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lytC from Streptococcus pneumoniae R6

Victor ID 3101
Gene Name lytC from Streptococcus pneumoniae R6
Sequence Strain (Species/Organism) Streptococcus pneumoniae R6
NCBI Gene ID 933163
NCBI Protein GI 15903474
Locus Tag spr1431
Protein Accession NP_359024.1
Other Database IDs UniProtKB-ID: Q8DP07_STRR6
UniRef100: UniRef100_Q8DP07
UniRef90: UniRef90_B2IR92
UniRef50: UniRef50_D3HAA5
UniParc: UPI00000E3658
EMBL: AE007317
EMBL-CDS: AAL00235.1
RefSeq_NT: NC_003098.1
PDB: 2WW5
PDB: 2WWC
PDB: 2WWD
EnsemblGenome: EBSTRG00000015641.
EnsemblGenome_TRS: EBSTRT00000015641
EnsemblGenome_PRO: EBSTRP00000015037
GenomeReviews: AE007317_GR
KEGG: spr:spr1431
eggNOG: COG5263
HOGENOM: HBG697709
OMA: KKWGYMA
ProtClustDB: CLSK560466
BioCyc: SPNE171101:SPR1431-MONOMER
Taxonomy ID 171101
Gene Starting Position 1414510
Gene Ending Position 1416015
Gene Strand (Orientation) -
Protein Name 1,4-beta-N-acetylmuramidase
DNA Sequence 
>gi|15902044:1414510-1416015 Streptococcus pneumoniae R6, complete genome
CTTAATACCAAACGCTGACATCTACGCGCCCTTGGATTCCTTTCATGTATTCAGAAGAGGTATATTGCCA
ACCTTTTTCTCCTGAATAATAAGGGTTTTCCCATTCTAAAGCATTCGTATAGGCCGCTACCCAGTTTACA
TGTTTTAAAATATCTGGGTGTTTTAAACGCGTCTGTAATAAACTACGATAGCTATAGACATATACATTTT
GATAACCCGCCTGCTTCATCGTGTCCATGTACTTGTTGATGATTTTAACCCAAGTGTCTGTATCACTTGG
AGCTCTCTTGCTCTTATTTACATATTCCCAGTTCTCAACATCATAATAGATAGGGTAAGACAGGTTCATA
TTGTATTTCTTTATAAGTTCAATGGTCTGTTTAGCGTCATTCTCAGCATCGGTCTCATTTTCAGCATAGG
TATAGAGATAGACACCATAAGGAATTCCCAGACGGTTTAACTCCTTAATGTTATGCGCCAATTCCTTGTC
TTCTTTACCGCTATAACCTAGACGAACAATGACACCATCCACCTTGTTCTCATCAATAACCTTTTTCCAA
TCATTGATACGACCATTGTGCTCACTAATATCAATGATTTTCTTAGCATGTTCGGTTCCCACTTGTTCTT
CTCTATTATTAAAGAAATAGCGTTTACCATCTCTGTGAACCCAGCCGACATTCAAATCTTTCTTTTCTTT
GAGCTCACCAGAGGCCGCAAAGATATAGCGAGCACCATCCATAATCACTTCGTCAGTCGCCATGGCACCA
CTTCCAGTCAAATAGTAGTTGCCTTGCCACTCATTCCGAGCCATATAGCCCCACTTCTTGAAATAGTACC
ATTTGCCGCCCACTTTTTGCCACTCTTGGTTAGCATAAGTTCCATCGGATTTTAGATAAAAATAAGCAGA
ATAAGCTGGATCATAGAGCCATTCATTTTGTATCATAGCTCCTTGACCATTCAAGAAATAACTTCCTTGC
CATTGGCTTTTAGCCATGTAACCCCACTTCTTGAAGTAGTACCACTTATTTCCAATCAATTGCCATTCTT
GATGAGCATAAGCCCCATCTGACTTGAGATAAAACCAACTCTTGTAATTACTGTCATAGATCCACTCGTT
TTGGGCCATATATCCACCTGATTTCAGGTAGTAATTTCCATGCCATTCATTCTGCGAGTAACGACCATCT
GAATTAATATAAAACCAAGCCTTATAGTAGTTGTCAAAAATCCATTCACTTTGAGCTTTAGAACCATCAT
CCTTTACATAATAATCCCCATCCCAGTAGGCAGCAGCATTAGTCTGTACTTCTGCGCTCGTTTGCGTTTT
ATTAGAAGACTGATTTTGCTCTGAACTACTTGAAGCTGTCGTTGTATCCTGCGAAGTTTTTGCTACTTCA
GTTTCATTTGCAGCGACATGACTAGTTGCCAAGCCTAGTAAACAGATACTTGCTAATCCAATTTTTATTT
TCAATCTTTCCTCTCCTATAAAAAATGTAACAGACA
Protein Sequence 
>gi|15903474|ref|NP_359024.1| 1,4-beta-N-acetylmuramidase [Streptococcus pneumoniae R6] MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQDTTTASSSSEQNQSSNKTQTSAEVQTNAAAYWDGDYYVKDDGSKAQSEWIFDNYYKAWFYINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGNKWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQKVGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLNVGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENKVDGVIVRLGYSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYPIYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKHPDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lytC mutant have reduced colonization of rat nasopharynx compared to wild type (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].