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nox from Streptococcus pneumoniae R6

Victor ID 3124
Gene Name nox from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism) Streptococcus pneumoniae R6
NCBI Gene ID 934540
NCBI Protein GI 15903366
Locus Tag spr1323
Protein Accession NP_358916.1
Other Database IDs UniProtKB-ID: Q8DP70_STRR6
UniRef100: UniRef100_Q8DP70
UniRef90: UniRef90_B2IQT6
UniRef50: UniRef50_A2RIB7
UniParc: UPI00000E3632
EMBL: AE007317
EMBL-CDS: AAL00127.1
RefSeq_NT: NC_003098.1
HSSP: P37062
EnsemblGenome: EBSTRG00000015522.
EnsemblGenome_TRS: EBSTRT00000015522
EnsemblGenome_PRO: EBSTRP00000014918
GenomeReviews: AE007317_GR
KEGG: spr:spr1323
eggNOG: COG0446
HOGENOM: HBG535576
OMA: FFFQPHF
ProtClustDB: CLSK877163
BioCyc: SPNE171101:SPR1323-MONOMER
Taxonomy ID 171101
Gene Starting Position 1309394
Gene Ending Position 1310773
Gene Strand (Orientation) -
Protein Name NADH oxidase
DNA Sequence 
>gi|15902044:1309394-1310773 Streptococcus pneumoniae R6, complete genome
TTTATTTTTCAGCCGTAAGGGCAGCCATTGTGATGTAGTTGTATGGTTTGTTGAAGTGTGGCAAGAAGAA
GAGGTCTGTCAATGCCAATTTATCAATTGTCACATGCTCTTGGATAGCAAGTGAGAACATGTGGATTCCC
ATGCTAATTGCAATATCATGTGAAACCATTTGGGCACCAAGAATTTCACGGCTATCTTTGTCAAAGACAA
TCTTAATTGCTACTTCATGGTTGTCATGTTTCATGAATTCTGGTTTTTGAAGATCGTTAAAGCCTGTTTC
AGTTGCGTTGTAACCAGCAGCTTTCGCTTTTTCAAGAGTCAAACCAGTTGAAACCATGTGAAGACCGTAG
ATTGAGATACCATTTGAACCTTGAACACCGATTCCTTCCAATTCATGTCCACAAGCGTTGTAGGCACCAA
CGATACCAGTGCGAACAGCATTTGAAGCAAGAGCGATATAGCTTGTATCTTTACGAGCATTGTCATAAAC
AGTCGCACAGTCACCAACAGCGTAAACGCCTGGGATAGATGTTTCTTGTTTCTTGTCTACAAGGAAGGCA
CCGTTGCGGAAGAGTTCGATCTTACCATCTGCAAGGGCTGTGTTTGGACGGAAACCAACTGCAAGGATAA
CCATATCCACGTCAAAGCTTTCTTTGTCAGTAATCAAGCGTTCAACTTTACCGTCACCTTCGATTGCTTT
AACAGTTTGACCTAGAGCCAAGCGGATGTTGTGATCTTCCAAGTTCTTCGCCATCATTTGTGTGAAGTCT
TTGTCATAGTAACCGTTCAAGACAGTATCAACGATATCAACAAGGACAACTTCTTTTCCAAGACGTTCAA
AGGCTTCAGCAAGTTCAACACCGATGTAACCACCACCAACAACGGCGATACGGTCGAGGTGTTGGCTCTT
GTCAGAAAGTTTATTGATAACTTCTTCAGCATTTTGGTACAATTTCACGAATTGTACGTTTTCAAGAGTT
GCTTTAAATTCGCGGTTTCCTTTAACAATTTCAACACCTTCGATTGGTGGCAAGATTGGTGTAGAACCTG
TAGCGAAAATCAATTTTTCGTATGATTCTTTGTGCTCTTTTCCTTCAACTTCCGCTGTAACTACTTTGGC
ATCATAGTCGATTGAAAGAACAGGTGAGTTCATGTAAACTTTAGCACCTTTAGCTTCCAATTTTTCTTTA
TCAGAATAGAACAAGCCTTCAGCACCGTCAATTTGTTCACCAATCCAAAGAGCCATTCCACATCCTAGGA
AAGAGATGTTAGAGTTTTGGTCAAATACAACAATTTCGTTCTCATTTCCAAAATTATCCAACATGGTATT
GATACATGCTGTACCAGCGTGGTTAGCACCGACTACAACGATTTTACTCA
Protein Sequence 
>gi|15903366|ref|NP_358916.1| NADH oxidase [Streptococcus pneumoniae R6] MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGCGMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDAKVVTAEVEGKEHKESYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQHLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHNIRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAFLVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGIGVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIVFDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYITMAALTAEK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: nox mutant is attenuated in mice (Yu et al., 2001).
COG COG0446R, under R: General function prediction only
References
Yu et al., 2001: Yu J, Bryant AP, Marra A, Lonetto MA, Ingraham KA, Chalker AF, Holmes DJ, Holden D, Rosenberg M, McDevitt D. Characterization of the Streptococcus pneumoniae NADH oxidase that is required for infection. Microbiology (Reading, England). 2001; 147(Pt 2); 431-438. [PubMed: 11158360].