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pgdA from Streptococcus pneumoniae R6

Victor ID 3125
Gene Name pgdA from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism) Streptococcus pneumoniae R6
NCBI Gene ID 934547
NCBI Protein GI 15903376
Locus Tag spr1333
Protein Accession NP_358926.1
Other Database IDs UniProtKB-ID: Q8DP63_STRR6
UniRef100: UniRef100_Q04JM3
UniRef90: UniRef90_Q04JM3
UniRef50: UniRef50_Q04JM3
UniParc: UPI00000B8C38
EMBL: AE007317
EMBL-CDS: AAL00137.1
RefSeq_NT: NC_003098.1
PDB: 2C1G
PDB: 2C1I
EnsemblGenome: EBSTRG00000015857.
EnsemblGenome_TRS: EBSTRT00000015857
EnsemblGenome_PRO: EBSTRP00000015253
GenomeReviews: AE007317_GR
KEGG: spr:spr1333
eggNOG: COG0726
HOGENOM: HBG703418
OMA: AHELYYS
ProtClustDB: CLSK884105
BioCyc: SPNE171101:SPR1333-MONOMER
Taxonomy ID 171101
Gene Starting Position 1319729
Gene Ending Position 1321120
Gene Strand (Orientation) -
Protein Name Peptidoglycan GlcNAc deacetylase
DNA Sequence 
>gi|15902044:1319729-1321120 Streptococcus pneumoniae R6, complete genome
CTTATTCATCACGACTATAGTACAGCTCATGAGCTTTTAGGCGAGTATTGAGCATCTCTGGTATGGTCAC
AAAGGTATAACCTTGATTTTTCAAATACTCAATGACCCTTGGCAAGGCATTGACTGTCGGACTGTGAATA
TCATGCATCAAAACGATAGAGCCATTAGCTACTTGATGCTGAATTTCTGTCAAAATAGATGCTTCATTTT
TACTCTTCCAGTCCAGACTATCCACATCCCACATGATAAAGCTCAAATCCAAGCTATTGCGAATATCATC
TGTAATAGCACCATAAGGTGGACGCATGAGTTTAGAACTAGAACCCAGCACTTTAGTTAGCACATCCTCA
GTATCAGTAATCTGCTTTTTAGCTTCATCAAGAGAGAGTTGCGAGAGAATCGGATGGCTCCAGCTATGGT
TTCCAACAACATGACCTTCAGATTTTATCCTCTTCACCAAGTCCTCATTCCCAGAAACATTTTTCCCAAG
CACAAAGAAAGTCGCTTTAATATCATATTTAGCTAGGGTCTCTAATACCTGCGGGGTCGTTGCTGGATTT
GGACCATCATCAAAGGTTAGAGCGACAACTTTTTGATGTTTCTTATCAAAGTAAGATTGGTACAAGGCCG
CATCTTTTTCGAGTAAGTACGAAGATTGGATAACATCAAAGAAAGCAGATACTGGCAAGGCTATCTCTTC
TAAATTTTCAACCACAGGACTTGGATAAAGGATAATCTGACTATCCTTGTAATCAAAATTCCATGCAGAC
AAGTCTTGGTCAGAGAAGTTTTTTACAATCTGCTCACTCTGGTCTTGCTCTATTTTTTTATCCTCTATGA
AGGAGGTCAACTCTTTTATCAGCTGTTCCTTAGCCTTACTAGCATCTGAAAACAGTTGGTCAAGTGTAAA
AGGTTGCCCATCTTCTGTTAAGTGAACCTTTCCTAGACTGGTCTTTTCAGTCTCTTCAATCTTAAAAGCA
ACTAAATCATAGATTTGTTTGGTCACATTACGATTAACGACTCCCTTTAAACCTGACTCTTCTTGCTCTG
TATAGTAGAAAACAAGATTGTCCTTACTTTCTAGCTTGTCCTTAACATCTTGATTTATCAGCTCCCTAAC
AGAGGAAATCACTTTCTCCCCTTGGAGAGGATAATAGGCAATCACTTCGGCTTGCCCCTGACGAAAATGC
TCCTTCTGATTTCCCTCACTCAATTGATCATCTTTCTCTTTTTTGAGCGATTCAATCTTTTGCTCAAAAC
TTTTTTGCTGGTAGATCTTAAAAGCAATAAATCCGCCTAATAGGCAAATAGAAATTGCTAAAATACCAAT
CAAAGCCAATAATACATGTCTCGTTTTCCCGTGTCTGCCACGTCCTAGTCTACTTTTATTCA
Protein Sequence 
>gi|15903376|ref|NP_358926.1| peptidoglycan GlcNAc deacetylase [Streptococcus pneumoniae R6] MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQKSFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKDKLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDDGPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILSQLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNTRLKAHELYYSRDE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pgdA mutant is attenuated in mice (Vollmer and Tomasz, 2002).
COG COG0726G, under G: Carbohydrate transport and metabolism
References
Vollmer and Tomasz, 2002: Vollmer W, Tomasz A. Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae. Infection and immunity. 2002; 70(12); 7176-7178. [PubMed: 12438406].