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SP_0265

Victor ID 3170
Gene Name SP_0265
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930071
NCBI Protein GI 15900199
Locus Tag SP_0265
Protein Accession NP_344803.1
Other Database IDs UniProtKB-ID: Q97SR0_STRPN
UniRef100: UniRef100_C1CB40
UniRef90: UniRef90_D6ZQC0
UniRef50: UniRef50_O05508
UniParc: UPI0000051382
EMBL: AE005672
EMBL-CDS: AAK74443.1
RefSeq_NT: NC_003028.3
HSSP: P11546
EnsemblGenome: EBSTRG00000025354.
EnsemblGenome_TRS: EBSTRT00000025354
EnsemblGenome_PRO: EBSTRP00000024446
GenomeReviews: AE005672_GR
KEGG: spn:SP_0265
TIGR: SP_0265
HOGENOM: HBG316462
OMA: HYPNEVD
ProtClustDB: CLSK877196
BioCyc: SPNE170187-1:SP_0265-MONOMER
Taxonomy ID 170187
Gene Starting Position 238197
Gene Ending Position 239576
Gene Strand (Orientation) +
Protein Name glycosyl hydrolase, family 1
DNA Sequence 
>gi|194172857:238197-239576 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGCTAAGATTTCCAAAGGATTTTGTCTGGGGATCCTCTACTTCTGGACCGCAGACAGAAGGACGTGTA
GCTGGTGACGGTAAGGGAGACAATCTCTGGGATTACTGGTTCCAAGTGGAGCCAAATCGTTACTATAATG
GGATTGGTTCAGATAAGACATCGACTTTTTATGAAAATTGGGAGCGGGATATTGAGCTTTTGTTAGAGAC
TGGTCACACAGCCTTTCGGACTTCTATTCAGTGGTCACGGATTTTTCCACAAGGCTGTGGAAAAGTCAAC
ACTCAAGGTGTGGATTTTTATCGTAAGGTCTTTGAGGCTATTAAGGCTAAAGGAATTCGTCTGTTAGTCA
ATCTCTATCATTTTGATTTACCTTTTGCCCTTCAAGAGGATGGTGATGGTTGGGAAAATAAGGCGACAGT
CTCAGCCTATGAAGACTATGCTCGTTTTTGTTTTGAGACTTATGGAGATTTAGTGGATCAATGGATTACC
TTTAACGAGCCCATCGTTCCTGTAGAATTTGGTTATTTTTATGATGCCCATTATCCACATAAGGTGGATG
CAGAGGCAGCTGTTAAGGTAGCCTATCATACACAATTGGCCAGCAGCCGGGCTGTTAAGGCTTGCCATGA
ACTTTTGCCTGATTCCAAGATTGGGATTGTCCTCAACTTGACACCGGCTTATCCACGTAGCCAGCATCCT
GCTGATGTCAAGGCAGCTCGTATTGCGGCCCTTTTTCAGGCCCAATCTTTCTTAGATCCATCTGTCTTGG
GGACTTATCCACAGGAGTTGGTAGAAATCTTGCATGAACACGGTCTTTTACCTGATGCTACAGAGGAAGA
GTTGGAACTCATTCGTGATAATACGGTGGACTTCCTTGGTGTGAACTACTATCAACCTTTGCGTGTTATG
GCTCCTCGATTTGCTAAGCATCCAGAGAGTCCACTCTTACCAGAACATTTTTACGAGCCTTATGTGATGC
CTGGACGTAAAATCAATTCTCACCGTGGTTGGGAGATTTATGAGCAAGGGATTTATGACATCGCCCAAAA
TATCAAGGAAAATTATGGCAATATTGAGTGGATGTTGACTGAGAATGGTATGGGTGTTGAAGGGGAAGAA
AAATTCCGTCAAGATGGAATGATTCAAGATGATTACCGTATTGACTTTGTAAAAGGTCATCTTCGTGAAC
TTCACCGTGCCATTGAAGATGGTGCCAACTGTAAGGGCTACTTGATTTGGACCTTTATTGACTGCTGGTC
ATGGCTCAACAGCTATAAAAATCGCTATGGTTTGGTCGAATTAGACTTGGAAACGCAAGAACGTCGTCTG
AAGAAATCAGGCCACTGGTTCAAAGAATTAAGCGATAATAATGGATTTTA
Protein Sequence 
>gi|15900199|ref|NP_344803.1| glycosyl hydrolase [Streptococcus pneumoniae TIGR4] MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRYYNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRKVFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQWITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIGIVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDATEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSHRGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKGHLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWFKELSDNNGF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0625 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2723G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].