Victors

zmpB from Streptococcus pneumoniae R6
Victor ID	3102
Gene Name	zmpB from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism)	Streptococcus pneumoniae R6
NCBI Gene ID	933274
NCBI Protein GI	15902625
Locus Tag	spr0581
Protein Accession	NP_358175.1
Other Database IDs	UniProtKB-ID: ZMPB_STRR6 UniRef100: UniRef100_Q8DQN5 UniRef90: UniRef90_Q8DQN5 UniRef50: UniRef50_Q8DQN5 UniParc: UPI00000E349A EMBL: AE007317 EMBL-CDS: AAK99385.1 RefSeq_NT: NC_003098.1 MEROPS: M26.002 EnsemblGenome: EBSTRG00000015854 EnsemblGenome_TRS: EBSTRT00000015854 EnsemblGenome_PRO: EBSTRP00000015250 GenomeReviews: AE007317_GR KEGG: spr:spr0581 HOGENOM: HBG697431 OMA: ESVGTTG ProtClustDB: CLSK883904 BioCyc: SPNE171101:SPR0581-MONOMER
Taxonomy ID	171101
Gene Starting Position	591446
Gene Ending Position	597076
Gene Strand (Orientation)	+
Protein Name	Zinc metalloprotease
DNA Sequence	>gi\|15902044:591446-597076 Streptococcus pneumoniae R6, complete genome AGTGTTTAAAAAAGACCGTTTTTCAATTCGTAAGATTAAGGGAGTTGTAGGCTCTGTATTTCTTGGAAGC CTTTTGATGGCTCCTTCTGTAGTGGACGCAGCCACCTATCACTATGTAAATAAAGAGATTATTTCACAAG AAGCTAAAGATTTAATTCAGACAGGAAAGCCTGACAGGAATGAAGTTGTATATGGTTTGGTGTATCAAAA AGATCAGTTGCCTCAAACAGGGACAGAAGCATCTGTTTTGACAGCTTTTGGTTTGCTGACTGTTGGGAGC TTGCTTTTAATCTACAAGAGAAAGAAAATTGCTAGCGTCTTTCTAGTTGGAACTATGGGATTGGTAGTTC TTCCTAGTGCAGGGGCTGTAGACCCAGTTGCGACCCTAGCACTGGCTAGTCGAGAGGGTGTTGTTGAAAT GGAGGGCTATCGCTATGTTGGTTATCTATCAGGTGACATCCTCAAAACGCTTGGCTTGGACACTGTTTTA GAAGAAACCTCAGCAAAACCTGGAGAGGTGACTGTAGTCGAAGTTGAGACTCCTCAATCAACAACAAATC AGGAGCAAGCTAGGACAGAAAACCAAGTAGTAGAGACAGAGGAAGCTCCAAAAGAAGAAGCACCTAAAAC AGAAGAAAGTCCAAAGGAAGAACCAAAATCGGAGGTAAAACCTACTGACGACACCCTTCCTAAAGTAGAA GAGGGGAAAGAAGATTCAGCAGAACCAGCTCCAGTTGAAGAAGTAGGTGGAGAAGTTGAGTCAAAACCAG AGGAAAAAGTAGCAGTTAAGCCAGAAAGTCAACCATCAGACAAACCAGCTGAGGAATCAAAAGTTGAACA AGCAGGTGAACCAGTCGCGCCAAGAAAAGACGAACAGGCACCAGTCGAGCCAGAAAATCAACCAGAAGCT CCTGAAGAAGAGAAGGCTGTAGAGGAAACACCGAAACAAGAAGAGTCAACTCCAGATACCAAGGCTGAAG AAACTGTAGAACCAAAAGAGGAGACTAAAACAGCTAAGGGGACGCAAGAAGAAGGCAAAGAAGGTCAAGC ACCAGTACAAGAAGTAAACCCAGAATATAAAGTAACAACAGGTACAGTTGAGAAGTCTACCGAAAGTGAA TTAGATTTCACAACAGAAGTAGTTCCGGATGACACAAAATATGTAGATGAAGAAGTTGTTGAACGTCAAG GATCTAAAGGAGTTCAAGTTACGAAAACAACTTACGAAACAGTGGAAGTTGTAGAGACAGACAAAGTCCT