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SP_0251

Victor ID 3167
Gene Name SP_0251
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930053
NCBI Protein GI 15900186
Locus Tag SP_0251
Protein Accession NP_344790.1
Other Database IDs UniProtKB-ID: Q97SS3_STRPN
UniRef100: UniRef100_Q97SS3
UniRef90: UniRef90_B2ISH7
UniRef50: UniRef50_C6SS13
UniParc: UPI0000051372
EMBL: AE005672
EMBL-CDS: AAK74430.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026388.
EnsemblGenome_TRS: EBSTRT00000026388
EnsemblGenome_PRO: EBSTRP00000025480
GenomeReviews: AE005672_GR
KEGG: spn:SP_0251
TIGR: SP_0251
HOGENOM: HBG457670
OMA: ARICDKV
ProtClustDB: CLSK877309
BioCyc: SPNE170187-1:SP_0251-MONOMER
Taxonomy ID 170187
Gene Starting Position 220065
Gene Ending Position 222503
Gene Strand (Orientation) +
Protein Name formate acetyltransferase, putative
DNA Sequence 
>gi|194172857:220065-222503 Streptococcus pneumoniae TIGR4 chromosome, complete genome
GATGGTAAATACAGAAGTAGCAAGAACAACAATCAAGACAGAATATTTTGGCAGCCTTACTGAAAGGATG
AACAAATATCGAGAAGATGTTTTAAATAAAAAACCTTATATTGATGCTGAGAGAGCAGTTCTAGCAACAC
GCGCCTATGAACGATACAAGGAACAACCTAATGTCCTAAAACGTGCATATATGCTGAAAGAAATTTTGGA
AAATATGACTATCTATATTGAAGAAGAATCTATGATTGCGGGAAATCAAGCTTCTTCCAATAAAGATGCT
CCTATTTTTCCGGAATATACGCTAGAATTTGTTCTCAATGAGTTGGATCTTTTTGAAAAGCGTGATGGAG
ATGTTTTCTATATTACAGAAGAAACAAAAGAACAACTTAGAAGTATTGCTCCGTTTTGGGAAAATAATAA
TTTACGTGCTAGAGCTGGTGCCTTATTACCTGAAGAAGTGTCTGTTTATATGGAAACAGGATTCTTCGGT
ATGGAAGGTAAGATGAATTCTGGAGATGCTCACTTAGCAGTTAACTATCAGAAACTTTTGCAATTTGGTT
TAAGAGGTTTTGAAGAGCGGGCTCGTAAAGCAAAAGTAGCTCTAGATTTAACAGATCCAGCAAGTATTGA
TAAATATCATTTTTACGACTCTATATTTATCGTAATCGATGCTATTAAAGTATATGCAAAGCGCTTTGTT
GCTCTTGCTAAAAGTTTAGCCGAAAATGCAAATCCTAAACGTAAGAAAGAATTACTTGAGATTGCAGATA
TTTGCTCTAGAGTCCCATATGAACCGGCAACTACTTTTGCAGAAGCTATTCAATCAGTTTGGTTTATTCA
ATGTATTTTACAAATTGAATCTAATGGCCACTCTCTTTCATATGGCCGTTTTGATCAATATATGTATCCA
TATATGAAGGCTGATTTAGAAAGTGGTAAAGAAACAGAAGATAGCATTGTTGAACGTCTGACAAATCTTT
GGATTAAGACAATTACAATTAATAAGGTTCGCAGTCAATCACATACATTTTCTTCAGCAGGAAGTCCTTT
ATATCAAAATGTTACAATTGGTGGACAGACTCGAGATAAGAAGGATGCTGTTAACCCATTATCTTATTTG
GTATTAAAATCAGTTGCACAAACCCATCTACCGCAACCTAATCTAACTGTACGTTACCATGCAGGTTTAG
ATGCTCGTTTCATGAATGAGTGTATTGAAGTGATGAAACTTGGTTTTGGTATGCCTGCATTTAATAATGA
TGAGATTATTATTCCTTCTTTTATTGCAAAAGGAGTATTGGAAGATGATGCTTATGATTACAGTGCCATT
GGATGTGTTGAAACGGCAGTTCCAGGGAAATGGGGCTATCGTTGCACAGGTATGAGTTATATGAACTTCC
CTAAGGTTCTACTTATCACGATGAATGATGGAATTGATCCGGCTTCGGGTAAACGGTTTGCACCAAGCTT
TGGTCGTTTTAAGGATATGAAGAACTTTTCTGAATTAGAAAATGCTTGGGATAAAACACTAAGATATTTG
ACACGAATGAGTGTTATTGTTGAAAATTCTATTGATTTATCATTGGAACGAGAAGTTCCTGATATTCTAT
GTTCAGCATTGACTGATGATTGTATTGGTCGTGGAAAACACCTTAAAGAAGGTGGAGCAGTATATGATTA
TATATCAGGATTGCAAGTTGGAATTGCAAATTTGTCGGATTCATTAGCTGCAATTAAAAAATTGGTGTTT
GAGGAAGAACGTATAAGCCCAAGTCAGCTTTGGCATGCACTGGAAACAGATTATGCCGGAGAAGAAGGTA
AGGTCATTCAAGAAATGTTGATTCATGATGCACCTAAGTATGGTAATGATGATGATTATGCTGACAAATT
GGTTACTGCTGCTTATGACATTTATGTTGATGAAATTGCTAAATATCCTAATACACGTTATGGAAGAGGG
CCTATTGGAGGAATTCGTTATTCAGGAACATCTTCTATCTCAGCCAACGTAGGGCAGGGACGTGGAACAT
TAGCAACTCCAGATGGACGCAACGCGGGTACACCGTTAGCAGAGGGTTGTTCACCATCACATAATATGGA
TCAACACGGCCCTACATCTGTTTTAAAATCTGTTTCAAAATTACCAACAGATGAAATCGTAGGTGGGGTT
CTCTTAAATCAGAAAGTAAATCCTCAAACGTTAGCCAAAGAAGAAGATAAATTAAAACTAATTGCTTTGT
TACGAACATTCTTTAATCGTTTACATGGGTACCATATTCAATACAATGTTGTTTCCAGAGAGACGCTGAT
TGACGCTCAGAAACATCCTGAAAAACACAGAGACTTAATTGTTCGTGTTGCAGGATACTCTGCATTCTTC
AATGTTCTTTCTAAGGCAACCCAAGATGACATTATAGGACGTACTGAGCATACTTTGTA
Protein Sequence 
>gi|15900186|ref|NP_344790.1| formate acetyltransferase [Streptococcus pneumoniae TIGR4] MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVLATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETGFFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSIFIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSVWFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGRFKDMKNFSELENAWDKTLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQVGIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDDDYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDGRNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDIIGRTEHTL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0251 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1882C, under C: Energy production and conversion
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].