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lytB from Streptococcus pneumoniae R6

Victor ID 3122
Gene Name lytB from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism) Streptococcus pneumoniae R6
NCBI Gene ID 934406
NCBI Protein GI 15902911
Locus Tag spr0867
Protein Accession NP_358461.1
Other Database IDs UniProtKB-ID: LYTB_STRR6
UniRef100: UniRef100_P59206
UniRef90: UniRef90_P59206
UniRef50: UniRef50_P59206
UniParc: UPI000012EAA6
EMBL: AJ010312
EMBL: AE007317
EMBL-CDS: CAA09078.2
EMBL-CDS: AAK99671.1
RefSeq_NT: NC_003098.1
EnsemblGenome: EBSTRG00000014615
EnsemblGenome_TRS: EBSTRT00000014615
EnsemblGenome_PRO: EBSTRP00000014011
GenomeReviews: AE007317_GR
KEGG: spr:spr0867
eggNOG: COG5263
HOGENOM: HBG702253
ProtClustDB: CLSK559969
BioCyc: SPNE171101:SPR0867-MONOMER
Taxonomy ID 171101
Gene Starting Position 858970
Gene Ending Position 861135
Gene Strand (Orientation) +
Protein Name Endo-beta-N-acetylglucosaminidase
DNA Sequence 
>gi|15902044:858970-861135 Streptococcus pneumoniae R6, complete genome
TATGAATTTAGGAGAATTTTGGTACAATAAAATAAATAAGAACAGAGGAAGAAGGTTGATGAAGAAAGTA
AGATTTATTTTTTTAGCTCTGCTATTTTTCTTAGCTAGTCCAGAGGGTGCAATGGCTAGTGATGGTACTT
GGCAAGGAAAACAGTATCTGAAAGAAGATGGCAGTCAAGCAGCGAATGAGTGGGTTTTTGATACTCATTA
TCAATCTTGGTTCTATATAAAAGCAGATGCTAACTATGCTGAAAATGAATGGCTAAAGCAAGGTGACGAC
TATTTTTACCTCAAATCTGGTGGCTATATGGCCAAATCAGAATGGGTAGAAGACAAGGGAGCCTTTTATT
ATCTTGACCAAGATGGAAAGATGAAAAGAAATGCTTGGGTAGGAACTTCCTATGTTGGTGCAACAGGTGC
CAAAGTAATAGAAGACTGGGTCTATGATTCTCAATACGATGCTTGGTTTTATATCAAAGCAGATGGACAG
CACGCAGAGAAAGAATGGCTCCAAATTAAAGGGAAGGACTATTATTTCAAATCCGGTGGTTATCTACTGA
CAAGTCAGTGGATTAATCAAGCTTATGTGAATGCTAGTGGTGCCAAAGTACAGCAAGGTTGGCTTTTTGA
CAAACAATACCAATCTTGGTTTTACATCAAAGAAAATGGAAACTATGCTGATAAAGAATGGATTTTTGAG
AATGGTCACTATTATTATCTAAAATCCGGTGGCTACATGGCAGCCAATGAATGGATTTGGGATAAGGAAT
CTTGGTTTTATCTCAAATTTGATGGGAAAATAGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGC
TTGGTACTACTTCAAATCCGGTGGCTACATGGCAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTT
TACCTCAAGTTTGATGGCAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCCTGGTACT
ACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTATCTCAA
ATCTGATGGGAAAATAGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCTTGGTACTACTTCAAA
TCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTACCTCAAGTCTGATG
GCAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCCTGGTACTACTTCAAATCTGGTGG
CTACATGGCGAAAAATGAGACAGTAGATGGTTATCAGCTTGGAAGCGATGGTAAATGGCTTGGAGGAAAA
GCTACAAATAAAAATGCTGCTTACTATCAAGTAGTGCCTGTCACAGCCAATGTTTATGATTCAGATGGTG
AAAAGCTTTCCTATATATCGCAAGGTAGTGTCGTATGGCTAGATAAGGATAGAAAAAGTGATGACAAGCG
CTTGGCTATTACTATTTCTGGTTTGTCAGGCTATATGAAAACAGAAGATTTACAAGCGCTAGATGCTAGT
AAGGACTTTATCCCTTATTATGAGAGTGATGGCCACCGTTTTTATCACTATGTGGCTCAGAATGCTAGTA
TCCCAGTAGCTTCTCATCTTTCTGATATGGAAGTAGGCAAGAAATATTATTCGGCAGATGGCCTGCATTT
TGATGGTTTTAAGCTTGAGAATCCCTTCCTTTTCAAAGATTTAACAGAGGCTACAAACTACAGTGCTGAA
GAATTGGATAAGGTATTTAGTTTGCTAAACATTAATAATAGCCTTTTGGAGAACAAGGGCGCTACTTTTA
AGGAAGCCGAAGAACATTACCATATCAATGCCCTTTATCTCCTTGCCCATAGTGCCCTAGAAAGTAACTG
GGGAAGAAGTAAAATTGCCAAAGATAAGAATAATTTCTTTGGCATTACAGCCTATGATACGACCCCTTAC
CTTTCTGCCAAGACATTTGATGATGTGGATAAGGGAATTTTAGGTGCAACCAAGTGGATTAAGGAAAATT
ATATCGATAGGGGAAGAACTTTCCTTGGAAACAAGGCTTCTGGTATGAATGTGGAATATGCTTCAGACCC
TTATTGGGGCGAAAAAATTGCTAGTGTGATGATGAAAATCAATGAGAAGCTAGGTGGCAAAGATTA
Protein Sequence 
>gi|15902911|ref|NP_358461.1| endo-beta-N-acetylglucosaminidase [Streptococcus pneumoniae R6] MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDSHSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lytB has reduced colonization of nasopharynx of rats compared to wild type (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].