TTCTACAACTACAGAAGTGAAAACTCCTGTTGTTCCTAAAGTCGTTAAAAAAGGAACAAAACCAGTTGAA ACAAGAGAAGAAGTCATTCCTTTTGCTACAAAAGAACAAGAAGATGACACTTTAAAACGCGGAACAAGAC AAGTAGCTCAAGAAGGTGTAAACGGTAAGAAACAAATTACTGAAACCTATAAAACAATTCGCGGAGAAAA AACAAACGAAGCTCCAACAGTAGAAGAAACAGTTCTCCAAGCACCTCAAGATGAGATTATCAAAAAAGGT ACAAAAGGGTTAGAAAAACCAACACTACAATGGGCTAATACTGAAAAAGATGTCTTGAAGAAGAGTGCTA CAGCTAGTTATACATTGACTAAACCAGCTGGTGTAGAAATTAAATCAATTAAATTAGCGCTAAAAGATAA AGATGGACAACTTGTTAAAGAAGTAACGGTAGCTGAAAATAATTTAAATGCTACTTTAGATAAATTGAAA TATTATCAAGGTTACACCCTATCTACTACAATGGTTTATGATCGTGGAGAAGGTGAAGAAACTGAGAAAT TAGAAGATAAACAAATTCAATTAGACCTTAAAAAAGTTGAAATCAAAAACATTAAAGAAACAAGCTTAAT GAATGTTGATGCTGAGGGTAACGAAACTGATAAGAGCTTATTATCTGAAAAACCGACAGATGTTTCCCAA TTGTATTTACGTGTGACAACTCATGACAACAAAGTGACAAGACTTGCGGTAAGTTCAGTTGAAGAAGTTG TTGTTGATGGAAAAACATTGTACAAAGTTGTAGCCAAAGCTCCAGACTTAGTTCAACGTAGAGCTGATGA TACACTGAGTGAAGAATATGTTCATTATTTTGAAAAACAATTACCAAAAGTAAATAATGTATACTACAAC TTCAATGAACTTGTAAAAGATATGCAAGCTAATCCAATGGGTGAGTTTAAACTTGGTGCAGATTTGAATG CAGTTAACGTTAAGCCAGCAGGTAAAGCTTATGTTATGGCTAAATTTAGAGGTACTTTATCAAGTGTAGA GAATCATCAGTACACGATTCATAACTTAGAAAGACCTTTGTTTAATGAGGCTGAAGGTGCTACACTCAAA AACTTTAACTTAGGTAATGTAAATATAAACATGCCTTGGGCTGATAAAGTTGCACCTATTGGTAATATGT TTAAGAAGTCTACACTTGAGAATATCAAAGTAGTGGGTTCAGTAACAGGAAATAACGATGTAACCGGTGC TGTTAATAAGTTAGACGAAGCTAATATGCGCAATGTAGCTTTTATTGGCAAGATTAACAGTCTTGGAGAT AAAGGCTGGTGGTCTGGTGGACTTGTCAGCGAAAGTTGGCGAAGTAACACGGATAGTGTTTATTTTGACG GTGATATTGTAGGTAACAATTCTAAGTTTGGTGGTTTAGTAGCTAAAGTCAATCACGGAAGTAATCAGTG GGATGTTAAACAAAAAGGTCGTTTGACAAATTCTGTTGTTAAAGGTACTATGACTCTGAAAAATCATGGT CAAAGTGGTGGTTTAGTTCACGAAAACTATGACTGGGGTTGGGTTGAGAATAATATTAGTATGATGAAAG TCAATAACGGTGAAATTATGTATGGTTCAGGTTCTATTGACGGTGACCCATACTTTGGTTTTGACTACTT CAAAAATAATTATTATGTAAAAGATGTTGCTACTGGAGAAAGTACCTACAAGCGTTCGAAACAGATTCAG TCTATCTCTCAAGCCGAAGCAGACGCCAAAATCGCTAATATGGGGATTACTGCGAATACCTTCGCTATTC AAGATCCAGTTGTAAACAAGTTAAATCGTATCATTGATAGAGATTCTGAATATAAAGCGATTCAGGACTA CCAAGAAACAAGAAACCTAGCTTATCGAAACTTGGAAAAACTTCAACCGTTCTATAATAAAGAGTGGATT GTAAACCAAGGGAATAAGTTAACAGATGAGTCCAATCTTGTTAAGAAAACCGTTCTGTCTGTAACGGGTA TGAAATCAGGGCAATTTGTTACTGATTTATCAAGTGTGGATAAAATCATGATTCACTATGCCGATGGAAC CAAAGAAGAATTTGGGGTATCTGCGATTTCGGACTCTAGGGTAAAACAAGTCAAAGAATATAATGTAGAT GATTTAGGTGTAGTTTACACTCCTAATATGGTTGATAAGAACAGAGATTCTTTGATTACGAAAGTTAAAG