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SP_0246

Victor ID 3165
Gene Name SP_0246
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 930048
NCBI Protein GI 15900181
Locus Tag SP_0246
Protein Accession NP_344785.1
Other Database IDs UniProtKB-ID: Q97SS8_STRPN
UniRef100: UniRef100_B2ISH2
UniRef90: UniRef90_B2ISH2
UniRef50: UniRef50_B2ISH2
UniParc: UPI000005136D
EMBL: AE005672
EMBL-CDS: AAK74425.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025790.
EnsemblGenome_TRS: EBSTRT00000025790
EnsemblGenome_PRO: EBSTRP00000024882
GenomeReviews: AE005672_GR
KEGG: spn:SP_0246
TIGR: SP_0246
HOGENOM: HBG694151
OMA: EVVQYMS
ProtClustDB: CLSK877313
BioCyc: SPNE170187-1:SP_0246-MONOMER
Taxonomy ID 170187
Gene Starting Position 215991
Gene Ending Position 216737
Gene Strand (Orientation) +
Protein Name transcriptional regulator, DeoR family
DNA Sequence 
>gi|194172857:215991-216737 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGAAAAGATTGGAACAAATTATTAAATTAGTATCAGAATATGAAAAGATCGACGTTAATACATTATCG
GAAAAATTAAATGTATCGAAAGTAACGATTAGAAAAGATTTAGATAAATTAGAGTCAAAAGGTTTATTAC
ACAGAGAGCATGGATATGCTGTATTAAATAGTGGAGATGACTTAAATGTACGTTTGTCAATTAATTATGA
AACTAAGAGAAAAATTGTTCAGGAAGCAGTAAAATTGGTGTCAGATAATGAAACAATAATGATAGAATCT
GGATCGACCTGTGCTTTACTTGCTGAGGAAATTTGCAAGCAAAAAAGAAATGTTACGATTGTAACAAATT
CGTTTTTTATAGCAAATTTTGTGAGAGCTTATGATTCATGTCGTGTTATTGTTCTTGGTGGTGAGTTTCA
GAAAGATTCACAGGTGACTGTAGGACCTTTATTAAAAGAAATGATACAGACTTTTCATGTGTGTCAAGCT
TTTGTTGGGACAGATGGTTACGATAAAGAGATGGGCTTTACCGGAAAAGATTTAATGCGCAGTGAGGTAG
TTCAATATATTTCAGCAGTGTCGGATAAAGTCATTGTCCTAACTGACTCAAGTAAATTTGATAAAAGAGG
TACAGTAAGAAGATTTGCTTTAAGTCAAGTCTATGAAGTAATAACAGACGAAAAACTTTCTAAACAAAAT
ATAGCTACATTAGAAAATGCTGGGATAATGGTTAAGGTAGTTTCGTA
Protein Sequence 
>gi|15900181|ref|NP_344785.1| DeoR family transcriptional regulator [Streptococcus pneumoniae TIGR4] MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKGLLHREHGYAVLNSGDDLNVRLSINYETKRKIVQEAVKLVSDNETIMIESGSTCALLAEEICKQKRNVTIVTNSFFIANFVRAYDSCRVIVLGGEFQKDSQVTVGPLLKEMIQTFHVCQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAVSDKVIVLTDSSKFDKRGTVRRFALSQVYEVITDEKLSKQNIATLENAGIMVKVVS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0246 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1349KG, under K: Transcription; G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].