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SP_1964

Victor ID 3159
Gene Name SP_1964
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 929957
NCBI Protein GI 15901787
Locus Tag SP_1964
Protein Accession NP_346391.1
Other Database IDs UniProtKB-ID: NUCE_STRPN
UniRef100: UniRef100_P0A3S4
UniRef90: UniRef90_P0A3S4
UniRef50: UniRef50_P0A3S4
UniParc: UPI0000051A73
EMBL: X54225
EMBL: AE005672
EMBL-CDS: CAA38134.1
EMBL-CDS: AAK76031.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000027225
EnsemblGenome_TRS: EBSTRT00000027225
EnsemblGenome_PRO: EBSTRP00000026317
GenomeReviews: AE005672_GR
KEGG: spn:SP_1964
TIGR: SP_1964
HOGENOM: HBG698106
OMA: NYYETKI
ProtClustDB: CLSK884177
BioCyc: SPNE170187-1:SP_1964-MONOMER
Taxonomy ID 170187
Gene Starting Position 1872209
Gene Ending Position 1873033
Gene Strand (Orientation) -
Protein Name DNA-entry nuclease
DNA Sequence 
>gi|194172857:1872209-1873033 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTACTGAGTTACAGTTACTTCTCCAGTTCGGTAATCCAGTTGAAGTCCCTTTTGAACATTGGGAACTAG
AACATTGAATTCCAATTCTCCATCCGAAGACTTGGCTTCAATCTGTGAAGCTGAGGGAACTAAATCCTCG
TTTGAAGCGTAGTAAAGGGTTACACGGTAACGGACACGCTTGTTTTGGTCCAAGGCTTTACGCACCTTGC
TTTCATAGTAGTTTTGACCAGTCGAATACTCGGCTTGTGCCTGATTTGCCCAGGCTGTCTGAACAGCAAT
GTTTTTAGGATTGCTTGTTGAGGCATCAAAACCATCCAAACCACCGATTAAGGCATAGCCTAACAAATGA
CCTCTATCGACTGCATGGGTATAAGAGCCCTTTAGATTCTTGACCTGATGCCAACCTGGAGGAGTCCAAG
AAGTTGAACCATTCCCAGTTTCTTTACGATTCTTGTACTGACGAGTGGCCTTAGACAAGAGGGCATTAGC
TACGGTTGGAACAGTTTCCTTGCCCACTGTCTTTGTTTTATTGTCAGCGTAGGGCTTACTTGAAACCTTG
GCATCTAGATTTGTTTTATTACCATTGACGATAAAAGCACCTGAGCCATTCCACTCCAGACTCCCCTTTA
TTTGACTCTTGACTGCGTCTGTTAAGACACTCTCTGCCAATGCTTGACTAGGAGCTTCAGACGCTTGTTT
TTTCTGACTAAGATTGGTTTTGGGACTATTAGGTGCCGACGGCATCTGCTTGATATAATAGCTCCCTGTA
GACAAAAGCAATAACACTAGCAGTCCGATTAGTGTCTGTCTTGTTTTTTTGTTCA
Protein Sequence 
>gi|15901787|ref|NP_346391.1| DNA-entry nuclease [Streptococcus pneumoniae TIGR4] MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGHLLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1964 mutant is attenuated in mice (Hava and Camilli, 2002).
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].