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srtA from Streptococcus pneumoniae D39

Victor ID 3095
Gene Name srtA from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4442999
NCBI Protein GI 116515518
Locus Tag SPD_1076
Protein Accession YP_816547.1
Other Database IDs UniProtKB-ID: Q04KA1_STRP2
UniRef100: UniRef100_E0T061
UniRef90: UniRef90_E0T061
UniRef50: UniRef50_A3CN68
UniParc: UPI00000E35C5
EMBL: CP000410
EMBL-CDS: ABJ53814.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000020492.
EnsemblGenome_TRS: EBSTRT00000020492
EnsemblGenome_PRO: EBSTRP00000019732
GenomeReviews: CP000410_GR
KEGG: spd:SPD_1076
eggNOG: COG3764
HOGENOM: HBG517863
OMA: AGTMKED
ProtClustDB: CLSK876837
Taxonomy ID 373153
Gene Starting Position 1102250
Gene Ending Position 1102993
Gene Strand (Orientation) -
Protein Name sortase
DNA Sequence 
>gi|116515308:1102250-1102993 Streptococcus pneumoniae D39, complete genome
ATTAATAAAATTGTTTATATGGTTGATTGAAAGCTGTTAGGATTTCATCAGATGTTTGTGAATAATCTTT
TGTTTCTTTCAAATCACCTTTGACAATAATACGTTCTGTAGCAGCAAGGTCTTCACAGGTTACTAATGTG
ATTTCATTGACCCCATCTCTATCATCAACTTCATCAACACGATCTGGTGTCACACGTTTGACTTCACGTA
TTTCATAAGTATAAACTTTATTTTTATCGGTTAGATAAATCTTCATGCCATTTTTAGCATTATCTAAAGG
AGAAAATAACATTTTATTAGCATTATCAACACCAAAGATATGGTGACTAGCTAGACTATAATTTCCTTCT
CCCATTACTTGCTCGCGTTTCATTGTACCAGCTCCGTAGAAGAGATTAACATTATCAAGTCCTTTAAAAA
TCGGCAAATTCATTTCCAATTCAGGAATTGCAATTCCCCCAATAACTGGTAATTTTTGAGCATCCCATTG
AGAAGTTAGAACAGCTTCCGAAGAGATAGCTTTGACAGAATCAAAGTCAAAATTGCCTTCTGTATCCTGA
TTTTCTTCTAATTTTTCTTTTGATACCTGGCTAACTTGATACTTATTGGTATTCCAGACTATGAAAATAT
TTCGAATTTGAGTATTAAAAATCAAAGCCAGTGACAGTAATATCAGAAATCCTGCTAGGATATTTGTCAG
CAGATTTTTTCGCTTGTTTTTCTTTTTATTATTTTTTTGAGACA
Protein Sequence 
>gi|116515518|ref|YP_816547.1| sortase [Streptococcus pneumoniae D39] MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVWNTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPELEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNAKNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIVKGDLKETKDYSQTSDEILTAFNQPYKQFY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The srtA mutant colonized the nasopharynx of chinchillas at a significantly lower level than the wild type (Chen et al., 2005).
COG COG3764M, under M: Cell wall/membrane/envelope biogenesis
References
Chen et al., 2005: Chen S, Paterson GK, Tong HH, Mitchell TJ, DeMaria TF. Sortase A contributes to pneumococcal nasopharyngeal colonization in the chinchilla model. FEMS microbiology letters. 2005; 253(1); 151-154. [PubMed: 16246506].