AGAAGTTGAGTTCTGTTGCTTTAGACTCTGCTGAGGTTAAATCTATTACAAATAACCCTGCATCTCTATA CCTAGAAGAAAGTTTCGCTGAGGTTAGAGAGACGTTAGATAAGTTAGTGAAGTCCTTGTTAGAAAATGAA GATCATCAACTGAACAGTGATGAAGTGGCTGAGAAGGCGCTTCTCAAGAAAGTTGAAGATAATAAAGCTA AGATTATATTAGCCTTGACTTATCTAAATCGTTATTATGGTATCGACTATGATGGCTTGAACTTTAAGCA TTTGATGATGTTTAAACCAGACTTTTATGGTAAAACACCAAGTATTTTAGATTTCTTGATTCGTATAGGT TCAGCAGAAAAGAATTTAAAAGGAGATAGAAGTTTAGAAGCTTATCGTGAAGTTATTGGTGGTACTATTG GAAAAGGGGAATTAAATGGCTTGTTAGGTTATAACATGCGTTTATTCACTAAGTACACTGACTTAAATGA TTGGTTTATTCATGCTGCAAAGAACGTTTATGTTTCTGAGCCTGAGACGACTACAGAGGATTTCAAAGAC AAGCGCCATCGTATCTATGACGGTTTGAATAATGATGTTCACGGTCGTATGATTTTACCGTTATTGAATT TGAAAAAAGCGCATATTTTTGTGATTTCGACTTACAATACAATAGCCTTTAGTTCCTTTGAAAAATATGG TAAGAATACAGAAGAAGAGCGGAACGCTTATAAAGCTGAGATTGATAGGGTTGCAAAAGCACAACAACGT TACTTAGACTTCTGGTCTCGTTTAGCTTTACCGAAAGTTCGCAATCAACTTTTGAAGAGTCAAAACTCTG TACCAACTCCTGTTTGGGATAATCAAGTTTATGTAGGTTTAGGTGGTGCAAACCGTATGGGTTACGGTGA TGGGGGTCGAGTAGTAACTCCAGTTCGTGAATTATTCGGCCCGACTGATCGTTGGCACCAAATAAACTGG AATATGGGAGCGATGGCGAAGATTTATGAACGTCCTTGGAAAGATGATCAAGTTTATTTCATGGTTACAA ATATGATGGAGCCGTTCGGTATCTCAGCCTTTACCCATGAAACTACTCACGTCAATGATAGAATGGCTTA CTACGGTGGAGATTGGCACCGTGAAGGTACGGATTTAGAAGCCTTTGCTCAAGGCATGTTGCAAACACCT GATAAGTCAACAACCAATGGTGAATACGGTGCTCTCGGTATCAATATGGCTTATGAGCGTAAAAATGATG GTGAACAGCTTTACAATTATGACCCTGAGAAGTTAGATAGTAGAGAGAAAATTGATAGTTACATGAAGAA CTACAATGAGTCTATGATGATGCTTGACTACTTAGAAGCTAGTGCAGTTATTCGTCAAAATTTGTCTGAT AATTCTAAGTGGTTCAAGAAGATGGATAAAGAGTGGCGCACTAATGCAGATAGAAACCGTTTAATTGGAG AACCGCATCAGTGGGATAAATTACGTGATTTAACAGAAGAAGAGAAGAAGTTACCTATTGACAGTATTGA CAAGTTGGTAGAGAATAACTTTGTAACTCTTCATGGTATGCCGAAGAACGGTCGTTACCGCACAGAAGGT TTTGATAGCTCTTATCAACCTGTAAACATGATGGCAGGTGTCTTTGGAGGGAATACAAGTAAAAGCACCG TAGGGTCTATTTCATTTAAACATAATGCTTTCCGTATGTGGGGATACTATGGATATGAAAATGGCTTTAT TCCTTATGTTTCTAACAAGTTAAAAGGTGCTGCAAATAAAGAGAATAAAGGGCTTTTAGGTGATGATTTC ATTATCAAGAAAGTTTCTAAGAATCAATTCCAAAATCTCGAAGAGTGGAAGAAGCATTGGTATCATGAAG TTTATGATAAAGCACAAAAAGGCTTTGTTGAGATTGAGGTAGACGGAGTGAAAATTTCAACGTATGCTCA GTTACAATCCTTATTTGAAGAAGCTGTTAGCAAAGATCTTGCAGGTATGGATGATAAGAACATTAAGAAT CATTACCAATATACAGAGAATCTCAAGTGGAAAATATACAAACAACTCCTTAAAAACACAGACGGTTTCT CTAGTGATCTATTTACTGCACCACAAGCATA
