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lipF from Mycobacterium tuberculosis H37Rv

Victor ID 313
Gene Name lipF from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888430
NCBI Protein GI 15610623
Locus Tag Rv3487c
Protein Accession NP_218004.1
Other Database IDs UniProtKB-ID: O06350_MYCTU
UniRef100: UniRef100_A5U8G2
UniRef90: UniRef90_A5U8G2
UniRef50: UniRef50_A5U8G2
UniParc: UPI0000036B92
EMBL: BX842583
EMBL-CDS: CAB08710.1
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000002038.
EnsemblGenome_TRS: EBMYCT00000002040
EnsemblGenome_PRO: EBMYCP00000002040
GenomeReviews: AL123456_GR
KEGG: mtu:Rv3487c
TubercuList: Rv3487c
HOGENOM: HBG757640
OMA: NSHRALA
ProtClustDB: CLSK790935
Taxonomy ID 83332
Gene Starting Position 3906173
Gene Ending Position 3907006
Gene Strand (Orientation) -
Protein Name PROBABLE ESTERASE/LIPASE LIPF
DNA Sequence 
>gi|57116681:3906173-3907006 Mycobacterium tuberculosis H37Rv, complete genome
ACTAGATAGGCGACTGTCCAAACGCGCCACGGCTTGCGGCGCGAGGTGAACCCGCGACGTAGCGCGACCG
ATGCACCGGACTCAACGACGAGTCAGCGGTGGCGTCGCGAATGAACTGCCCGATCTGACGCAACGAACGG
GTCGCTTCGGGCACCAGCGGTGTGGCGAGTTGGAAAAGATGAGCCTGACCGGGCCAAACCCGTACCTCGG
CACAGACGCCTGCCGCCGCCAGCTTGCCGGCGCCCAGCTGCGCGTCGTGCAGCAGCACTTCGGAGCCGGA
AACGTGAATAAGTGTCGGCGGCAAGCTGGATTCGATATGGTCGAGCGGCTCATAGAGGTCTTCGGGCCTG
CCGTCGACCATGTTCTTGGCAGCGGCCGCCCTGACCCATGCCGCCAAGGCATCGAATGCCCGCGCCGGAA
ACATCGCGTCGGTCCCGATGTTGGGATGGTCCTGCTTGGGCCCCTTGGCCAGCTGCAGCAACGGAGAGAT
GGCCACTATTGCCGCCGGTTTCTCGTCGTCGCACTGCAGCCGCTGCGCAAGCGCGAGCGCAAGGTAACCA
CCCGCGGAATCACCGGCCAACACGATCTGTTCCGGCCGGTATCCGCGCGCCCGCAACCATTGGTATGCAT
CGTGGCAGTCGTCGAGCGCCATCCCCAGCGAATGCTTAGGGATCAGCCGATAGTCGACTATCAACACGGG
TGATTCGGCAAATCCTGACAGCGCGTTGACGATCCTGCTGTGCGAATTCGGCCCGCACATGACAAACGCG
CCGCCGTGCAAATAGAGCACCACCCGCCCAGCGCCGTCGGCCGCCCGCACCCCAGGCGCACGCA
Protein Sequence 
>gi|448824815|ref|NP_218004.3| carboxylesterase LipF [Mycobacterium tuberculosis H37Rv] MRAPGVRAADGAGRVVLYLHGGAFVMCGPNSHSRIVNALSGFAESPVLIVDYRLIPKHSLGMALDDCHDAYQWLRARGYRPEQIVLAGDSAGGYLALALAQRLQCDDEKPAAIVAISPLLQLAKGPKQDHPNIGTDAMFPARAFDALAAWVRAAAAKNMVDGRPEDLYEPLDHIESSLPPTLIHVSGSEVLLHDAQLGAGKLAAAGVCAEVRVWPGQAHLFQLATPLVPEATRSLRQIGQFIRDATADSSLSPVHRSRYVAGSPRAASRGAFGQSPI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lipF mutant is attenuated in mice lungs (Camacho et al., 1999).
COG COG0657I, under I: Lipid transport and metabolism
References
Camacho et al., 1999: Camacho LR, Ensergueix D, Perez E, Gicquel B, Guilhot C. Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis. Molecular microbiology. 1999; 34(2); 257-267. [PubMed: 10564470].