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srtA from Streptococcus pneumoniae R6

Victor ID 3115
Gene Name srtA from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism) Streptococcus pneumoniae R6
NCBI Gene ID 933969
NCBI Protein GI 15903141
Locus Tag spr1098
Protein Accession NP_358691.1
Other Database IDs UniProtKB-ID: Q8DPM3_STRR6
UniRef100: UniRef100_E0T061
UniRef90: UniRef90_E0T061
UniRef50: UniRef50_A3CN68
UniParc: UPI00000E35C5
EMBL: AE007317
EMBL-CDS: AAK99901.1
RefSeq_NT: NC_003098.1
MEROPS: C60.006
EnsemblGenome: EBSTRG00000015096.
EnsemblGenome_TRS: EBSTRT00000015096
EnsemblGenome_PRO: EBSTRP00000014492
GenomeReviews: AE007317_GR
KEGG: spr:spr1098
eggNOG: COG3764
HOGENOM: HBG517863
OMA: AGTMKED
ProtClustDB: CLSK876837
BioCyc: SPNE171101:SPR1098-MONOMER
Taxonomy ID 171101
Gene Starting Position 1094719
Gene Ending Position 1095462
Gene Strand (Orientation) -
Protein Name Sortase
DNA Sequence 
>gi|15902044:1094719-1095462 Streptococcus pneumoniae R6, complete genome
ATTAATAAAATTGTTTATATGGTTGATTGAAAGCTGTTAGGATTTCATCAGATGTTTGTGAATAATCTTT
TGTTTCTTTCAAATCACCTTTGACAATAATACGTTCTGTAGCAGCAAGGTCTTCACAGGTTACTAATGTG
ATTTCATTGACCCCATCTCTATCATCAACTTCATCAACACGATCTGGTGTCACACGTTTGACTTCACGTA
TTTCATAAGTATAAACTTTATTTTTATCGGTTAGATAAATCTTCATGCCATTTTTAGCATTATCTAAAGG
AGAAAATAACATTTTATTAGCATTATCAACACCAAAGATATGGTGACTAGCTAGACTATAATTTCCTTCT
CCCATTACTTGCTCGCGTTTCATTGTACCAGCTCCGTAGAAGAGATTAACATTATCAAGTCCTTTAAAAA
TCGGCAAATTCATTTCCAATTCAGGAATTGCAATTCCCCCAATAACTGGTAATTTTTGAGCATCCCATTG
AGAAGTTAGAACAGCTTCCGAAGAGATAGCTTTGACAGAATCAAAGTCAAAATTGCCTTCTGTATCCTGA
TTTTCTTCTAATTTTTCTTTTGATACCTGGCTAACTTGATACTTATTGGTATTCCAGACTATGAAAATAT
TTCGAATTTGAGTATTAAAAATCAAAGCCAGTGACAGTAATATCAGAAATCCTGCTAGGATATTTGTCAG
CAGATTTTTTCGCTTGTTTTTCTTTTTATTATTTTTTTGAGACA
Protein Sequence 
>gi|15903141|ref|NP_358691.1| sortase [Streptococcus pneumoniae R6] MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVWNTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPELEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNAKNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIVKGDLKETKDYSQTSDEILTAFNQPYKQFY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The srtA mutant colonized the nasopharynx of chinchillas at a significantly lower level than the wild type (Chen et al., 2005).
COG COG3764M, under M: Cell wall/membrane/envelope biogenesis
References
Chen et al., 2005: Chen S, Paterson GK, Tong HH, Mitchell TJ, DeMaria TF. Sortase A contributes to pneumococcal nasopharyngeal colonization in the chinchilla model. FEMS microbiology letters. 2005; 253(1); 151-154. [PubMed: 16246506].