Protein Sequence	>gi\|15902625\|ref\|NP_358175.1\| zinc metalloprotease [Streptococcus pneumoniae R6] MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEIISQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKKIASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLDTVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEESKVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEVVPDDTKYVDEEVVERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKGTKPVETREEVIPFATKEQEDDTLKRGTRQVAQEGVNGKKQITETYKTIRGEKTNEAPTVEETVLQAPQDEIIKKGTKGLEKPTLQWANTEKDVLKKSATASYTLTKPAGVEIKSIKLALKDKDGQLVKEVTVAENNLNATLDKLKYYQGYTLSTTMVYDRGEGEETEKLEDKQIQLDLKKVEIKNIKETSLMNVDAEGNETDKSLLSEKPTDVSQLYLRVTTHDNKVTRLAVSSVEEVVVDGKTLYKVVAKAPDLVQRRADDTLSEEYVHYFEKQLPKVNNVYYNFNELVKDMQANPMGEFKLGADLNAVNVKPAGKAYVMAKFRGTLSSVENHQYTIHNLERPLFNEAEGATLKNFNLGNVNINMPWADKVAPIGNMFKKSTLENIKVVGSVTGNNDVTGAVNKLDEANMRNVAFIGKINSLGDKGWWSGGLVSESWRSNTDSVYFDGDIVGNNSKFGGLVAKVNHGSNQWDVKQKGRLTNSVVKGTMTLKNHGQSGGLVHENYDWGWVENNISMMKVNNGEIMYGSGSIDGDPYFGFDYFKNNYYVKDVATGESTYKRSKQIQSISQAEADAKIANMGITANTFAIQDPVVNKLNRIIDRDSEYKAIQDYQETRNLAYRNLEKLQPFYNKEWIVNQGNKLTDESNLVKKTVLSVTGMKSGQFVTDLSSVDKIMIHYADGTKEEFGVSAISDSRVKQVKEYNVDDLGVVYTPNMVDKNRDSLITKVKEKLSSVALDSAEVKSITNNPASLYLEESFAEVRETLDKLVKSLLENEDHQLNSDEVAEKALLKKVEDNKAKIILALTYLNRYYGIDYDGLNFKHLMMFKPDFYGKTPSILDFLIRIGSAEKNLKGDRSLEAYREVIGGTIGKGELNGLLGYNMRLFTKYTDLNDWFIHAAKNVYVSEPETTTEDFKDKRHRIYDGLNNDVHGRMILPLLNLKKAHIFVISTYNTIAFSSFEKYGKNTEEERNAYKAEIDRVAKAQQRYLDFWSRLALPKVRNQLLKSQNSVPTPVWDNQVYVGLGGANRMGYGDGGRVVTPVRELFGPTDRWHQINWNMGAMAKIYERPWKDDQVYFMVTNMMEPFGISAFTHETTHVNDRMAYYGGDWHREGTDLEAFAQGMLQTPDKSTTNGEYGALGINMAYERKNDGEQLYNYDPEKLDSREKIDSYMKNYNESMMMLDYLEASAVIRQNLSDNSKWFKKMDKEWRTNADRNRLIGEPHQWDKLRDLTEEEKKLPIDSIDKLVENNFVTLHGMPKNGRYRTEGFDSSYQPVNMMAGVFGGNTSKSTVGSISFKHNAFRMWGYYGYENGFIPYVSNKLKGAANKENKGLLGDDFIIKKVSKNQFQNLEEWKKHWYHEVYDKAQKGFVEIEVDGVKISTYAQLQSLFEEAVSKDLAGMDDKNIKNHYQYTENLKWKIYKQLLKNTDGFSSDLFTAPQA
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: zmpB mutant is attenuated in mice (Chiavolini et al., 2003).
COG	COG3583S, under S: Function unknown
References	*Chiavolini et al., 2003:* Chiavolini D, Memmi G, Maggi T, Iannelli F, Pozzi G, Oggioni MR. The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice. BMC microbiology. 2003; 3; 14. [PubMed: 12841855].


Search: for Help

zmpB from Streptococcus pneumoniae R6