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potD from Streptococcus pneumoniae D39

Victor ID 3088
Gene Name potD from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4442604
NCBI Protein GI 116516276
Locus Tag SPD_1218
Protein Accession YP_816685.1
Other Database IDs UniProtKB-ID: Q04JW3_STRP2
UniRef100: UniRef100_Q04JW3
UniRef90: UniRef90_C1CEX4
UniRef50: UniRef50_Q2YX72
UniParc: UPI00000E3610
EMBL: CP000410
EMBL-CDS: ABJ54572.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000019367.
EnsemblGenome_TRS: EBSTRT00000019367
EnsemblGenome_PRO: EBSTRP00000018607
GenomeReviews: CP000410_GR
KEGG: spd:SPD_1218
eggNOG: COG0687
HOGENOM: HBG638705
OMA: WADYVAP
ProtClustDB: CLSK884080
Taxonomy ID 373153
Gene Starting Position 1250317
Gene Ending Position 1251387
Gene Strand (Orientation) -
Protein Name spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein
DNA Sequence 
>gi|116515308:1250317-1251387 Streptococcus pneumoniae D39, complete genome
CCTACTTCCGATACATTTTAAACTGTAGGAAGAGGTCGCTATATTTCCCTGTCCATTTATGGTCAAATTT
CTCATAAACTTCTAGGTGTTTCATGGTTTCAACATCGGGATAGAAGGCCTTATCTTCCTTTGTTTCCTCT
GGGAGCAATTCCTTCGCTGGTAGGTTTGGTGTTGAATAGCCGACATACTCCGCATTTTGGAGAGCATTTT
CAGGTTTCAACATAAAGTTGATAAAGGCATAGGCTGAGTCTTGATTTTTAACTGTTTTGGGAATGACCAT
ATTGTCAAACCAAAGATTGCTGGCCTCTGTCGGTACCACATAACGTAGATTTTCATTTTTTTCTAACATT
TGGCTGGCTTCACCAGAGAAGGTCACGCCGATTGCAACATTATTCTGAATCATGTAGCCCTTCATCTCGT
CCGCAACGATAGCCTTGATATTTGGAGTCAGTTTGTAGAGCTTATCCACTGTCTCTTCCAACTGCTGCGG
ATCCTTGGAGTTGAGGCTGTAGCCGAGGGAATTGAGTCCTAGTCCCAGCACCTCACGCGCCCCATCAAAA
AGCATGATAGAATTCTTATACTCCAGCTTCCAAAGGTCATCCCAATGCTCAGGCGCTTCATCTACCATGG
TTTCGTTGTAGACAATTCCTAAGGTTCCCCAGAAGTAAGGGATGGAGAATTTATTACCTGGGTCAAAGGA
CTGGTTGAGAAACTCTGGTCCGATATTTTCGATTCCTTCAATTTTTGAATAATCAAGCGGAACCAAGAGG
TCTTCGTCCTTCATCTTGTTAATCATGTATTCACTTGGAATGGCAATATCGTAGGTCGTTCCACCCTGCT
TTATCTTAGTGTACATGGCTTCGTTGGAGTCAAAAGCCTCGTACTGAACTTGAATTCCTGTTTCTTCTGT
AAACTGAGTCAAGAGTTCAGGATCGATATAGTCTCCCCAGTTATAGATAACCAATTTTTGACTATCTCGA
CTATTGATTTTACTATCTAAATGAGTCGCAATTCCCCACAAGACAAGGATAATCGCTGCAATTCCTGCTA
AAAATGAATAGATTTTTTTCA
Protein Sequence 
>gi|116516276|ref|YP_816685.1| spermidine/putrescine ABC transporter spermidine/putrescine-binding protein [Streptococcus pneumoniae D39] MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGDYIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDLLVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDLWKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVADEMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDSAYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYEKFDHKWTGKYSDLFLQFKMYRK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: potD mutant is attenuated in pulmonary and systemic models of infection in mice (Ware et al., 2006).
COG COG0687E, under E: Amino acid transport and metabolism
References
Ware et al., 2006: Ware D, Jiang Y, Lin W, Swiatlo E. Involvement of potD in Streptococcus pneumoniae polyamine transport and pathogenesis. Infection and immunity. 2006; 74(1); 352-361. [PubMed: 16368990].