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SP_0156

Victor ID 3156
Gene Name SP_0156
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 929947
NCBI Protein GI 15900094
Locus Tag SP_0156
Protein Accession NP_344698.1
Other Database IDs UniProtKB-ID: Q9RIP5_STRPN
UniRef100: UniRef100_Q9RIP5
UniRef90: UniRef90_B1I8E3
UniRef50: UniRef50_C1CP35
UniParc: UPI000005130D
EMBL: AE005672
EMBL: AJ006396
EMBL-CDS: AAK74338.1
EMBL-CDS: CAB54577.1
RefSeq_NT: NC_003028.3
HSSP: Q56312
EnsemblGenome: EBSTRG00000027098.
EnsemblGenome_TRS: EBSTRT00000027098
EnsemblGenome_PRO: EBSTRP00000026190
GenomeReviews: AE005672_GR
KEGG: spn:SP_0156
TIGR: SP_0156
HOGENOM: HBG697249
OMA: MNENVAS
ProtClustDB: CLSK883918
BioCyc: SPNE170187-1:SP_0156-MONOMER
Taxonomy ID 170187
Gene Starting Position 153579
Gene Ending Position 154865
Gene Strand (Orientation) +
Protein Name DNA-binding response regulator
DNA Sequence 
>gi|194172857:153579-154865 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGTATAAAGTATTATTAGTAGATGATGAGTACATGGTGACAGAAGGTCTGAAGCGTTTGATTCCCTTT
GATAAGTGGGATATGGAGGTCGTCGCAACAGCCAGTCATGCCGATGAAGCTCTAGAATATGTTCAGGAAA
ATCCTGTCGATGTCATCATTTCCGATGTCAATATGCCAGACAAAACAGGGCTTGATATGATTCGGGAGAT
GAAAGAGATCTTACCAGATGCTGCCTATATCCTGCTCTCAGGTTATCAGGAGTTTGATTATGTAAAAAGA
GCAATGAACCTTAGTGTGGTGGACTATTTGGTCAAGCCTGTTGATAAGGTAGAGCTGGGAAATCTGCTGG
AGAAGATTGCAGGTCAGCTCGGCGAGAGAGGGAAGAAAAGTCAGACTCTTAGTCAAGAATTAGACGAGGC
TGGATTTGTTAGTTATTTAGGGGATAAGGAGAATTGGTGGATAGGTCTATCCAAGGAAAAACAAGGTTCC
TTCACCATTCCCTACTATGTCTTGGGTCAAGACTGGCAGATTTTCATTTCTGGCCACCCCCTAGATGGTT
TAGTCGTTACACCTTTTGAAGCTCCTTATCAAGAACACTTTGAACGCTGGAAGCTGAATGCTGAGAAAAC
CCTCTTTTACGGTTCTGTAAATCTGCAGCAGTCTGAGAGTCTCTTTGCCTATTACGAACCGATTTATAGG
GTTATCATTCAGGGAAATCTCAATCAAATCGTAGAAGAGTTAAATCTCTTGGAGAAGGTAGTTCTTGAAA
ATACACCTCGTGTTTCGATTACTAAACAGCTTTTTATCCAGTTTGTCATGGATGTTTTCCATTTATTTGA
ACATCTCAAAGCTGATGATATGACGGACATTGTCAAAACCATTCATGCTATTCAATCCTTCGATGAATTG
GTTTCTTATATCAAGGAAACTCTGATCAGCTTTTTCGGTCAATACCGTATGAATGAAAATGTGGTCAGTG
TGCTGGAAGTCATTGGTCGTGATTACCAAAAAGAGCTTTCCCTCAAGGATATCAGTAAGGCCCTCTTTAT
CAATCCTGTCTATCTAGGGCAGTTGATTAAGCGTGAAACCGATTCGACCTTTGCAGAGTTACTAAACAAA
CAACGTATTAAGGCTGCCCAGCAGCTCTTGCTTTCAACTAGTGACAGTATCGAAGATATTTGTTATGCTG
TTGGTTACAGTAACCTTGGATATTTCTATAAAGTTTTCCGAAAATTGTGCGGAAAATCGCCAAAAGCCTA
CCGAAAACAGGTAGAAACTATACTATA
Protein Sequence 
>gi|15900094|ref|NP_344698.1| DNA-binding response regulator [Streptococcus pneumoniae TIGR4] MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYVQENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDYLVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEKQGSFTIPYYVLGQDWQIFISGHPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNLQQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVFHLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRDYQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIEDICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0156 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG4753T, under T: Signal transduction mechanisms
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].