAATTAAACAGAATTATAGTGATATATTCTTTATGACTAGAGAAATTCTTGCA
AATATGGACAAGTTCTTGGAGTGGACAATATCAGATGATGAAGTAGCATATGTAAGTCTTCACTTTTTAG
CTGCTATGGAACGTAGCAAAGAGAGTACTAAGTTTAATATTCTTGCTATTTGTGCAACAGGATTTGGTGC
AGCCCAAATGTTAAGAAATCGTTTGGAAACGGAGTTTGGGAAGCGAGTAGAAGTTGTTGATGTAATAGGC
TACTATGAATTGAATCAAGAAAAACTTAAAGGAATAGATTTTATAGTGTCAGCTATTGATTTATCAAATC
TATATTTTCAAATCCCAGTTTTTAAAGTTAGTGTGTTTCTTAAGAGTGATGAGATGGAAATGATTAGAAA
AGCTATGGATTA
Protein Sequence 
>gi|15900239|ref|NP_344843.1| transcriptional regulator [Streptococcus pneumoniae TIGR4] MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLKLIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVFILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSGEERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDFVLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQEIDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLITHLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVSLHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQEKLKGIDFIVSAIDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0306 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG3711K, under K: Transcription
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].