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cbpD from Streptococcus pneumoniae R6

Victor ID 3131
Gene Name cbpD from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism) Streptococcus pneumoniae R6
NCBI Gene ID 934859
NCBI Protein GI 15904047
Locus Tag spr2006
Protein Accession NP_359597.1
Other Database IDs UniProtKB-ID: Q8DMZ4_STRR6
UniRef100: UniRef100_Q8DMZ4
UniRef90: UniRef90_B1IA13
UniRef50: UniRef50_Q8DMZ4
UniParc: UPI00000E3768
EMBL: AE007317
EMBL-CDS: AAL00808.1
RefSeq_NT: NC_003098.1
HSSP: P06653
EnsemblGenome: EBSTRG00000014668.
EnsemblGenome_TRS: EBSTRT00000014668
EnsemblGenome_PRO: EBSTRP00000014064
GenomeReviews: AE007317_GR
KEGG: spr:spr2006
eggNOG: COG3942
HOGENOM: HBG702133
OMA: RVIKANT
ProtClustDB: CLSK803921
BioCyc: SPNE171101:SPR2006-MONOMER
Taxonomy ID 171101
Gene Starting Position 1999011
Gene Ending Position 2000357
Gene Strand (Orientation) -
Protein Name Choline binding protein D
DNA Sequence 
>gi|15902044:1999011-2000357 Streptococcus pneumoniae R6, complete genome
TCTATACTCGTTCTCCATCACTGTTTACTCTGTAGCCATCCACCGTCGTATTAATAGCTAAGGCGCCTGA
AGAGTAAGAATAATACCACTCACCAGAGACCTGGTACCAGCCTGTTTTCATTGCCCCTGAACTACCCAGA
TAATACCACGAGCCATTCTCCTTTAACCATCCTGTCTGCATTTCACCAGATAATTTCAAATAATACCAGC
TAGAACCGTCTTTCAGCCATCCTGTTGATTTAGAACCATTTGATTTGAAATGATACCAACTACCATTTAT
TTTCTTCCAACCGACAGTTGAACTATTATTGGATCCATAGCTAGAGATATTTCCTGATTGATTCTGATAA
TTTTGTGAAGAAGTCACTCCCTCTAGCTGTATATAGCGACGACTTCCGTTATAAGCCGTATAACTCAACC
ACTTATAGCCGTCTTTTTCAAGTATCTGATCATAATGAACCTTCTCTCCAGGATAATAGTAATCAATCAC
AGTTGCACTAACTAGGGGTTCAGTTTTAATAGCAGACTTGATCTTAAAATAATGAGTTCCTCCTGTTGAA
GAAAGAACAGAATTACCTAGAGGATTTTTATTCACAGCCTCCAATTGAACATAACGATAGCTTCCATTAT
AGGCAGTATAACTCAACCACTTATAGCCGTCTTTTTCAAGTATCTGATCATAATGAACCTTCTCCCCAGG
ATAATAGTAATCAATCACAGTTGCACTAACTAGGGGTTCAGTTTTAATAGCAGACTTGGTCTTAAAATAA
TGAGTTCCGCCTGTTGAAGCTGAGGATTGACTATTCCCAACACTGCCACTATCCAAATCTTTAAAATGAA
TAAATCCTGTCATCGTGTTTGCTTTTATAACTCGTTTATTATAGGATTCTGTATAACCATAGTTATATTC
CTCAATCTCAATCTGATCTCCCATTACATTTGACACCCAGGCAACATGACCATAAGTTCCTGCAGTAGAC
CAAGTAATGGAACCAATCGTCGGTGTATTATCTACACGATAACCTTCCCGACGAGCACGATGTCCCCATT
CATTCGCATTTCCATAAGCTGCCGGAATTTCAAAACCATTGACATTACTCAAACGAAAGGCTACAAAAGA
AGTACACTGACGAGAATACATGCGCCACTGATCAATCTCCTGGCTCCCATTTTTATAATAAGCAGGATAA
TCATCCCCACGCGCAATCGATCCATTTCCTCTGGAATAGGCATAGACACTATCACCAGCTGCTAGCATCA
ATCCTACTACTAAAAAAGGAACAAGCTTTTTAACTGACATCTTCAAGTAATAACTTGTTCCTCTTGCTAT
AAACGGTAAAATTTTCA
Protein Sequence 
>gi|15904047|ref|NP_359597.1| choline binding protein D [Streptococcus pneumoniae R6] MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRGNGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRVIKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSAIKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGEWYYSYSSGALAINTTVDGYRVNSDGERV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cbpD has reduced colonization of nasopharynx of rats compared to the wild type (Gosink et al., 2000).
COG COG3942R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].