Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

SP_1976

Victor ID 3133
Gene Name SP_1976
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 929784
NCBI Protein GI 15901799
Locus Tag SP_1976
Protein Accession NP_346403.1
Other Database IDs UniProtKB-ID: Q97NP4_STRPN
UniRef100: UniRef100_B1I8S9
UniRef90: UniRef90_A3CPM6
UniRef50: UniRef50_O68575
UniParc: UPI0000051A7F
EMBL: AE005672
EMBL-CDS: AAK76043.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025873.
EnsemblGenome_TRS: EBSTRT00000025873
EnsemblGenome_PRO: EBSTRP00000024965
GenomeReviews: AE005672_GR
KEGG: spn:SP_1976
TIGR: SP_1976
HOGENOM: HBG554871
OMA: DELLDNT
ProtClustDB: CLSK876928
BioCyc: SPNE170187-1:SP_1976-MONOMER
Taxonomy ID 170187
Gene Starting Position 1880925
Gene Ending Position 1881719
Gene Strand (Orientation) -
Protein Name pyruvate formate-lyase-activating enzyme
DNA Sequence 
>gi|194172857:1880925-1881719 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TCTATCCATGTACACGTTTCATATAATCTTGATAACTTTCGGTATCCATGAGTTGTTTAGCGTTCTTGAC
GCGATCTGCTGTTGGTGGTTTGACTCCTTCGAGGGAATATGGAATTCCAAGTTCACGCCACTTGAACTCA
CCCATGGTGTGATAAGGTAGAATTTCAAACTTATCAACATTTTTGAGGGTCTTGACGAACTTACCAAGTT
CAATCAAGTCATCATCTCTGTCTGTCAATCCTGGAACTAGCACGTGGCGAATCCAGACAGGTTTTCCAAT
ATCTGATAGATACTGGGCACAAGCCAAGATATTTTTATTGGTTTGGCTAGTGACAATCTTGTGCTGTTCT
TCGTTGATTTCCTTGATATCCAAAAGAACCAAGTCAGTGACAGCCATGAGTTTGTCAAACTTCTCAAGGT
AACGTGGTTTATTACGGAAAGGAAGAGCACAGGTGTCCAAGGTACAGTGGATTCCTTGTTCCTTAGCCTT
GGTGAAGAGAGCAATCAGGAAATCAATCTGCAAGAGAGCTTCTCCTCCACTGACTGTAATCCCACCCTTA
TTTCCCCAGAAACCACGGTAGCGCAAGGCCTCTGTCAAGACATCATCTACCGTCCGTTCACGTGACTTAT
TGGACTCCATAGCCCAAGTGTCTGGGTTGTGGCAATACTGGCAACGCATGTGACAGCCCTGCAAAAAGAC
AATAAAGCGAATACCAGGCCCATCTACTGACCCAAAGCTTTCTGTCGAATGCACCATTCCTGTCACTTGT
CCATAATCAATTGTTTCTTCAGACA
Protein Sequence 
>gi|15901799|ref|NP_346403.1| pyruvate formate-lyase-activating enzyme [Streptococcus pneumoniae TIGR4] MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQYCHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFTKAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTNKNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTMGEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1976 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1180O, under O: Posttranslational modification, protein turnover, chaperones
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].