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regR from Streptococcus pneumoniae R6

Victor ID 3127
Gene Name regR from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism) Streptococcus pneumoniae R6
NCBI Gene ID 934722
NCBI Protein GI 15902342
Locus Tag spr0298
Protein Accession NP_357892.1
Other Database IDs UniProtKB-ID: Q8DR72_STRR6
UniRef100: UniRef100_Q8DR72
UniRef90: UniRef90_B2ISP9
UniRef50: UniRef50_D6ZQH0
UniParc: UPI00000E3406
EMBL: AE007317
EMBL-CDS: AAK99102.1
RefSeq_NT: NC_003098.1
HSSP: P15039
EnsemblGenome: EBSTRG00000016188.
EnsemblGenome_TRS: EBSTRT00000016188
EnsemblGenome_PRO: EBSTRP00000015584
GenomeReviews: AE007317_GR
KEGG: spr:spr0298
eggNOG: COG1609
HOGENOM: HBG753640
OMA: ISISRRC
ProtClustDB: CLSK797399
BioCyc: SPNE171101:SPR0298-MONOMER
Taxonomy ID 171101
Gene Starting Position 298846
Gene Ending Position 299913
Gene Strand (Orientation) +
Protein Name Transcription regulator, member of GalR family
DNA Sequence 
>gi|15902044:298846-299913 Streptococcus pneumoniae R6, complete genome
AGTGCTAGAAATAGGCATTTTGAATAGTGAATATGTTATAATAAGTATTAGTAGGAGGTGTTTTAGATTG
GAGAAGAAACTGACCATAAAAGACATTGCGGAAATGGCTCAGACCTCGAAAACAACCGTGTCATTTTACC
TAAACGGGAAATATGAAAAAATGTCCCAAGAGACACGTGAAAAGATTGAAAAAGTTATTCATGAAACAAA
TTACAAACCGAGCATTGTTGCGCGTAGCTTAAACTCCAAACGAACAAAATTAATCGGTGTTTTGATCGGT
GATATTACCAACAGTTTCTCAAACCAAATTGTTAAGGGAATTGAGGATATCGCCAGCCAGAATGGCTACC
AGGTAATGATAGGAAATAGTAATTACAGCCAAGAGAGTGAGGACCGGTATATTGAAAGCATGCTTCTCTT
GGGAGTAGACGGCTTTATTATTCAGCCGACCTCTAATTTCCGAAAATATTCTCGTATCATCGATGAGAAA
AAGAAGAAAATGGTCTTTTTTGATAGTCAGCTCTATGAACACCGGACTAGCTGGGTTAAAACCAATAACT
ATGATGCCGTTTATGACATGACCCAGTCCTGTATCGAAAAAGGTTATGAGTATTTTCTCTTGATTACAGC
GGATACGAGTCGTTTGAGTACTCGGATTGAGCGGGCAAGTGGTTTTGTGGATGCTTTAACAGATGCTAAT
ATGCGTCACGCCAGTCTAACCATTGAAGATAAGCATACGAATTTGGAACAAATTAAGGAATTTTTACAAA
AAGAAATCGATCCCGATGAAAAAACTCTGGTATTTATCCCTAACTGTTGGGCCCTACCTCTAGTCTTTAC
CGTTATCAAAGAGTTGAATTATAACTTGCCGCAAGTTGGGTTGATTGGTTTTGACAATACGGAGTGGACT
TGCTTTTCTTCTCCAAGTGTTTCGACGCTGGTTCAGCCCTCCTTTGAGGAAGGACAACAGGCTACAAAGA
TTTTGATTGACCAGATTGAAGGCCGCAATCAAGAAGAAAGGCAACAAGTCTTGGATTGTAGTGTGAATTG
GAAAGAGTCGACTTTCTA
Protein Sequence 
>gi|15902342|ref|NP_357892.1| GalR family transcription regulator [Streptococcus pneumoniae R6] MLEIGILNSEYVIISISRRCFRLEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVIHETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSNYSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWVKTNNYDAVYDMTQSCIEKGYEYFLLITADTSRLSTRIERASGFVDALTDANMRHASLTIEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFDNTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: regR mutant is attenuated in mice (Chapuy-Regaud et al., 2003).
COG COG1609K, under K: Transcription
References
Chapuy-Regaud et al., 2003: Chapuy-Regaud S, Ogunniyi AD, Diallo N, Huet Y, Desnottes JF, Paton JC, Escaich S, Trombe MC. RegR, a global LacI/GalR family regulator, modulates virulence and competence in Streptococcus pneumoniae. Infection and immunity. 2003; 71(5); 2615-2625. [PubMed: 12704136].