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SP_0121

Victor ID 3149
Gene Name SP_0121
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 929900
NCBI Protein GI 15900063
Locus Tag SP_0121
Protein Accession NP_344667.1
Other Database IDs UniProtKB-ID: Q97T35_STRPN
UniRef100: UniRef100_E0SUI6
UniRef90: UniRef90_C1CP07
UniRef50: UniRef50_Q49WL3
UniParc: UPI000003EFDC
EMBL: AE005672
EMBL-CDS: AAK74307.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000027175.
EnsemblGenome_TRS: EBSTRT00000027175
EnsemblGenome_PRO: EBSTRP00000026267
GenomeReviews: AE005672_GR
KEGG: spn:SP_0121
TIGR: SP_0121
HOGENOM: HBG497378
OMA: THRQISI
ProtClustDB: CLSK876720
BioCyc: SPNE170187-1:SP_0121-MONOMER
Taxonomy ID 170187
Gene Starting Position 125050
Gene Ending Position 126729
Gene Strand (Orientation) -
Protein Name metallo-beta-lactamase superfamily protein
DNA Sequence 
>gi|194172857:125050-126729 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTATTCTTCATCTGGTGTGAGGATCATCGGGATGATGATCGGTTCACGTTCGGTATTTTCATAGAGGAA
GGGGCGAATAGCGTTGACAATGGCACCATTGACAGATTGCACGCTAGCATCCTTATTTTTCAGTGCGATA
CGAATGGCATTGAAGAGGATACGCTGGCTTTGGCGAATCAAGTCGCCAGACTCTCTCATGTAGACAAAGC
CTCGGCTGAGGATGTCTGGACCAGATAGAATCATCTGCGATTTGAAGTCAACAGTTGCAACTGCCAGAAC
GACACCGTCTTCAGATAGATCGCGACGATCTTTGAGGACAGCTGCGCCAATTTCACCGATACGATTTCCA
TCGACATAGATATCTTGGGCGTTGAAATGACCTGCGATACGAGCTGAGTCAGCAGTAAGGGCAAGCACAT
CGCCATTGCTCATGATAAAGATATTGTCCTTCTCAACACCAGTATCCACTGCTAGTCCAGCGTGGACTTT
TTGCATGCGGTATTCACCGTGGACAGGCATGAAGTATTTTGGCTTAATCAAGCAGAGCATGAGTTTTTGC
TCTTGCTGACCACCGTGTCCAGATGTATGGATATTGTTCACTTTACCGTGGATAACTTCGACACCAGCTT
CAGAAATGATGTTAATCAGCTTGTTGACACTAGTAGTGTTTCCAGGGATGGGACTAGAAGAGAAGATAAC
GGTATCACCTGGTTGTAATTGTACTTGACGGTGGGTTCCGTTGGCGATACGAGAGAGGGCTGCCATAGGC
TCACCCTGACTACCTGTACAGAGGATAAGAACTTCTCCTGCAGGATAATCTTTGATTTCATTTGGCTCGA
TAAAGGTTCCCTTAGGAGCTTTGATGTAGCCAAGATCGATTCCGTTGACAATGGCCTTTTCCATAGAACG
ACCAAAGACCGCAATCTTGCGTCCAGTCTTAACAGCAGCTTCTGTTGCCTGCTGGAGACGGAAGATATTT
GAGGCAAAGGATGCAAAGATGATACGTCCTTCAATACCTTGGATAATCTTCATAATGGACTGACCAACGA
CTTTTTCAGAGTTGGTAAAGGTTGGTACTTCCGCATTTGTCGAGTCAGACAGGAGACAGAGCACGCCTTC
TTCACCAAGCGCAGCCATACGATGCAAGTCCGCAGGTTCTCCAACTGGAGTAAAGTCGAACTTAAAGTCA
CCCGTACAGACGATTTTCCCTTGAGGAGTATGAATGACAATCCCCAAAGGCTCTGGAATAGAGTGAGTCG
TTCTAAAGAAAGTTGCCTTGAGATTTTTAAAGGTCAACTCGGTGTTGTGGTTGATTTCGTAAAGTTTGGC
GTTGCGCAAGAGGCCGTGTTCTTCGAGTTTCCCACGGATCAAAGCCAAGGCAAGCGGTCCAGCATAAATA
GGGACATTTGCTTGCTTGAGTAGGAACGGAATCCCACCAATGTGGTCCTCGTGTCCGTGTGTGATTAAAA
CAGCCTTGACGCGGTCGATATTGTCCACGATGTAAGAGTAGTCAGGAATGACATAGTCGATACCAAGCAA
GTCATCTTCTGGGAATTTAATCCCAGCATCGACGATGATAATCTCGTCTTGGTATTCAATTCCGTAAGTG
TTTTTCCCGATTTCTCCTAGACCACCGATGGCAAAAACGCCGACTTCTTCAGGTTTAAGAGTGTAGGCCA
Protein Sequence 
>gi|15900063|ref|NP_344667.1| metallo-beta-lactamase superfamily protein [Streptococcus pneumoniae TIGR4] MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFPEDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLALALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKIVCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMKIIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAPKGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSPIPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHGEYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGEIGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRILFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0121 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0595R, under R: General function prediction only
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].