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SP_2239

Victor ID 3134
Gene Name SP_2239
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 929800
NCBI Protein GI 15902042
Locus Tag SP_2239
Protein Accession NP_346646.1
Other Database IDs UniProtKB-ID: Q97N37_STRPN
UniRef100: UniRef100_D6ZP47
UniRef90: UniRef90_E0SZH3
UniRef50: UniRef50_Q9LA06
UniParc: UPI00000C9D10
EMBL: AE005672
EMBL-CDS: AAK76286.1
RefSeq_NT: NC_003028.3
HSSP: O43464
MEROPS: S01.447
EnsemblGenome: EBSTRG00000026059.
EnsemblGenome_TRS: EBSTRT00000026059
EnsemblGenome_PRO: EBSTRP00000025151
GenomeReviews: AE005672_GR
KEGG: spn:SP_2239
TIGR: SP_2239
HOGENOM: HBG585708
OMA: YYRDGKS
ProtClustDB: CLSK2460826
BioCyc: SPNE170187-1:SP_2239-MONOMER
Taxonomy ID 170187
Gene Starting Position 2158828
Gene Ending Position 2160009
Gene Strand (Orientation) +
Protein Name serine protease
DNA Sequence 
>gi|194172857:2158828-2160009 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGAAACATCTAAAAACATTTTACAAAAAATGGTTTCAATTATTAGTCGTTATCGTCATTAGCTTTTTT
AGTGGAGCCTTGGGTAGTTTTTCAATAACTCAACTAACTCAAAAAAGTAGTGTAAACAACTCTAACAACA
ATAGTACTATTACACAAACTGCCTATAAGAACGAAAATTCAACAACACAGGCTGTTAACAAAGTAAAAGA
TGCTGTTGTTTCTGTTATTACTTATTCGGCAAACAGACAAAATAGCGTATTTGGCAATGATGATACTGAC
ACAGATTCTCAGCGAATCTCTAGTGAAGGATCTGGAGTTATTTATAAAAAGAATGATAAAGAAGCTTACA
TCGTCACCAACAATCACGTTATTAATGGCGCCAGCAAAGTAGATATTCGATTGTCAGATGGGACTAAAGT
ACCTGGAGAAATTGTCGGAGCTGACACTTTCTCTGATATTGCTGTCGTCAAAATCTCTTCAGAAAAAGTG
ACAACAGTAGCTGAGTTTGGTGATTCTAGTAAGTTAACTGTAGGAGAAACTGCTATTGCCATCGGTAGCC
CGTTAGGTTCTGAATATGCAAATACTGTCACTCAAGGTATCGTATCCAGTCTCAATAGAAATGTATCCTT
AAAATCGGAAGATGGACAAGCTATTTCTACAAAAGCCATCCAAACTGATACTGCTATTAACCCAGGTAAC
TCTGGCGGCCCACTGATCAATATTCAAGGGCAGGTTATCGGAATTACCTCAAGTAAAATTGCTACAAATG
GAGGAACATCTGTAGAAGGTCTTGGTTTCGCAATTCCTGCAAATGATGCTATCAATATTATTGAACAGTT
AGAAAAAAACGGAAAAGTGACGCGTCCAGCTTTGGGAATCCAGATGGTTAATTTATCTAATGTGAGTACA
AGCGACATCAGAAGACTCAATATTCCAAGTAATGTTACATCTGGTGTAATTGTTCGTTCGGTACAAAGTA
ATATGCCTGCCAATGGTCACCTTGAAAAATACGATGTAATTACAAAAGTAGATGACAAAGAGATTGCTTC
ATCAACAGACTTACAAAGTGCTCTTTACAACCATTCTATCGGAGACACCATTAAGATAACCTACTATCGT
AACGGGAAAGAAGAAACTACCTCTATCAAACTTAACAAGAGTTCAGGTGATTTAGAATCTTA
Protein Sequence 
>gi|15902042|ref|NP_346646.1| serine protease [Streptococcus pneumoniae TIGR4] MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNSNNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSEGSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISSEKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAISTKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINIIEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHLEKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLES
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2239 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0265O, under O: Posttranslational modification, protein turnover, chaperones
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].