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aga

Victor ID 3087
Gene Name aga
Sequence Strain (Species/Organism) Streptococcus pneumoniae
NCBI Gene ID 4442466
NCBI Protein GI 116515396
Locus Tag SPD_1678
Protein Accession YP_817127.1
Other Database IDs UniProtKB-ID: Q04IR1_STRP2
UniRef100: UniRef100_B5E212
UniRef90: UniRef90_E0SXF9
UniRef50: UniRef50_E0SXF9
UniParc: UPI00000E494D
EMBL: CP000410
EMBL-CDS: ABJ53692.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000019628.
EnsemblGenome_TRS: EBSTRT00000019628
EnsemblGenome_PRO: EBSTRP00000018868
GenomeReviews: CP000410_GR
KEGG: spd:SPD_1678
eggNOG: COG3345
HOGENOM: HBG302872
OMA: RNDLGMM
ProtClustDB: CLSK626013
Taxonomy ID 373153
Gene Starting Position 1693399
Gene Ending Position 1695561
Gene Strand (Orientation) -
Protein Name alpha-galactosidase AgaN
DNA Sequence 
>gi|116515308:1693399-1695561 Streptococcus pneumoniae D39, complete genome
ATCATAGTTTTCTAAAAATATACTGTCTACTCAAAAAATCTCCTTGGGATAAGATAACAGTTAAGCCCGC
ATACATTAGTTCTGCACCTGAGTAAACTTCGCCATTTTCCTGTAATTTATATAGTCCCTCTTCATCCAAA
TCTTTTAATTTTAAAGTTGTTTCCATGGTCTCTACAACAGATAAAACGCGAACGTAGGTTACAATCGTTT
GATTTCCGTAATTAAATTGTACAGCTGCTTCATTGGATGCAGTATCAGGATTAATTAGTCTATACTGCTG
TCCTAACTGAACTACTGGTCGTAATTCTTTATACAAGTTCACCTGATTAGCAATCGTAGCTTTCTCTTCA
TCTGATAAATTTGTCAAATCAAGCTCATAGCCCAAATTTCCCATCATTGCTACATGGCCACGTGTTTCTA
ATGGTGTCATTCGTCCCATCTGATGATTCGGTACTGCTGACACATGAGCCCCCATAGAAATGGTTGGATA
GAGATAGGATGAACCGTATTGAATTGGTAAACGTGCAATGGCATCAGTATTATCACTAGCCCAGACTTGT
GGGAAATAGCGTATCATACCAAGATCATTTCGTCCACCACCACCAGAGCAGGACTCAAAGAGAATATGGC
TGTGCTTCTCTGTCAGATAAGAAACGAGTTCGTAAAGTCCCAGCATGTACTGATGAGATTGCATCTGTGT
CTCTAGATAAGTTAATCCATTCCCTAGCTTAGTGATATTGCGGTTCATATCCCATTTAATGTAATCAATC
TCATGATAAGATAGGAGTTGATCTAAGACACTTTTCAAGTATTCTACTACCTGAGGATTGGCAAGATTAA
GTACTAATTGATTCCGAGAATAAGTATGCTCATAATCAGGAACCTGAATAGCCCAGTCAGGATGTTGACG
ATACAAATCACTATCTACAGAAATCATTTCGGGTTCTAACCAAAGTCCAAACTGCAAACCTCTTTCATGG
ATAGCTGAAATCAGACTTTCTAGACTTCCACCCAGTTTTTCCTCATTAACAACCCAATCACCTAAAGCAC
GATTATCATCAAAACGATTGCCAAACCAACCATCATCTAATACAAAAAGTTCAATGCCAACTTTCTTAGC
TTCATCTGCTAACTCTAACAGTTTTTCTCTCTGAAAGTCAAAGTAAGTAGCTTCCCAGTTATTGATTAGA
ATTGGACGTTCTTTTTTAGAAAATTCACTTAGAATAATGTGCTTCAGTACAAAATTCTGACTTTCATGAC
TAATACCAGTTAATCCCTGATCTGAATGAGTCACTAAAGCTACCGGTGTTTCAAAGTATTCCTCAGGGGC
TAACTTCCAAGAAAAGTTTTCTGGATTAATGCCAATAGCCACCCGAACTTCATTCAATTGATTTTTTTGA
ACAAAAGCTTCAAAGTTGCCACTATACATTAGTTGAATAGCAAACACATTCCCAGCATCCTCTGTGACTC
CTTGTTCGCATAGTAGAAGAGCTGGTGTTTGAGCATGACCAGAAGCACCTCGGTTTGAACTAATCGAAAA
GATTCCTTGTTCTACCTGTTGACGTCTAACAGTCTTTTCACGAGCATAAGCACCCTGCAGAGTTACTATT
TCGTAATCTGCAGCTGGAAAATCAGCCATAAAAGAAAAATCTTTATGGATGACAACTTCCTGATTACTAT
TATTATCTAATTTACTGTAGCTAGCAATAGTCGCATCATTATTAAAAGTAGTATAATACAAAGTCAGACT
AAGTTGAGCCTTAGAATCTTCTAACATTAAGACAAGAGTCTCTGTATCGTCCATGCTATGTGGAGAAGGT
AAGCCCTGTGGACCATTCTGACCTTTTAAAATCTTTGCTTCTACAAATCGAAAGTCTGTTACTTCAGTTA
CACTATGCTGAACCTGTATAGTTGGTTTCCTAAAATCTCCTAAGCCATGTTGTCCAAAAATCTGTCGCTG
AGTATCTAAACTAAAGGTTCGATTAGTAGCCGTTGGATTTCCTGAAAAGGCATGGTCTCGTTCATAAACA
CTATTGGAACCTTTATAGTTCTTAATAGTCTTTCCTAAATGTTTCAAAAGTAAGTAGCCATTTCGATTTT
CAATAATCAAACTTAGATTTTTACTCTCAACATAAAATAGATTATTCTCTATCCTAACTCCCA
Protein Sequence 
>gi|116515396|ref|YP_817127.1| alpha-galactosidase AgaN [Streptococcus pneumoniae D39] MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSNSVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVEAKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLDNNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGASGHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSWKLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATYFDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLISAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVVEYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLTEKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGAHVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPVVQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLYKLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: an aga mutant was attenuated in a murine model (Lau et al., 2001)
COG COG3345G, under G: Carbohydrate transport and metabolism
References
Lau et al., 2001: Lau GW, Haataja S, Lonetto M, Kensit SE, Marra A, Bryant AP, McDevitt D, Morrison DA, Holden DW. A functional genomic analysis of type 3 Streptococcus pneumoniae virulence. Molecular microbiology. 2001; 40(3); 555-571. [PubMed: 11359563].